Acesulfame K - Moligand™, ≥98% , CAS No.55589-62-3

CAS: 55589-62-3 Cat. No.: A113942 Formula: C₄H₄KNO₄S Peso molecolare: 201.24 Beilstein Registry Number: 3637857 Numero EC: 259-715-3

QUALITÀ & PUREZZA Moligand™, ≥98%

Synonyms

4-(1H-Tetrazol-1-yl)benzoic acid, AldrichCPR | INS-950 | 1-Phenyl-3-(pyridin-3-yl)urea | Acesulfame potassium, European Pharmacopoeia (EP) Reference Standard | AKOS001874366 | NCGC00259972-01 | AKOS016015051 | AMY13647 | Acesulfame potassium (NF) | FT-062

Storage

Temperatura ambiente

Shipped In

Normale

Panoramica

L'acesulfame di potassio è un dolcificante sintetico. L'uso a lungo termine di acesulfame di potassio può influire sulla funzione cognitiva, probabilmente alterando le funzioni neurometaboliche nei topi. L'acesulfame di potassio può sopprimere la degradazione autofagica di PD-L1 nelle cellule RIL-175 e SK-Hep1 attraverso la via ERK1/2-mTORC1-ULK1, che può essere correlata all'evasione immunitaria nelle cellule tumorali. L'acesulfame di potassio può essere utilizzato nella ricerca sulle malattie neurologiche, sui disturbi metabolici, sul cancro e sull'evasione immunitaria.

Specifiche

Sinonimi

4-(1H-Tetrazol-1-yl)benzoic acid, AldrichCPR | INS-950 | 1-Phenyl-3-(pyridin-3-yl)urea | Acesulfame potassium, European Pharmacopoeia (EP) Reference Standard | AKOS001874366 | NCGC00259972-01 | AKOS016015051 | AMY13647 | Acesulfame potassium (NF) | FT-062

Specifiche e purezza

Moligand™, ≥98%

Meccanismi biochimici e fisiologici

Dolcificante sintetico stabile al calore. La variazione allelica del gene Tas1r3 influenza le risposte comportamentali al gusto di questa molecola, suggerendo che si tratta di un ligando del recettore T1R3.

Condizioni di conservazione di stoccaggio

Temperatura ambiente

Spedito in

Normale

Grado

Moligand™

Purezza

≥98%

Nomi e identificatori

Pubchem Sid

488197130

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488197130

Sorrisi canonici

CC1=CC(=O)[N-]S(=O)(=O)O1.[K+]

IUPAC Name

potassium;6-methyl-2,2-dioxo-1-oxa-2λ6-thia-3-azanidacyclohex-5-en-4-one

InChIKey

WBZFUFAFFUEMEI-UHFFFAOYSA-M

INCHI

1S/C4H5NO4S.K/c1-3-2-4(6)5-10(7,8)9-3;/h2H,1H3,(H,5,6);/q;+1/p-1

Isomeri SMILES

CC1=CC(=O)[N-]S(=O)(=O)O1.[K+]

WGK Germania

1

CAS alternativo

33665-90-6

Peso molecolare

201.24

Beilstein

3637857

Reaxy-Rn

3637857

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3637857&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Organic sulfuric acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Organic sulfuric acids and derivatives
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Organic sulfuric acids and derivatives
• Alternative Parents: Oxacyclic compounds Carboxylic acids and derivatives Carbene-type 1,3-dipolar compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic potassium salts Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Organic sulfuric acid or derivatives - Carboxylic acid derivative - Carbene-type 1,3-dipolar compound - Organic 1,3-dipolar compound - Organoheterocyclic compound - Organic alkali metal salt - Azacycle - Oxacycle - Organic potassium salt - Organic nitrogen compound - Organic salt - Organonitrogen compound - Organooxygen compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Aliphatic heteromonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as organic sulfuric acids and derivatives. These are organic compounds containing the sulfuric acid or a derivative thereof.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (umani)

CA2 Tclin Carbonic anhydrase II (17698 Activities)

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ESR1 Tclin Estrogen receptor alpha (17718 Activities)

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NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

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AR Tclin Androgen Receptor (11781 Activities)

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VDR Tclin Vitamin D receptor (26531 Activities)

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THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)

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CXCL8 Tchem Interleukin-8 (642 Activities)

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CA1 Tclin Carbonic anhydrase I (13240 Activities)

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CA12 Tclin Carbonic anhydrase XII (6231 Activities)

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CA9 Tclin Carbonic anhydrase IX (8255 Activities)

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TP53 Tchem Cellular tumor antigen p53 (48468 Activities)

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Lymphoblastoid cell (5959 Activities)

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KMT2A Tchem Histone-lysine N-methyltransferase MLL (17327 Activities)

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TAS2R31 Tchem Taste receptor type 2 member 31 (86 Activities)

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TAS2R14 Tchem Taste receptor type 2 member 14 (240 Activities)

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TAS2R16 Tchem Taste receptor type 2 member 16 (102 Activities)

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TAS2R4 Tchem Taste receptor type 2 member 4 (14 Activities)

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TAS2R41 Tchem Taste receptor type 2 member 41 (57 Activities)

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TAS2R60 Tchem Taste receptor type 2 member 60 (8 Activities)

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TAS2R9 Tchem Taste receptor type 2 member 9 (14 Activities)

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TAS2R10 Tchem Taste receptor type 2 member 10 (51 Activities)

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TAS2R20 Tchem Taste receptor type 2 member 20 (10 Activities)

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TAS2R50 Tchem Taste receptor type 2 member 50 (12 Activities)

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TAS2R8 Tchem Taste receptor type 2 member 8 (387 Activities)

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TAS2R38 Tchem Taste receptor type 2 member 38 (37 Activities)

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TAS2R39 Tchem Taste receptor type 2 member 39 (48 Activities)

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TAS2R40 Tchem Taste receptor type 2 member 40 (10 Activities)

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TAS2R43 Tchem Taste receptor type 2 member 43 (15 Activities)

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TAS2R45 Tchem Taste receptor type 2 member 45 (8 Activities)

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TAS2R46 Tchem Taste receptor type 2 member 46 (155 Activities)

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TAS2R30 Tchem Taste receptor type 2 member 30 (12 Activities)

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TAS2R19 Tchem Taste receptor type 2 member 19 (20 Activities)

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TAS2R42 Tchem Taste receptor type 2 member 42 (6 Activities)

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TAS2R13 Tchem Taste receptor type 2 member 13 (13 Activities)

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TAS2R7 Tchem Taste receptor type 2 member 7 (31 Activities)

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TAS2R5 Tchem Taste receptor type 2 member 5 (11 Activities)

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TAS2R3 Tchem Taste receptor type 2 member 3 (12 Activities)

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Obiettivi associati (non umani)

Mus musculus (284745 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

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SARS-CoV-2 (38078 Activities)

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Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: Soluble in water
• Sensibilità: Moisture sensitive
• Punto di fusione (°C): 229-232°C
• Peso molecolare: 201.240 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 200.95 Da
• Monoisotopic Mass: 200.95 Da
• Topological Polar Surface Area: 69.800 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 288.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Domande frequenti

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at room temperature.

How is this product shipped?

This product ships under standard ambient conditions. No temperature-controlled packaging is required.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 55589-62-3, the molecular formula is C4H4KNO4S, and the molecular weight is 201.24 g/mol. InChIKey WBZFUFAFFUEMEI-UHFFFAOYSA-M.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.