A 804598 - Moligand™, 10mM in DMSO , Antagonist of P2X7, CAS No.1125758-85-1, Antagonist of P2X7

CAS: 1125758-85-1 Cat. No.: A420653 Formula: C19H17N5 Peso molecolare: 315.37 Numero EC: 802-550-4
Disponibile su ordine
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Synonyms
N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine;A-804598;N-Cyano-N′′-[(1S)-1-phenylethyl]-N′-5-quinolinyl-guanidine
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Germania (EU)
USA*
Price
Qty
1ml
A420653-1ml
—
2 Disponibile

134,41€

196,89€
Salva 62,48 € (31.73%)
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Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinonimi
N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine;A-804598;N-Cyano-N′′-[(1S)-1-phenylethyl]-N′-5-quinolinyl-guanidine
Specifiche e purezza
Moligand™, 10mM in DMSO
Meccanismi biochimici e fisiologici
Potent, competitive P2X7receptor antagonist (IC50values are 8.9, 9.9 and 10.9 nM for mouse, rat and human P2X7receptors respectively). Selective for P2X7receptors (IC50> 5-10μM for a wide array of cell surface receptors and ion channels). Binds with high
Condizioni di conservazione di stoccaggio
Store at -80°C
Spedito in
Dry ice packs + Cold packs
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Grado
Moligand™
Tipo di azione
ANTAGONIST
Meccanismo d'azione
Antagonist of P2X7
Nomi e identificatori
Pubchem Sid528762980
Sorrisi canoniciCC(C1=CC=CC=C1)N=C(NC#N)NC2=CC=CC3=C2C=CC=N3
IUPAC Name1-cyano-2-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine
InChIKeyPQYCRDPLPKGSME-AWEZNQCLSA-N
INCHI1S/C19H17N5/c1-14(15-7-3-2-4-8-15)23-19(22-13-20)24-18-11-5-10-17-16(18)9-6-12-21-17/h2-12,14H,1H3,(H2,22,23,24)/t14-/m0/s1
Isomeri SMILES C[C@@H](C1=CC=CC=C1)N=C(NC#N)NC2=CC=CC3=C2C=CC=N3
Peso molecolare 315.37
Reaxy-Rn 31636225
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=31636225&ln=

Documentazione

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Struttura 3D
Modello di struttura chimica interattiva





Obiettivi associati (umani)
P2RX7 Tchem P2X purinoceptor 7 (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Proprietà chimiche e fisiche
Peso molecolare315.400 g/mol
XLogP34.000
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Exact Mass315.148 Da
Monoisotopic Mass315.148 Da
Topological Polar Surface Area73.100 Ų
Heavy Atom Count24
Formal Charge0
Complexity473.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calcolatori di soluzioni
Recensioni

Recensioni dei clienti

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