5-Ethynyluridine (5-EU) - ≥99% , CAS No.69075-42-9

CAS: 69075-42-9 Cat. No.: E276476 Formula: C₁₁H₁₂N₂O₆ Peso molecolare: 268.22

QUALITÀ & PUREZZA ≥99%

Synonyms

5-EU | AKOS024462949 | 5-ethynyl uridine | DS-8002 | EX-A3665 | GLXC-25273 | AC-32359 | QCWBIPKYTBFWHH-FDDDBJFASA-N | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-ethynylpyrimidine-2,4-dione | 5-Ethynyl Uridine (EU) | C76184 | Uridine, 5

Storage

Protected from light,Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

Panoramica

Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.

Specifiche

Sinonimi

5-EU | AKOS024462949 | 5-ethynyl uridine | DS-8002 | EX-A3665 | GLXC-25273 | AC-32359 | QCWBIPKYTBFWHH-FDDDBJFASA-N | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-ethynylpyrimidine-2,4-dione | 5-Ethynyl Uridine (EU) | C76184 | Uridine, 5

Specifiche e purezza

≥99%

Meccanismi biochimici e fisiologici

Uridine analog. Click chemistry RNA transcription label. Incorporates into RNA during active RNA synthesis. Does not incorporate into DNA. Reacts with azide-containing detection reagents.

Condizioni di conservazione di stoccaggio

Protected from light,Store at -20°C,Argon charged,Desiccated

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purezza

≥99%

Nomi e identificatori

Pubchem Sid

488198755

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488198755

Sorrisi canonici

C#CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-ethynylpyrimidine-2,4-dione

InChIKey

QCWBIPKYTBFWHH-FDDDBJFASA-N

INCHI

1S/C11H12N2O6/c1-2-5-3-13(11(18)12-9(5)17)10-8(16)7(15)6(4-14)19-10/h1,3,6-8,10,14-16H,4H2,(H,12,17,18)/t6-,7-,8-,10-/m1/s1

Isomeri SMILES

C#CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O

Peso molecolare

268.22

Reaxy-Rn

25709386

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25709386&ln=

Obiettivi associati (non umani)

Pseudomonas aeruginosa (123386 Activities)

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Salmonella typhimurium (15756 Activities)

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Staphylococcus aureus (210822 Activities)

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Escherichia coli (133304 Activities)

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Mycobacterium avium (4587 Activities)

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Mycobacterium tuberculosis (203094 Activities)

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Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: Soluble in PBS and water to 200 mM (with heating)
• Sensibilità: air sensitive; light sensitive;Moisture sensitive
• Punto di fusione (°C): 190℃
• Peso molecolare: 268.220 g/mol
• XLogP3: -1.700
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 268.07 Da
• Monoisotopic Mass: 268.07 Da
• Topological Polar Surface Area: 119.000 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 493.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1