Sale sodico di azlocillina - ≥99% , Penicillin-binding protein inhibitor, CAS No.37091-65-9, Penicillin-binding protein inhibitor

CAS: 37091-65-9 Cat. No.: A129398 Formula: C₂₀H₂₂N₅O₆SNa Peso molecolare: 483.47 Numero EC: 253-347-7 PubChem CID: 23685176

QUALITÀ & PUREZZA ≥99%

Synonyms

HMS2097F03 | A19406 | SW202561-3 | 4-(4-Methyl-piperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl-thiazol-2-ylamino)-phenyl]-benzamide | Securopen | sodium 2,2-dimethyl-6beta-((2R)-2-(((2-oxoimidazolidin-1-yl)carbonyl)amino)-2-phenylacetamido)penam-3alph

Storage

Conservare a 2-8°C

Shipped In

Ghiaccio umido

Panoramica

L'azlocillina è un'acilampicillina ad ampio spettro contro i batteri.
L'azlocillina è una penicillina semisintetica ed è un potente antibiotico 1-lattamico. Viene spesso utilizzata contro Pseudomonas aeruginosa ed è stata utilizzata per sviluppare nuove tecniche di quantificazione degli antibiotici

Specifiche

Sinonimi

HMS2097F03 | A19406 | SW202561-3 | 4-(4-Methyl-piperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl-thiazol-2-ylamino)-phenyl]-benzamide | Securopen | sodium 2,2-dimethyl-6beta-((2R)-2-(((2-oxoimidazolidin-1-yl)carbonyl)amino)-2-phenylacetamido)penam-3alph

Specifiche e purezza

≥99%

Meccanismi biochimici e fisiologici

L'azlocillina inibisce la sintesi della parete cellulare batterica dipendente dalla proteina legante la penicillina (PBP).

Condizioni di conservazione di stoccaggio

Conservare a 2-8°C

Spedito in

Ghiaccio umido

Tipo di azione

INHIBITOR

Meccanismo d'azione

Penicillin-binding protein inhibitor

Purezza

≥99%

Nomi e identificatori

Pubchem Sid

488200525

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488200525

Sorrisi canonici

CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)NC(=O)N4CCNC4=O)C(=O)[O-])C.[Na+]

IUPAC Name

sodium;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[(2R)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

InChIKey

UVOCNBWUHNCKJM-XFAPPKAWSA-M

INCHI

1S/C20H23N5O6S.Na/c1-20(2)13(17(28)29)25-15(27)12(16(25)32-20)22-14(26)11(10-6-4-3-5-7-10)23-19(31)24-9-8-21-18(24)30;/h3-7,11-13,16H,8-9H2,1-2H3,(H,21,30)(H,22,26)(H,23,31)(H,28,29);/q;+1/p-1/t11-,12-,13+,16-;/m1./s1

Isomeri SMILES

CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)NC(=O)N4CCNC4=O)C(=O)[O-])C.[Na+]

WGK Germania

3

RTECS

XH9250000

PubChem CID

23685176

Peso molecolare

483.47

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 N-acyl-alpha amino acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: N-acyl-alpha amino acids and derivatives
• Alternative Parents: Penams Benzene and substituted derivatives Thiazolidines Tertiary carboxylic acid amides Imidazolines Azetidines Isoureas Azacyclic compounds Thiohemiaminal derivatives Propargyl-type 1,3-dipolar organic compounds Carboximidamides Carboxylic acids Dialkylthioethers Monocarboxylic acids and derivatives Hydrocarbon derivatives Organopnictogen compounds Organic zwitterions Carbonyl compounds Organic oxides Organic sodium salts
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: N-acyl-alpha amino acid or derivatives - Penam - Monocyclic benzene moiety - Benzenoid - Beta-lactam - 2-imidazoline - Tertiary carboxylic acid amide - Thiazolidine - Carboxamide group - Azetidine - Isourea - Lactam - Azacycle - Organic alkali metal salt - Carboximidic acid - Carboximidic acid derivative - Organoheterocyclic compound - Carboxylic acid - Dialkylthioether - Organic 1,3-dipolar compound - Monocarboxylic acid or derivatives - Thioether - Hemithioaminal - Carboximidamide - Propargyl-type 1,3-dipolar organic compound - Organic oxygen compound - Organonitrogen compound - Organooxygen compound - Organopnictogen compound - Organic nitrogen compound - Organic salt - Organic sodium salt - Carbonyl group - Organic zwitterion - Organic oxide - Hydrocarbon derivative - Aromatic heteropolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as n-acyl-alpha amino acids and derivatives. These are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group at its terminal nitrogen atom.
• External Descriptors: organic sodium salt

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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ABCC3 Tbio Canalicular multispecific organic anion transporter 2 (718 Activities)

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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

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Obiettivi associati (non umani)

rep Replicase polyprotein 1ab (378 Activities)

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Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: DMSO 97 mg/mL Water 97 mg/mL Ethanol 3 mg/mL
• Peso molecolare: 483.500 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 5
• Exact Mass: 483.119 Da
• Monoisotopic Mass: 483.119 Da
• Topological Polar Surface Area: 176.000 Ų
• Heavy Atom Count: 33
• Formal Charge: 0
• Complexity: 851.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3