8-Bromo-cAMP - 10mM in DMSO , CAS No.76939-46-3

CAS: 76939-46-3 Cat. No.: B407933 Formula: C₁₀H₁₀BrN₅NaO₆P Peso molecolare: 430.08

GRADE & PURITY 10mM in DMSO

Synonyms

8-Br-Camp | 8-bromoadenosine 3',5'-cyclic monophosphate sodium salt

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Information

8-Bromo-cAMP 8-bromo-cAMP (8-Br-Camp) is a cell permeable analog of cAMP that activates cyclic-AMP-dependent protein kinase with a Ka value of 0.05 μM; and a PKA activator.
In vitro

8-Bromo-cAMP improves the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells. In bronchial epithelial cells, 8-Bromo-cAMP decreases HDE-stimulated tumor necrosis factor (TNF)-α-converting enzyme (TACE; ADAM-17) activity and subsequent TNF-α release.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Sinonimi

8-Br-Camp | 8-bromoadenosine 3',5'-cyclic monophosphate sodium salt

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

8-bromo-cAMP (8-Br-Camp) is a cell permeable analog of cAMP that activates cyclic-AMP-dependent protein kinase with a Ka value of 0.05 μM; and a PKA activator.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Nomi e identificatori

• Isomeri SMILES: C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C4=NC=NC(=C4N=C3Br)N)O)OP(=O)(O1)[O-].[Na+]
• Peso molecolare: 430.08
• Reaxy-Rn: 26039674
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=26039674&ln=

Domande frequenti

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 76939-46-3, the molecular formula is C10H10BrN5NaO6P, and the molecular weight is 430.08 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.