4FBII - ≥98% , CAS No.887623-88-3

CAS: 887623-88-3 Cat. No.: F1333533 Formula: C₇H₈FIN₂ Peso molecolare: 266.05

GRADE & PURITY ≥98%

Storage

Store at 2-8°C,Protected from light,Argon charged

Shipped In

Wet ice

Specifications

Specifiche e purezza

≥98%

Condizioni di conservazione di stoccaggio

Store at 2-8°C,Protected from light,Argon charged

Spedito in

Wet ice

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥98%

Nomi e identificatori

Peso molecolare

266.05

Proprietà chimiche e fisiche

• Sensibilità: Light sensitive；Moisture sensitive；Air sensitive

Application Protocols

No tested application protocols are provided for this SKU.

General best practices (not product-specific):

• Upon receipt, document batch/lot, store immediately at 2–8°C protected from light, and maintain the argon blanket. Allow to equilibrate to handling temperature under inert gas before opening to avoid condensation.
• If preparing solutions, use anhydrous, oxygen-free solvents and amber vials. Record concentration, solvent, and preparation date; re-cap under inert gas.
• Validate performance on a small scale in the intended workflow (materials modification, synthesis, or analysis), and confirm integrity by analytical methods (e.g., LC/MS, NMR) before critical experiments.

Please consult the product’s CoA/SDS for any method-specific recommendations if available.

Biological Roles

Not applicable for this listing without a disclosed structure and function. No biological role, pathway, or mechanistic information can be ascribed to this SKU from the available Product Data.

• Research Use Only: The product is designated for research use only and is not intended for diagnostic, therapeutic, or clinical applications.
• If the compound is intended for bio-related materials work (e.g., surface functionalization, conjugation), consult the detailed specification sheet for structure, purity, endotoxin/bioburden (if relevant), and any buffer/aqueous compatibility before introducing into biological systems.

Please refer to the CoA/SDS for authoritative information and evaluate biological relevance only after confirming identity.

Buffer Applications

Specific buffer systems, pH ranges, and recipes cannot be recommended without the compound’s identity and pKa profile.

• If aqueous use is anticipated, perform a small-scale stability test across candidate buffers (e.g., phosphate, HEPES, acetate) at intended pH and temperature, monitoring for hydrolysis, oxidation, or photolysis, especially since the item is stored protected from light under argon.
• Avoid assumptions about metal-ion compatibility and salt effects until stability is confirmed by analytical methods (LC/MS, UV-Vis, NMR).

Conclusion: Buffer applications are not typically assigned without known structure. Consult the CoA and run exploratory stability assays prior to use in buffered media.

Green Alternatives

Because the exact identity and process role of this item are not disclosed, green-alternative guidance must remain general (not product-specific):

• Prefer greener solvents where functionally suitable: replace DMF/NMP with MeCN, 2-MeTHF, CPME, EtOAc, or propylene carbonate when compatible with the chemistry and stability profile.
• Minimize halogenated solvents (e.g., DCM) in favor of EtOAc, MeTHF, CPME, or supercritical CO2 extraction where viable.
• Use catalytic rather than stoichiometric reagents when feasible, and select benign bases (e.g., carbonate) or aqueous biphasic systems if the compound tolerates water.
• Optimize energy input: consider room-temperature or photoredox/electrochemical methods only if the compound is not light-sensitive. Given the light-protection note for this product, avoid photochemical steps unless validated.

Illustrative comparison (generic):

• THF → 2-MeTHF: similar solvent power, higher boiling point, bio-based feedstock, improved safety for peroxides but still monitor.
• DCM → EtOAc/MTBE/CPME: reduces halogenated waste; check selectivity and phase behavior.
• DMF/NMP → MeCN/PC/DMSO: lower toxicity profiles in some cases and easier workup; verify solubility/reactivity and stability.

Action point: Confirm the compound’s stability and solubility envelope (from CoA/literature) before substituting solvents or conditions to ensure product integrity and yield.

Pharmaceutical Uses

No pharmacopeial status, excipient role, or formulation guidance is provided for this SKU.

• Without a disclosed identity, no claims can be made regarding compliance with pharmacopeial monographs (USP/EP/JP) or suitability as an excipient or processing aid.
• If the material is to be evaluated in formulation research, first obtain the full specification (identity, purity, residual solvents, stabilizers, trace metals) and assess compatibility with intended dosage forms in a preclinical research setting only.

Note: This product is for research use only and is not intended for human or veterinary use, clinical investigation, or diagnostic procedures.

Physical Properties

Item-specific physical constants are not disclosed in the Product Data.

• Appearance: Not specified for this item; refer to CoA/Spec Sheet.
• Melting point / Boiling point: Not specified for this item; refer to CoA/Spec Sheet.
• Density: Not specified for this item; refer to CoA/Spec Sheet.
• Refractive index: Not specified for this item; refer to CoA/Spec Sheet.
• Solubility profile: Not specified for this item; refer to CoA/Spec Sheet.
• LogP, pKa: Not specified for this item; refer to CoA/Spec Sheet.

