(±)-BI-D - 10mM in DMSO , CAS No.1416258-16-6

CAS: 1416258-16-6 Cat. No.: B656858 Molecular Weight: 405.49

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

(±)-BI-D is a potent ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site.IC50 value: 2.4–2.9 μM(HIV-Luc infection of WT and Hdgfrp2 KO cells) Target: integrase inhibitorin vitro: Approximately 2.4–2.9 μM of BI-D was required to inhibit 50% of HIV-Luc infection of WT and Hdgfrp2 KO cells, while the IC50 decreased dramatically, to 160–200 nM, in Psip1 and double-KO cells.

Specifications

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

(±)-BI-D is a potent ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site.\nIC50 value: 2.4–2.9 μM(HIV-Luc infection of WT and Hdgfrp2 KO cells) \nTarget: integrase inhibitor\nin vitro: Approximately 2.4–2.9 μM of BI-D

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Names and Identifiers

• Molecular Weight: 405.49