≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Panoramica
BI-4924 is a lipophilic, highly plasma protein bound selective phosphoglycerate dehydrogenase ( PHGDH ) inhibitor ( IC 50 =3 nM) with excellent microsomal, as well as hepatocytic stability. Intracellular trapping of BI-4924 disrupts serine biosynthesis with an IC 50 of 2200 nM at 72 h
In Vitro
BI-4924 is a highly potent co-factor nicotinamide adenine dinucleotide (NADH/NAD + )-competitive PHGDH inhibitor. BI-4924 shows high selectivity against the majority of other dehydrogenase targets. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:PHGDH
Specifications
Specifiche e purezza
≥99%
Meccanismi biochimici e fisiologici
BI-4924 is a lipophilic, highly plasma protein bound selective phosphoglycerate dehydrogenase ( PHGDH ) inhibitor ( IC 50 =3 nM) with excellent microsomal, as well as hepatocytic stability. Intracellular trapping of BI-4924 disrupts serine biosynthesis wi
Condizioni di conservazione di stoccaggio
Store at -20°C
Spedito in
Ice chest + Ice pads
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