AC 1903 - Moligand™, ≥98% (HPLC) , Channel blocker of TRPC5, CAS No.831234-13-0, Channel blocker of TRPC5

CAS: 831234-13-0 Cat. No.: A287610 Formula: C19H17N3O Peso molecolare: 303.36 Numero EC: 820-119-9
Disponibile su ordine
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
Synonyms
EX-A4021 | 1-benzyl-N-(furan-2-ylmethyl)-1H-benzimidazol-2-amine | cid_667146 | VU0217898-5 | N-(1-BENZYL-1H-1,3-BENZIMIDAZOL-2-YL)-N-(2-FURYLMETHYL)AMINE | (1-benzylbenzimidazol-2-yl)-(2-furfuryl)amine | SCHEMBL22619593 | BDBM49021 | AC 1903 | D95158 | E
Storage
Conservare a -20°C
Shipped In
Cassetta del ghiaccio + cuscini per il ghiaccio
★
Size
Germania (EU)
USA*
Price
Qty
5mg
A287610-5mg
—
3 Disponibile

38,09€

57,18€
Salva 19,09 € (33.38%)
10mg
A287610-10mg
—
3 Disponibile

55,45€

83,22€
Salva 27,77 € (33.37%)
25mg
A287610-25mg
—
2 Disponibile

93,63€

140,49€
Salva 46,86 € (33.35%)
50mg
A287610-50mg
—
2 Disponibile

158,71€

238,54€
Salva 79,83 € (33.47%)
100mg
A287610-100mg
Su ordinazione · 8–12 settimane

270,65€

406,02€
Salva 135,37 € (33.34%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Moligand™, ≥98% (HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Conservare a -20°C Ships Cassetta del ghiaccio + cuscini per il ghiaccio Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Panoramica

AC1903 è stato utilizzato come candidato farmaco in un saggio di formazione di colonie in agar ad alto rendimento per identificare la sua efficacia terapeutica contro il medulloblastoma.

Specifications

Sinonimi
EX-A4021 | 1-benzyl-N-(furan-2-ylmethyl)-1H-benzimidazol-2-amine | cid_667146 | VU0217898-5 | N-(1-BENZYL-1H-1,3-BENZIMIDAZOL-2-YL)-N-(2-FURYLMETHYL)AMINE | (1-benzylbenzimidazol-2-yl)-(2-furfuryl)amine | SCHEMBL22619593 | BDBM49021 | AC 1903 | D95158 | E
Specifiche e purezza
Moligand™, ≥98% (HPLC)
Meccanismi biochimici e fisiologici
Bloccante selettivo della TRPC5 (IC50= 13,6 μM). Mostra anche una debole inibizione della TRPC4 (IC50>100 μM) ma non della TRPC6. Non mostra alcun effetto nei confronti di un pannello standard di chinasi di profilazione. Blocca l'attività del canale TRPC5
Condizioni di conservazione di stoccaggio
Conservare a -20°C
Spedito in
Cassetta del ghiaccio + cuscini per il ghiaccio
Grado
Moligand™
Tipo di azione
CHANNEL BLOCKER
Meccanismo d'azione
Channel blocker of TRPC5
Purezza
≥98%(HPLC)
Nomi e identificatori
Pubchem Sid504759804
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504759804
Sorrisi canoniciC1=CC=C(C=C1)CN2C3=CC=CC=C3N=C2NCC4=CC=CO4
IUPAC Name1-benzyl-N-(furan-2-ylmethyl)benzimidazol-2-amine
InChIKeyOECUWHDVQIITIS-UHFFFAOYSA-N
INCHI1S/C19H17N3O/c1-2-7-15(8-3-1)14-22-18-11-5-4-10-17(18)21-19(22)20-13-16-9-6-12-23-16/h1-12H,13-14H2,(H,20,21)
Isomeri SMILES C1=CC=C(C=C1)CN2C3=CC=CC=C3N=C2NCC4=CC=CO4
Peso molecolare 303.36
Reaxy-Rn 32139785
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=32139785&ln=

Documentazione

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClasseBenzimidazoles
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentBenzimidazoles
Alternative Parents Secondary alkylarylamines  N-substituted imidazoles  Benzene and substituted derivatives  Aminoimidazoles  Heteroaromatic compounds  Furans  Oxacyclic compounds  Azacyclic compounds  Organopnictogen compounds  Organooxygen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Benzimidazole - Secondary aliphatic/aromatic amine - Aminoimidazole - Monocyclic benzene moiety - Benzenoid - N-substituted imidazole - Azole - Heteroaromatic compound - Furan - Imidazole - Oxacycle - Azacycle - Secondary amine - Organic nitrogen compound - Amine - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
DescrizioneThis compound belongs to the class of organic compounds known as benzimidazoles. These are organic compounds containing a benzene ring fused to an imidazole ring (five member ring containing a nitrogen atom, 4 carbon atoms, and two double bonds).
External Descriptors Not available
Struttura 3D
Modello di struttura chimica interattiva





Obiettivi associati (umani)
TRPC5 Tchem Short transient receptor potential channel 5 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TRPC5 Tchem Short transient receptor potential channel 5 (300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Obiettivi associati (non umani)
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NS1 Nonstructural protein 1 (33327 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Meccanismi d'azione
Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDataOggetto
C2211327Certificate of AnalysisDec 17, 2024 A287610
C2211328Certificate of AnalysisDec 17, 2024 A287610
C2211329Certificate of AnalysisDec 17, 2024 A287610
C2211330Certificate of AnalysisDec 17, 2024 A287610
C2211331Certificate of AnalysisDec 17, 2024 A287610
Proprietà chimiche e fisiche
SolubilitàSolvent:DMSO, Max Conc. mg/mL: 15.17, Max Conc. mM: 50
Peso molecolare303.400 g/mol
XLogP33.900
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Exact Mass303.137 Da
Monoisotopic Mass303.137 Da
Topological Polar Surface Area43.000 Ų
Heavy Atom Count23
Formal Charge0
Complexity372.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calcolatori di soluzioni
Recensioni

Recensioni dei clienti

Domande frequenti

What is the purity of this product, and how is it determined?
This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.
What is Moligand??
Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 831234-13-0, the molecular formula is C19H17N3O, and the molecular weight is 303.36 g/mol. InChIKey OECUWHDVQIITIS-UHFFFAOYSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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