Azione protettiva - Coniugati ligasi-ligando-linker E3 Supplier | High Purity

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(S,R,S)-AHPC-phenol-alkylC6-amine 2HCl
CAS: 2376990-28-0 Formula: C₃₀H₄₇Cl₂N₅O₅S Peso molecolare: 660.7

Solido ≥95%

◐ .Su ordinazione · 8–12 settimane Oggetto #: V287681
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(2S,4R)-1-[(2S)-2-acetamido-3,3-dimethylbutanoyl]-N-[[2-(6-aminohexoxy)-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-hydroxypyrrolidine-2-carboxamideshow more

SMILES

CC1=C(SC=N1)C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@@H](NC(C)=O)C(C)(C)C)=O)=O)C(OCCCCCCN)=C2.Cl.Cl

InChIKey
ZDPHPLMGGQWIRY-SGROTYDGSA-N

InChI

1S/C30H45N5O5S.2ClH/c1-19-26(41-18-33-19)21-10-11-22(25(14-21)40-13-9-7-6-8-12-31)16-32-28(38)24-15-23(37)17-35(24)29(39)27(30(3,4)5)34-20(2)36;;/h10-show more
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(S,R,S)-AHPC-PEG₂-NH₂ hydrochloride
CAS: 2097973-72-1 PubChem CID: 131704496 Formula: C₂₈H₄₂ClN₅O₆S Peso molecolare: 612.2

Solido ≥95%

◐ .Su ordinazione · 8–12 settimane Oggetto #: S463420
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(2S,4R)-1-[(2S)-2-[[2-[2-(2-aminoethoxy)ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidinshow more

SMILES

CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)COCCOCCN)O.Cl

InChIKey
SYAOHFUUVWFWJH-ZBXLSASTSA-N

InChI

1S/C28H41N5O6S.ClH/c1-18-24(40-17-31-18)20-7-5-19(6-8-20)14-30-26(36)22-13-21(34)15-33(22)27(37)25(28(2,3)4)32-23(35)16-39-12-11-38-10-9-29;/h5-8,17,2show more

Sinonimi
VH032-PEG2-NH2 hydrochloride | VHL Ligand-Linker Conjugates 3 hydrochloride | E3 ligase Ligand-Linker Conjugates 6 | ...
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2-(2,6-Dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)isoindoline-1,3-dione
CAS: 2222114-22-7 PubChem CID: 134413827 Formula: C₁₇H₁₇FN₄O₄ Peso molecolare: 360.34

◐ .Su ordinazione · 8–12 settimane Oggetto #: D1025390
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2-(2,6-dioxopiperidin-3-yl)-5-fluoro-6-piperazin-1-ylisoindole-1,3-dione

SMILES

C1CC(=O)NC(=O)C1N2C(=O)C3=CC(=C(C=C3C2=O)F)N4CCNCC4

InChIKey
YNGDWIBEYDEYGU-UHFFFAOYSA-N

InChI

1S/C17H17FN4O4/c18-11-7-9-10(8-13(11)21-5-3-19-4-6-21)17(26)22(16(9)25)12-1-2-14(23)20-15(12)24/h7-8,12,19H,1-6H2,(H,20,23,24)
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5-(Aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
CAS: 1010100-22-7 PubChem CID: 67019706 Formula: C₁₄H₁₄ClN₃O₄ Peso molecolare: 323.73

≥98%

◐ .Su ordinazione · 8–12 settimane Oggetto #: A980458
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5-(aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride

SMILES

C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C=C(C=C3)CN.Cl

InChIKey
ODZXEQVQLJKSQH-UHFFFAOYSA-N

InChI

1S/C14H13N3O4.ClH/c15-6-7-1-2-8-9(5-7)14(21)17(13(8)20)10-3-4-11(18)16-12(10)19;/h1-2,5,10H,3-4,6,15H2,(H,16,18,19);1H
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E3 ligase Ligand-Linker Conjugates 14
CAS: 1957236-21-3 PubChem CID: 121439766 Formula: C₂₅H₃₁F₃N₄O₁₁ Peso molecolare: 620.53

