3-Methyladenine - ≥98% , CAS No.5142-23-4
Selective PI3K inhibitor
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Selective PI3K inhibitor
3-Methyladenine is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM; blocks class I PI3K consistently, whereas suppression of class III PI3K is transient, and also blocks autophagosome formation.
A multi-use inhibitor that protects cerebellar granule cells from apoptosis.
| CAS | 5142-23-4 |
|---|---|
| Sinonimi | 3-MA | 3-methyl-3H-purin-6-amine (ACD/Name 4.0) | 3-Methyl-3H-purin-6-amine # | Purine, 3,6-dihydro-6-imino-3-methyl- | AC-28818 | FSASIHFSFGAIJM-UHFFFAOYSA-N | HY-19312 | W-202935 | 3899G64TKW | 3-Methyl-3H-adenine | 3-methyl-3H-purin-6-ylamine (ACD/Name |
| Specifiche e purezza | ≥98% |
| Condizioni di conservazione di stoccaggio | Room temperature |
| Spedito in | Normal |
| Product Description | 3-Methyladenine is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM; blocks class I PI3K consistently, whereas suppression of class III PI3K is transient, and also blocks autophagosome formation. |
| Pubchem Sid | 508809037 |
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/508809037 |
| Solubilità | Soluble in DMSO (10 mg/ml), water (5 mg/ml), DMF (10 mg/ml), 95% ethanol, and 1N NaOH heating (30 mg/ml). |
| Numero Mdl | MFCD00010531 |
| Numero CE | 225-908-6 |
| PubChem CID | 135398661 |
| Formula molecolare | C6H7N5 |