7-Ketocholesterol - Moligand™, 10 mM in DMSO , CAS No.566-28-9

CAS: 566-28-9 Cat. No.: K1494769 Formula: C₂₇H₄₄O₂ Peso molecolare: 400.64

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

7-Ketocholesterol is an oxidation product of cholesterol , widely present in atherosclerotic plaques, and has a stronger atherogenic effect than cholesterol . 7-Ketocholesterol can inhibit the rate-limiting enzymes involved in bile acid and cholesterol synthesis, such as cholesterol 7α-hydroxylase and HMG-CoA reductase . 7-Ketocholesterol exhibits pro-inflammatory effects both in vivo and in vitro and can induce cell apoptosis ( apoptosis ).

Specifications

Specifiche e purezza

Moligand™, 10 mM in DMSO

Condizioni di conservazione di stoccaggio

Protected from light,Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Tipo di azione

ACTIVATOR

Nomi e identificatori

• Isomeri SMILES: C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C(=O)C=C4[C@@]3(CC[C@@H](C4)O)C)C
• WGK Germania: 3
• Peso molecolare: 400.64
• Reaxy-Rn: 2063124
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2063124&ln=

Riferimenti

1. Yueyuan Zhang, Sha Xu, Jianxin Xu, Fuchao Xu, Geng Lu, Jiawei Zhou, Shuangshuang Gu, Jun Wang.  (2023)  Prognostic value of plasma 7-ketocholesterol in sepsis.  CLINICA CHIMICA ACTA,      [PMID:37399884] [10.1016/j.cca.2023.117467]

2. Ge Bai, Chuan-Guo Ma, Yu-Yuan Hu, Shu-Jing Guo, Tong Wang.  (2023)  Chemical conversions of free phytosterols during the bleaching of corn oil.  FOOD CHEMISTRY,      [PMID:36731234] [10.1016/j.foodchem.2023.135512]

3. SunHongzheng , HanLongsen , GuoYueshuai , AnHuiqing , WangBing , ZhangXiangzheng , LiJiashuo , JiangYingtong , WangYue , SunGuangyi , ZhuShuai , TangShoubin , GeJuan , ChenMinjian , GuoXuejiang , WangQiang.  (2024)  The global phosphorylation landscape of mouse oocytes during meiotic maturation.  EMBO JOURNAL,      [PMID:39256562] [10.1038/s44318-024-00222-1]

Domande frequenti

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 566-28-9, the molecular formula is C27H44O2, and the molecular weight is 400.64 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.