General guidance (non-item-specific):

• Because the product is stored at 2–8°C and protected from light under argon, it may contain moieties that are sensitive to oxygen/moisture and/or photolabile. In such cases, materials may be handled under inert atmosphere with anhydrous solvents to preserve purity (general practice; not product-specific).
• If the item is a low-volatility solid, handle as a dry powder under inert gas; if an oil or solution, minimize headspace air exposure and re-seal under argon. Verify with actual item documentation.

Always rely on the item’s CoA/SDS for authoritative specifications before use, especially for drying, solvent choice, and temperature limits.

Quality and Grades

• Grade/Purity: Not specified for this item; refer to CoA/Spec Sheet.
• Stabilizers/additives: Not specified for this item; refer to CoA/Spec Sheet.

Interpretation and implications (general guidance):

• When grade and purity are unspecified, consult the CoA for assay (%), residual solvents, water content, and chromatographic identity tests. Confirm fitness for purpose (analytical, synthetic, or materials processing) prior to scale-up.
• Low UV-absorbance or HPLC grades are typically needed for chromatographic or photochemical studies; materials bearing photosensitive groups may also include specific stabilizers—none are indicated here for this SKU.
• For moisture/oxygen-sensitive materials, suppliers sometimes package under inert gas with desiccants or light-blocking containers. This item is argon-charged and light-protected, suggesting sensitivity; ensure these controls are maintained after opening.
• If regulatory or method-specific grades (e.g., ACS, AR, electronic grade, semiconductor grade) are required for your process, verify explicitly; do not infer from the present listing.

Recommendation: Request the latest batch CoA and specification sheet for confirmation of assay, impurity profile, stabilizers, and any application-relevant tests (e.g., trace metal content, residual monomer, endotoxin) before critical use.

Reaction and Applications

Manufacturer Applications: Not specified in the Product Data for this SKU.

General considerations for materials-science reagents (not item-specific):

• Functional small molecules and linkers are commonly applied in surface modification, polymer end-group installation, thin-film fabrication, and bio-conjugation workflows. Exact suitability depends on the functional groups present, which are not disclosed here.
• If the reagent is oxygen- or light-sensitive (consistent with argon-charged, light-protected storage), reactions should be planned under inert atmosphere with dry solvents, limiting exposure during setup, sampling, and workup.
• For potential coupling applications: choose coupling strategies (carbodiimide, NHS ester, click-type, imine/hydrazone/oxime formation) only after confirming the actual functional handles from the specification sheet. Avoid assuming compatibility.
• Analytical verification: establish a small-scale feasibility run and verify product identity by orthogonal methods (e.g., LC/MS, NMR, IR), and monitor for decomposition.

Scale-up guidance:

• Optimize equivalents and concentration ranges at milligram scale before gram-scale implementation.
• Calibrate quench and workup to avoid exposure to air/light if sensitivity is confirmed.

Please obtain definitive structural and reactivity information (CoA/SDS/application note) prior to designing reactions.

Reaction Conditions

No item-specific reaction conditions, catalysts, or yields are provided.

General guidance for sensitive materials (not product-specific):

• Atmosphere: Conduct reactions under nitrogen/argon with degassed solvents when oxygen/moisture sensitivity is suspected.
• Temperature: Begin at ambient temperature and adjust cautiously; perform calorimetric checks at small scale when exotherms are possible.
• Solvents: Select based on solubility and stability screens; favor dry, oxygen-free solvents. Use amberware if light sensitivity is indicated.
• Workup: Quench under controlled conditions; avoid strong acids/bases or nucleophiles until compatibility is known. Minimize light/air exposure during extractions and evaporations.
• Monitoring: Use in situ IR, TLC, or LC/MS with rapid sampling to limit exposure.

Expected yields and kinetics cannot be generalized without structural information. Always validate with a small-scale proof-of-concept before scale-up.

Safety and Handling

Safety data specific to this SKU are not provided in the listing and must be confirmed from the SDS.

• GHS classification: Not specified for this item; refer to SDS.
• Signal word / Pictograms / H-statements: Not specified for this item; refer to SDS.

General laboratory precautions (not product-specific):

• Personal protective equipment: lab coat, safety glasses, and appropriate chemically resistant gloves. Work in a fume hood to avoid inhalation of vapors/particulates.
• Inert-atmosphere handling: The product is supplied argon-charged and should be kept protected from air and light. Purge containers with inert gas after each use. Avoid repeated warming/cooling cycles that introduce moist air.
• Incompatibilities: Without specific structure, avoid strong oxidizers/reducers, strong acids/bases, and nucleophiles until compatibility is known. Do not expose to UV/strong light if listed as light-sensitive.
• First aid (overview): In case of skin/eye contact, rinse with water for at least 15 minutes; remove contaminated clothing. If inhaled, move to fresh air. If swallowed, rinse mouth. Seek medical attention in all cases. Follow your institution’s protocols.
• Spill response: Contain, avoid dust/vapor formation, and collect using inert absorbent. Dispose according to institutional and regulatory requirements.

