≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Product Description：
2-Chloromandelic acid (2-ClMA) is a mandelic acid derivative. A report based on its solid state-NMR, X-ray powder diffraction (XPRD) and Fourier transform infrared spectroscopy (FTIR) data reveals that in solid state 2-ClMA exists as a racemic compound. The study also suggests that the crystals of racemic 2-ClMA belongs the monoclinic space group P21/c. The efficiency of (R)-(+)-N-benzyl-1-phenylethylamine in resolving racemate 2-ClMA has been investigated.
Product Application：
2-Chloromandelic acid, is used as a pharmaceutical intermediate as well as in the medicine industry. It is used as a intermediate of clopidrogrel.
| Pubchem Sid | 488187072 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488187072 |
| Sorrisi canonici | C1=CC=C(C(=C1)C(C(=O)O)O)Cl |
| IUPAC Name | 2-(2-chlorophenyl)-2-hydroxyacetic acid |
| InChIKey | RWOLDZZTBNYTMS-UHFFFAOYSA-N |
| INCHI | 1S/C8H7ClO3/c9-6-4-2-1-3-5(6)7(10)8(11)12/h1-4,7,10H,(H,11,12) |
| Isomeri SMILES | C1=CC=C(C(=C1)C(C(=O)O)O)Cl |
| WGK Germania | 3 |
| Peso molecolare | 186.59 |
| Reaxy-Rn | 2367070 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2367070&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Classe | Benzene and substituted derivatives |
| Subclass | Halobenzenes |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Chlorobenzenes |
| Alternative Parents | Aryl chlorides Alpha hydroxy acids and derivatives Secondary alcohols Monocarboxylic acids and derivatives Carboxylic acids Organochlorides Organic oxides Hydrocarbon derivatives Carbonyl compounds Aromatic alcohols |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Chlorobenzene - Alpha-hydroxy acid - Aryl chloride - Aryl halide - Hydroxy acid - Secondary alcohol - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organooxygen compound - Organochloride - Organohalogen compound - Alcohol - Organic oxygen compound - Carbonyl group - Aromatic alcohol - Hydrocarbon derivative - Organic oxide - Aromatic homomonocyclic compound |
| Descrizione | This compound belongs to the class of organic compounds known as chlorobenzenes. These are compounds containing one or more chlorine atoms attached to a benzene moiety. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Data | Oggetto |
|---|---|---|---|
 L2207477 | Certificate of Analysis | Sep 07, 2026 | C107592 |
| L2207478 | Certificate of Analysis | Sep 07, 2026 | C107592 |
| L2207479 | Certificate of Analysis | Sep 07, 2026 | C107592 |
| L2207489 | Certificate of Analysis | Sep 07, 2026 | C107592 |
| L2207567 | Certificate of Analysis | Sep 07, 2026 | C107592 |
| L2207569 | Certificate of Analysis | Sep 07, 2026 | C107592 |
| K2117744 | Certificate of Analysis | Sep 04, 2025 | C107592 |
| K2117747 | Certificate of Analysis | Sep 04, 2025 | C107592 |
| K2117796 | Certificate of Analysis | Sep 04, 2025 | C107592 |
| K2117745 | Certificate of Analysis | Sep 04, 2025 | C107592 |
| K1926155 | Certificate of Analysis | Sep 08, 2023 | C107592 |
| C2321021 | Certificate of Analysis | Sep 16, 2021 | C107592 |
| Solubilità | Very soluble in water. |
|---|---|
| Sensibilità | light sensitive |
| Punto di fusione (°C) | 91°C |
| Peso molecolare | 186.590 g/mol |
| XLogP3 | 1.500 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 2 |
| Exact Mass | 186.008 Da |
| Monoisotopic Mass | 186.008 Da |
| Topological Polar Surface Area | 57.500 Ų |
| Heavy Atom Count | 12 |
| Formal Charge | 0 |
| Complexity | 172.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Yuanjing Lin, Jialiang Guo, Hang Lin, Jincai Wang, Govert W. Somsen, Jacques Crommen, Zhengjin Jiang. (2017) Effect of fabrication strategy on the enantioseparation performance of β-cyclodextrin-functionalized polymethacrylate monoliths: A comparative evaluation. JOURNAL OF SEPARATION SCIENCE, 40 (19): (3754-3762). [PMID:28749038] [10.1002/jssc.201700424] |
| 2. Jialiang Guo, Yuan Xiao, Yuanjing Lin, Jacques Crommen, Zhengjin Jiang. (2016) Effect of the crosslinker type on the enantioseparation performance of β-cyclodextrin functionalized monoliths prepared by the one-pot approach. JOURNAL OF CHROMATOGRAPHY A, [PMID:27268520] [10.1016/j.chroma.2016.05.078] |
| 3. Jialiang Guo, Yuan Xiao, Yuanjing Lin, Qiaoxuan Zhang, Yiqun Chang, Jacques Crommen, Zhengjin Jiang. (2016) Influence of the linking spacer length and type on the enantioseparation ability of β-cyclodextrin functionalized monoliths. TALANTA, [PMID:26992519] [10.1016/j.talanta.2016.02.016] |
