2-Thiouracil(2TU) - 10mM in DMSO , CAS No.141-90-2

CAS: 141-90-2 Cat. No.: T409049 Formula: C₄H₄N₂OS Peso molecolare: 128.15 Beilstein Registry Number: 112227 Numero EC: 205-508-8 PubChem CID: 1269845

GRADE & PURITY 10mM in DMSO

Synonyms

2-thioxo-2,3-dihydropyrimidin-4(1H)-one

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Information

2-Thiouracil is a thiolated uracil derivative that is a known antihyperthyroid agent.
In vitro

2-Thiouracil is an established antithyroid drug and an extensively investigated agent for the early detection and targeting of metastatic melanotic melanoma. In addition, 2-Thiouracil is also a selective inhibitor of neuronal nitric oxide synthase antagonising tetrahydrobiopterin-dependent enzyme activation and dimerization.

In vivo

Cell Data

cell lines：EOL-1 cell line

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Sinonimi

2-thioxo-2,3-dihydropyrimidin-4(1H)-one

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

2-Thiouracil is a thiolated uracil derivative that is a known antihyperthyroid agent.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

INHIBITOR

Nomi e identificatori

• Isomeri SMILES: C1=CNC(=S)NC1=O
• WGK Germania: 3
• RTECS: YR1575000
• PubChem CID: 1269845
• Peso molecolare: 128.15
• Beilstein: 112227
• Reaxy-Rn: 112227

Proprietà chimiche e fisiche

• Punto di fusione (°C): >300°C

Riferimenti

1. Kaijie Xu, Kangping Cui, Minshu Cui, Xueyan Liu, Xing Chen.  (2022)  Carbonyl heterocycle modified mesoporous carbon nitride in photocatalytic peroxydisulfate activation for enhanced ciprofloxacin removal: Performance and mechanism.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:36403448] [10.1016/j.jhazmat.2022.130412]

2. Feifei Xu, Jianghong Zhao, Jianlong Wang, Taotao Guan, Kaixi Li.  (2021)  Strong coordination ability of sulfur with cobalt for facilitating scale-up synthesis of Co9S8 encapsulated S, N co-doped carbon as a trifunctional electrocatalyst for oxygen reduction reaction, oxygen and hydrogen evolution reaction.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:34794809] [10.1016/j.jcis.2021.10.182]

3. Xiaolei Zhao, Yu He, Yanan Wang, Shuo Wang, Junping Wang.  (2019)  Hollow molecularly imprinted polymer based quartz crystal microbalance sensor for rapid detection of methimazole in food samples.  FOOD CHEMISTRY,      [PMID:31771917] [10.1016/j.foodchem.2019.125787]

Domande frequenti

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 141-90-2, the molecular formula is C4H4N2OS, and the molecular weight is 128.15 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.