Always defer to the SDS and institutional risk assessment for specific hazards, exposure limits, and response procedures.

Solvent Selection

Item-specific solubility data are not provided. The following framework can help plan a rational solvent screen under inert conditions (general guidance; not product-specific):

• Start with anhydrous polar aprotic solvents: DMSO, DMF, NMP, and acetonitrile often dissolve polar/functionalized organics. Maintain water content as low as practical when the substance is moisture-sensitive.
• Evaluate moderately polar/etheric media: THF, 2-MeTHF, CPME, and dioxane may provide good solubility for many small molecules and are amenable to inert-atmosphere handling.
• Check less polar options: Ethyl acetate, toluene, and dichloromethane for neutral organics. Verify light sensitivity and avoid prolonged light exposure during dissolution if applicable.
• Aqueous compatibility: Without structure, aqueous solubility and buffer compatibility cannot be assumed. If aqueous work is necessary, prepare small test solutions, adjust pH cautiously, and monitor for hydrolysis/decomposition.

Practical tips:

• Perform a tiered solubility screen at room temperature and, if safe, at mild warming (e.g., 30–40°C) under argon, assessing clarity and stability over time and light exposure.
• Use amber vials/syringes if light-sensitive; backfill headspace with inert gas after sampling.
• Document solvent histories and any observed degradation (color change, gas evolution, precipitate) to refine storage and use.

Consult the CoA/SDS for any explicit solvent restrictions before committing to a process.

Storage and Reconstitution

Item-specific storage conditions are provided and should be strictly followed to maintain integrity.

• Storage (as provided): Store at 2–8°C, protected from light, argon charged.
• Shipping: Shipped on wet ice to preserve material stability.

Practical guidance:

• Keep the container tightly sealed. Open only in a dry, inert atmosphere (e.g., glove box or using Schlenk techniques) to maintain the argon blanket and minimize moisture/oxygen ingress.
• After each use, purge the headspace with argon, re-seal promptly, and return to 2–8°C storage. Use amber vials or secondary light shielding if repackaging.
• Reconstitution: Solvent choice is not specified for this item; refer to CoA/Spec Sheet. If a solution is required, prepare with anhydrous, oxygen-free solvent under inert gas. Filter through a small PTFE syringe filter if particulate is present and compatible. Record concentration and date; consider aliquoting to minimize freeze–thaw or repeated air exposure.
• Stability/expiry: Not specified for this item; refer to CoA/Spec Sheet. Monitor for signs of degradation (color change, precipitation, gas evolution) and discard if compromised.

Always consult the product’s SDS and CoA for definitive storage limits, compatible solvents, and handling precautions.

Structure and Identity

Brief overview: This SKU (F1333533, product name “4FBII”) is listed under Materials Science. The listing does not include a disclosed structure.

• CAS: 887623-88-3
• Chemical name: Not specified for this item; refer to CoA/Spec Sheet.
• Molecular formula: Not specified for this item; refer to CoA/Spec Sheet.
• Molecular weight: Not specified for this item; refer to CoA/Spec Sheet.
• SMILES: Not specified for this item; refer to CoA/Spec Sheet.
• InChI / InChIKey: Not specified for this item; refer to CoA/Spec Sheet.
• Synonyms/trade names: Product name “4FBII” only in this listing.

Structural features (general note):

• Item-specific functional groups, ring systems, and stereochemistry are not provided in the Product Data. Do not assume identity or equivalence to similarly named reagents.
• Some literature uses “4FB” as shorthand for aldehyde-bearing linkers; however, the specific identity and structure for this SKU are not disclosed here (literature note; not product-specific).

2D structure description:

• Not available for this item. Please consult the Certificate of Analysis (CoA) or detailed specification sheet for definitive structural information before planning synthetic or application workflows.

Synthetic Utility

Item-specific synthetic roles (functional group interconversions, named-reaction applicability, or crosslinking behavior) cannot be detailed without a disclosed structure.

General planning notes (not product-specific):

• Confirm the exact functional groups and protecting/stabilizing features by CoA and, if needed, by independent NMR/IR/MS before committing to route design.
• If the substance is air/light sensitive (as storage suggests), plan manipulations under inert atmosphere with dry glassware and anhydrous solvents. Minimize exposure during transfers and workup.
• Establish an analytical baseline (HPLC/GC, LC/MS, 1H/13C NMR) upon receipt to track stability during method development.
• If the reagent is a coupling handle or linker, pre-screen coupling conditions (base, catalyst, solvent) on micro- to millimole scale and verify selectivity versus self-reaction or decomposition.

Action: Acquire the full specification sheet for reliable retrosynthetic analysis and reaction planning.

Target Specificity

Not applicable. This product is not an antibody, enzyme, probe, or targeted biological reagent in the provided listing.

• No antigen/epitope, species reactivity, clone, or isotype information is available.
• If the material is intended as a chemical probe in your research, verify identity and purity from the CoA, and establish target engagement using appropriate biochemical/biophysical assays designed for your system.