≥99%

◐ .Su ordinazione · 8–12 settimane Oggetto #: E1021754
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N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid

SMILES

C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)NCCOCCOCCOCCN.C(=O)(C(F)(F)F)O

InChIKey
BLYRZYHKZRITLJ-UHFFFAOYSA-N

InChI

1S/C23H30N4O9.C2HF3O2/c24-6-8-33-10-12-35-13-11-34-9-7-25-19(29)14-36-17-3-1-2-15-20(17)23(32)27(22(15)31)16-4-5-18(28)26-21(16)30;3-2(4,5)1(6)7/h1-3,show more
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E3 ligase Ligand-Linker Conjugates 17
CAS: 1950635-16-1 PubChem CID: 121411067 Formula: C₂₅H₃₁F₃N₄O₈ Peso molecolare: 572.5

≥99%

◐ .Su ordinazione · 8–12 settimane Oggetto #: E1305210
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N-(8-aminooctyl)-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid

SMILES

C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)NCCCCCCCCN.C(=O)(C(F)(F)F)O

InChIKey
AJVLNIUPDHKOPS-UHFFFAOYSA-N

InChI

1S/C23H30N4O6.C2HF3O2/c24-12-5-3-1-2-4-6-13-25-19(29)14-33-17-9-7-8-15-20(17)23(32)27(22(15)31)16-10-11-18(28)26-21(16)30;3-2(4,5)1(6)7/h7-9,16H,1-6,1show more
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E3 ligase Ligand-Linker Conjugates 16
CAS: 1799711-25-3 PubChem CID: 121410950 Formula: C₂₁H₂₃F₃N₄O₈ Peso molecolare: 516.42

≥99%

◐ .Su ordinazione · 8–12 settimane Oggetto #: E1317449
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N-(4-aminobutyl)-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid

SMILES

C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)NCCCCN.C(=O)(C(F)(F)F)O

InChIKey
XVUPBWSTMLHSHM-UHFFFAOYSA-N

InChI

1S/C19H22N4O6.C2HF3O2/c20-8-1-2-9-21-15(25)10-29-13-5-3-4-11-16(13)19(28)23(18(11)27)12-6-7-14(24)22-17(12)26;3-2(4,5)1(6)7/h3-5,12H,1-2,6-10,20H2,(H,show more
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E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate
CAS: 1950635-14-9 PubChem CID: 121411039 Formula: C₂₃H₂₇F₃N₄O₈ Peso molecolare: 544.48

≥99%

◐ .Su ordinazione · 8–12 settimane Oggetto #: E987676
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N-(6-aminohexyl)-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid

SMILES

C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)NCCCCCCN.C(=O)(C(F)(F)F)O

InChIKey
KNNGJZWEJKPKSW-UHFFFAOYSA-N

InChI

1S/C21H26N4O6.C2HF3O2/c22-10-3-1-2-4-11-23-17(27)12-31-15-7-5-6-13-18(15)21(30)25(20(13)29)14-8-9-16(26)24-19(14)28;3-2(4,5)1(6)7/h5-7,14H,1-4,8-12,22show more
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Thalidomide-O-amido-C3-NH2 TFA
CAS: 2022182-58-5 PubChem CID: 139291000 Formula: C₂₀H₂₁F₃N₄O₈ Peso molecolare: 502.4

≥99%

◐ .Su ordinazione · 8–12 settimane Oggetto #: T1018860
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N-(3-aminopropyl)-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid

