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AKR1C3-IN-9 - 10mM in DMSO , CAS No.A661699(DMSO)
AVAILABLE TO ORDER
GRADE & PURITY 10mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Why this grade
10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
AKR1C3-IN-9 is a selective inhibitor of Aldo-keto Reductase 1C3 (AKR1C3) with an IC 50 value of 8.92 nM. AKR1C3-IN-9 significantly reverses the Doxorubicin ( HY-15142A ) (DOX) resistance in a resistant breast cancer cell line.
IC50& Target:IC50: 8.92 nM (AKR1C3)
In Vitro:AKR1C3-IN-9 (compound 24) (10-100 μM; 72 h and 96 h) results weak antiproliferative effect up to 100 μM in all three breast cancer cell lines (MDA-MB-231, MCF-7). AKR1C3-IN-9 (10 μM, 25 μM, and 50 μM; 72 h) synergistically inhibits the proliferation
Biological Activity:AKR1C3-IN-9 is a selective inhibitor of Aldo-keto Reductase 1C3 (AKR1C3) with an IC 50 value of 8.92 nM. AKR1C3-IN-9 significantly reverses the Doxorubicin ( HY-15142A ) (DOX) resistance in a resistant breast cancer cell line.
Specifications
Specifications & Purity
10mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Names and Identifiers
| Molecular Weight | 352.38 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
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