Adipic acid dihydrazide（ADH） - ≥99%(HPLC) , CAS No.1071-93-8

CAS: 1071-93-8 Cat. No.: A109760 Formula: C₆H₁₄N₄O₂ Peso molecolare: 174.2 Beilstein Registry Number: 973863 Numero EC: 213-999-5

GRADE & PURITY ≥99%(HPLC)

Synonyms

Adipic acid dihydrazide, >=98% (titration) | AI3-22640 | Hexanedioic dihydrazide | J-660023 | Q-200600 | Q4682936 | Adip dihydr | AKOS000267183 | VK98I9YW5M | A801603 | Z56812730 | Adipic acid dihydrazide, purum, >=97.0% (NT) | FT-0621914 | Hexanedioic ac

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Panoramica

Homobifunctional cross-linking reagent that is specific for aldehydes resulting in relatively stable hydrazone linkages. This is commonly used in the linking of glycoproteins, such as antibodies, in a site specific fashion following periodate oxidation. Oxidation and coupling may conveniently be performed at pH 5.0 due to the low pKa of the hydrazide which avoids competition by primary amines. Note that the hydrazone bond may be stabilized by selective reduction using, for example, sodium cyanoborohydride.

General description
Adipic acid dihydrazide is a homobifunctional cross-linking reagent that is specific for aldehydes. This results in relatively stable hydrazone linkages. Adipic acid dihydrazide is generally used in the linking of glycoproteins, like antibodies, in a site-specific fashion following periodate oxidation. Oxidation and coupling may be performed at pH 5.0 due to the low pKa of the hydrazide which avoids competition by primary amines.

Specifications

Sinonimi

Adipic acid dihydrazide, >=98% (titration) | AI3-22640 | Hexanedioic dihydrazide | J-660023 | Q-200600 | Q4682936 | Adip dihydr | AKOS000267183 | VK98I9YW5M | A801603 | Z56812730 | Adipic acid dihydrazide, purum, >=97.0% (NT) | FT-0621914 | Hexanedioic ac

Specifiche e purezza

≥99%(HPLC)

Meccanismi biochimici e fisiologici

Adipic acid dihydrazide (ADH) is a low molecular weight compound that comprises a hydrazide group at each end. This leads to the supply of extra adsorption sites for heavy metals that maintain or elevate the adsorption capacities of the cross-linked adsor

Applicazione

Adipic acid dihydrazide has been used: in the preparation of reactive premix to synthesize the porous biomaterial for the crosslinking of methacrylated chondroitin sulfate (MA-CS) coating using carbodiimide-based chemistry for the production and character

Condizioni di conservazione di stoccaggio

Store at -20°C,Argon charged

Spedito in

Ice chest + Ice pads

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Purezza

≥99%(HPLC)

Nomi e identificatori

Pubchem Sid

488183736

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488183736

Sorrisi canonici

C(CCC(=O)NN)CC(=O)NN

IUPAC Name

hexanedihydrazide

InChIKey

IBVAQQYNSHJXBV-UHFFFAOYSA-N

INCHI

1S/C6H14N4O2/c7-9-5(11)3-1-2-4-6(12)10-8/h1-4,7-8H2,(H,9,11)(H,10,12)

Isomeri SMILES

C(CCC(=O)NN)CC(=O)NN

WGK Germania

3

RTECS

AV1400000

Peso molecolare

174.2

Beilstein

973863

Reaxy-Rn

973863

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=973863&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Carboxylic acid derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Carboxylic acid derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Carboxylic acid hydrazides
• Alternative Parents: Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Carboxylic acid hydrazide - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aliphatic acyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as carboxylic acid hydrazides. These are carboxylic acid derivatives containing a carbonyl group in which the carbon is directly linked to a hydrazide group (N-N).
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Proprietà chimiche e fisiche

• Solubilità: Soluble in water, alcohol and acetone.
• Sensibilità: Air Sensitive
• Punto di infiammabilità (°F): 302.0 °F
• Punto di infiammabilità (°C): 150°C
• Punto di fusione (°C): 180-182°C
• Peso molecolare: 174.200 g/mol
• XLogP3: -2.100
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 174.112 Da
• Monoisotopic Mass: 174.112 Da
• Topological Polar Surface Area: 110.000 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 142.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1