SMILES

C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)NCCCN.C(=O)(C(F)(F)F)O

InChIKey
OKTNKIORKNBBAG-UHFFFAOYSA-N

InChI

1S/C18H20N4O6.C2HF3O2/c19-7-2-8-20-14(24)9-28-12-4-1-3-10-15(12)18(27)22(17(10)26)11-5-6-13(23)21-16(11)25;3-2(4,5)1(6)7/h1,3-4,11H,2,5-9,19H2,(H,20,2show more
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Thalidomide-O-amido-C3-PEG3-C1-NH2
CAS: 1799711-29-7 PubChem CID: 121411156 Formula: C₂₇H₃₅F₃N₄O₁₁ Peso molecolare: 534.5611402

≥99%

◐ .Su ordinazione · 8–12 settimane Oggetto #: T932703
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N-[3-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]propyl]-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid

SMILES

C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)NCCCOCCOCCOCCCN.C(=O)(C(F)(F)F)O

InChIKey
QLXAREGCLBGPLF-UHFFFAOYSA-N

InChI

1S/C25H34N4O9.C2HF3O2/c26-8-2-10-35-12-14-37-15-13-36-11-3-9-27-21(31)16-38-19-5-1-4-17-22(19)25(34)29(24(17)33)18-6-7-20(30)28-23(18)32;3-2(4,5)1(6)7show more
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Thalidomide-O-amido-PEG2-C2-NH2 (TFA)
CAS: 1957235-75-4 PubChem CID: 121439750 Formula: C₂₃H₂₇F₃N₄O₁₀ Peso molecolare: 576.48

≥99%

◐ .Su ordinazione · 8–12 settimane Oggetto #: T1305211
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N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid

SMILES

C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)NCCOCCOCCN.C(=O)(C(F)(F)F)O

InChIKey
JQWXWSIQGKGHEB-UHFFFAOYSA-N

InChI

1S/C21H26N4O8.C2HF3O2/c22-6-8-31-10-11-32-9-7-23-17(27)12-33-15-3-1-2-13-18(15)21(30)25(20(13)29)14-4-5-16(26)24-19(14)28;3-2(4,5)1(6)7/h1-3,14H,4-12,show more
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Thalidomide-PEG2-C2-NH2 TFA
CAS: 2097509-36-7 PubChem CID: 132260540 Formula: C₂₁H₂₅F₃N₄O₈ Peso molecolare: 518.44

≥99%

◐ .Su ordinazione · 8–12 settimane Oggetto #: T954974
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4-[2-[2-(2-aminoethoxy)ethoxy]ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;2,2,2-trifluoroacetic acid

SMILES

C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCN.C(=O)(C(F)(F)F)O

InChIKey
MKEOTJQAATZPDV-UHFFFAOYSA-N

InChI

1S/C19H24N4O6.C2HF3O2/c20-6-8-28-10-11-29-9-7-21-13-3-1-2-12-16(13)19(27)23(18(12)26)14-4-5-15(24)22-17(14)25;3-2(4,5)1(6)7/h1-3,14,21H,4-11,20H2,(H,2show more

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Domande frequenti

How do I choose the right E3 Ligase Ligand-Linker Conjugates for my conjugate design?

Work from both ends inward: the reactive handle that has to couple to your payload or protein, and the linker length or ternary-complex geometry the design needs, then match an E3 Ligase Ligand-Linker Conjugates entry to both. Solubility and stability under conjugation and storage conditions decide whether a design survives scale-up.

What does E3 Ligase Ligand-Linker Conjugates cover?

E3 Ligase Ligand-Linker Conjugates is a top-level listing in our catalogue. Use the filters and search on the listing page to narrow by the attributes that matter for your work, or browse the neighbouring categories from the main navigation.

What specifications matter most for E3 Ligase Ligand-Linker Conjugates?

For E3 Ligase Ligand-Linker Conjugates, check purity by HPLC, identity by MS, the reactive group and its protection state, linker length or PEG polydispersity, and solubility in your conjugation solvent. Moisture-sensitive handles need controlled storage and prompt use after opening. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

What if the E3 Ligase Ligand-Linker Conjugates I need is not listed?

Search E3 Ligase Ligand-Linker Conjugates by SMILES first, since close analogs are often listed under a neighbouring subcategory. Custom synthesis enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.