Moligand™ Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic Polymers |
| Classe | Polypeptides |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Polypeptides |
| Alternative Parents | Peptides Valine and derivatives Proline and derivatives N-acyl-L-alpha-amino acids Alpha amino acid amides Amphetamines and derivatives Pyrrolidinecarboxamides Pyrrolidine carboxylic acids N-acylpyrrolidines 1-hydroxy-2-unsubstituted benzenoids N-acyl amines Tertiary carboxylic acid amides Secondary carboxylic acid amides Amino acids Guanidines Propargyl-type 1,3-dipolar organic compounds Monocarboxylic acids and derivatives Azacyclic compounds Carboximidamides Carboxylic acids Carbonyl compounds Monoalkylamines Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Polypeptide - Alpha peptide - N-acyl-alpha-amino acid - N-acyl-l-alpha-amino acid - N-acyl-alpha amino acid or derivatives - Proline or derivatives - Valine or derivatives - Alpha-amino acid amide - Amphetamine or derivatives - Alpha-amino acid or derivatives - N-substituted-alpha-amino acid - Pyrrolidine carboxylic acid or derivatives - Pyrrolidine-2-carboxamide - N-acylpyrrolidine - Pyrrolidine carboxylic acid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Fatty acyl - Monocyclic benzene moiety - N-acyl-amine - Fatty amide - Benzenoid - Pyrrolidine - Tertiary carboxylic acid amide - Amino acid or derivatives - Amino acid - Carboxamide group - Guanidine - Secondary carboxylic acid amide - Azacycle - Organoheterocyclic compound - Organic 1,3-dipolar compound - Carboxylic acid derivative - Carboxylic acid - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Monocarboxylic acid or derivatives - Amine - Organic oxide - Carbonyl group - Hydrocarbon derivative - Organic nitrogen compound - Primary aliphatic amine - Organic oxygen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Aromatic heteromonocyclic compound |
| Descrizione | This compound belongs to the class of organic compounds known as polypeptides. These are peptides containing ten or more amino acid residues. |
| External Descriptors | Not available |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Alternate Names | ACTH (11-24) | adrenocorticotropic hormone (11-24) |
|---|---|
| Reference |
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Item-specific, validated application protocols were not provided for this product. Below are general, literature-informed procedures to guide use; adjust to your system and consult the CoA for exact concentration calculations.
General dissolution and stock preparation:
Receptor/cell-based assay example (outline):
SPR/BLI binding assay example (outline):
Analytical QC check:
These protocols are guidance only; optimize parameters for your assay and instrumentation.
Context (literature, biochemical):
Note: This information is provided for fundamental biochemical context relevant to research use. No medical/clinical claims are made or implied.
Direct use as a buffer is not applicable. ACTH-(11–24) is a peptide tool compound rather than a buffering agent.
Practical guidance for working solutions (literature, peptide-centric):
If your application requires a defined buffer recipe (e.g., for receptor binding or spectroscopy), choose the system compatible with your detection method (phosphate for UV, HEPES for fluorescence) and verify peptide stability empirically.
Peptide handling is primarily aqueous, allowing inherently greener workflows compared with many small-molecule operations. Where organic solvents are needed (e.g., to disrupt aggregates or in analytics), consider the following greener-alternative strategies.
Greener choices and trade-offs (literature guidance):
Comparison snapshot:
Operational practices:
This product is for research use only (from Product Data) and is not intended for human or veterinary use.
Formulation roles in research and development (general, non-clinical):
Practical note: Determine the peptide’s exact salt form and water content from the CoA to compute accurate dosing concentrations during non-clinical method development.
Item-specific physical constants:
Literature/computed characteristics for the ACTH-(11–24) peptide motif (informational):
Practical note: Because exact salt form (e.g., TFA, acetate), terminal modifications, and water content strongly affect mass and solubility, rely on the item’s CoA for definitive values.
Item-specific grade:
Interpretation and implications:
Use case alignment:
Applicability focus: As a bioactive peptide fragment, ACTH-(11–24) is primarily used as a tool compound rather than as a classical synthetic reagent.
Research applications (literature context):
Practical tips:
Note: Manufacturer application specifics were not provided for this item; tailor protocols to your platform and confirm peptide identity/purity via the CoA.
As a finished peptide, ACTH-(11–24) is not typically used in small-molecule reactions. However, literature provides general conditions relevant to peptide manipulation and assay deployment.
Peptide derivatization (general guidance):
Assay deployment:
SPPS context (if synthesizing analogs):
Note: The above are general conditions; item-specific reactivity data are not provided.
Item-specific hazard data (from Product Data):
General laboratory safety for research peptides (informational, defer to SDS):
Always consult the product’s SDS for authoritative hazard and response information.
Profile and miscibility (peptide-focused):
Selection tips:
Comparison to alternatives:
Compatibility:
Item-specific storage and shipping:
General best practices for peptides (informational, without contradicting item data):
Always consult the product label and CoA/SDS for item-specific instructions and stability information.
ACTH-(11-24) is a mid-sequence peptide fragment of adrenocorticotropic hormone (ACTH), commonly used as a biochemical tool in melanocortin receptor studies and peptide SAR.
Item-specific (from Product Data):
Literature identity and structural features (for ACTH-(11–24)):
Note: Exact elemental formula, mass, and any terminal modifications for this catalog item are not specified; confirm on the CoA/Spec Sheet.
While supplied as a peptide tool compound, ACTH-(11–24) is informative in peptide chemistry and can serve as:
Considerations:
Item-specific synthetic details (e.g., termini, salt form) are Not specified; consult the CoA if you plan derivative syntheses.
Not applicable. This catalog entry is a peptide tool compound, not an antibody or affinity reagent, and no target-binding specificity data are provided as item-specific specifications.
Literature context: ACTH fragments are often used to interrogate melanocortin receptor systems; however, any binding parameters (e.g., Ki, EC50) depend on sequence details, modifications, assay format, and receptor subtype. Item-specific potency/selectivity data are Not specified for this item; refer to the CoA/Spec Sheet or generate in-house under your assay conditions.
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →