≥98% (HPLC) per flussi di lavoro cromatografici e analitici sensibili che richiedono un'interferenza minima della linea di base.
Room temperature Spedizione Normale. Consultare il COA specifico del lotto per le specifiche esatte.
SDS, COA, scheda tecnica e scheda delle specifiche disponibili per il download. COA specifico del lotto accessibile tramite ricerca per numero di lotto.
Citato in 0 pubblicazioni peer-reviewed su cromatografia, sintesi organica e reazioni di accoppiamento incrociato.
il 6(5H)-Fenantridinone è una piccola molecola inibitrice della poli(ADP-ribosio) polimerasi (PARP) con effetti immunosoppressivi. è stato dimostrato che il 6(5H)-Fenantridinone inibisce la proliferazione dei linfociti indotta dalla concanavilina A, producendo l'attività immunosoppressiva osservata di questo composto. È stato inoltre dimostrato che potenzia l'effetto delle radiazioni ionizzanti sulle cellule in via di sviluppo, aumentando fortemente l'inibizione della proliferazione cellulare indotta dalle radiazioni, il che suggerisce l'uso del 6(5H)-Fenantridinone come sonda del ruolo di PARP nella risposta cellulare alle radiazioni. Il trattamento delle cellule con 6(5H)-Fenantridinone e vari agenti dannosi per il DNA ha mostrato una resistenza all'apoptosi rispetto al trattamento con i soli agenti dannosi per il DNA, indicando che l'attività della PARP è coinvolta nel processo apoptotico.
Reagente coinvolto in: Sintesi di 5,6-diidrofenantridina sulfonamidi. Accoppiamento ossidativo con difenilacetilene. N-ciclopropilazione diretta di ammidi cicliche catalizzata da acetato di rame. Reagente coinvolto nella sintesi e/o nell'attività farmacologica di molecole biologicamente attive, tra cui: Inibitori dei canali del potassio KV1.3 e IK-1. Inibitori dell'integrasi dell'HIV-1.
Documento completo su pericoli, manipolazione, stoccaggio e conformità normativa.
<<<<<<< HEAD Scarica SDS → ======= Scarica SDS → >>>>>>> release248-p3Dati di qualità specifici del lotto. Inserisci il numero di lotto per recuperare il COA esatto.
Cerca COA →Riepilogo di riferimento rapido delle specifiche e applicazioni del prodotto.
Visualizza scheda tecnica →Attributi di qualità completi e criteri di accettazione per questa qualità.
Visualizza scheda delle specifiche →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Classe | Quinolines and derivatives |
| Subclass | Benzoquinolines |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Phenanthridines and derivatives |
| Alternative Parents | Quinolones and derivatives Isoquinolines and derivatives Hydroxypyridines Benzenoids Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Phenanthridine - Quinolone - Isoquinoline - Hydroxypyridine - Benzenoid - Pyridine - Heteroaromatic compound - Azacycle - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic heteropolycyclic compound |
| Descrizione | This compound belongs to the class of organic compounds known as phenanthridines and derivatives. These are polycyclic compounds containing a phenanthridine moiety, which is a tricyclic system with two benzene rings joined by a pyridine forming a non-linear skeleton. Hydrogenated derivatives are also included. |
| External Descriptors | phenanthridines - lactam |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Data | Oggetto |
|---|---|---|---|
 I2404508 | Certificate of Analysis | Jun 15, 2026 | H137937 |
| B2221126 | Certificate of Analysis | Sep 09, 2025 | H137937 |
| B2221144 | Certificate of Analysis | Sep 09, 2025 | H137937 |
| B2221161 | Certificate of Analysis | Sep 09, 2025 | H137937 |
| B2219157 | Certificate of Analysis | Dec 14, 2023 | H137937 |
| D1719140 | Certificate of Analysis | Nov 16, 2022 | H137937 |
| Punto di fusione (°C) | 288-294℃ |
|---|---|
| Peso molecolare | 195.220 g/mol |
| XLogP3 | 2.500 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 0 |
| Exact Mass | 195.068 Da |
| Monoisotopic Mass | 195.068 Da |
| Topological Polar Surface Area | 29.100 Ų |
| Heavy Atom Count | 15 |
| Formal Charge | 0 |
| Complexity | 263.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
