Beclomethasone dipropionate - Moligand™, 10mM in DMSO , Glucocorticoid receptor agonist, CAS No.5534-09-8, Glucocorticoid receptor agonist

CAS: 5534-09-8 Cat. No.: B409241 Formula: C₂₈H₃₇ClO₇ Peso molecolare: 521.04 Numero EC: 226-886-0

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

Beclometasone dipropionate | 9α-Chloro-16β-methylprednisolone 17,21-dipropionate

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Information

Beclomethasone dipropionate Beclomethasone dipropionate is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.
In vitro

Beclomethasone dipropionate (BDP) is an anti-inflammatory corticosteroid available for the treatment of asthma and allergic rhinitis (AR). BDP is previously developed as aqueous nasal formulations for the treatment of AR. BDP is also available in dry nasal aerosol formulations as chlorofluoro carbon (CFC) metered-dose inhaler nasal sprays, but CFC-containing formulations have been withdrawn from the market and currently are not available.BDP hydrofluoroalkane (HFA) inhalation aerosol currently is available for patient use and indicated for the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older.BDP HFA nasal aerosol, an intranasal aerosol formulation, has been developed recently for the treatment of AR.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Sinonimi

Beclometasone dipropionate | 9α-Chloro-16β-methylprednisolone 17,21-dipropionate

Specifiche e purezza

Moligand™, 10mM in DMSO

Meccanismi biochimici e fisiologici

Beclomethasone dipropionate is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Tipo di azione

AGONIST

Meccanismo d'azione

Glucocorticoid receptor agonist

Proprietà del prodotto

• ALogP: 3

Nomi e identificatori

• Isomeri SMILES: CCC(=O)OCC(=O)[C@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)Cl)O)C)C)OC(=O)CC
• RTECS: TU3805000
• CAS alternativo: 66734-13-2
• Peso molecolare: 521.04
• Reaxy-Rn: 24731460
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24731460&ln=

Obiettivi associati (umani)

ADGRG3 Tchem Adhesion G protein-coupled receptor G3 (1 Activities)

Discover Target: ADGRG3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Proprietà chimiche e fisiche

• Punto di fusione (°C): 208-210°C

Riferimenti

1. Youfang Huang, Yanyun Li, Qing Luo, Xiaojia Huang.  (2020)  One-step preparation of functional groups-rich graphene oxide and carbon nanotubes nanocomposite for efficient magnetic solid phase extraction of glucocorticoids in environmental waters.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2020.126785]