Biotin-PEG2-azide - ≥98% , CAS No.1910803-72-3

CAS: 1910803-72-3 Cat. No.: B595446 Formula: C₁₆H₂₈N₆O₄S Peso molecolare: 400.5

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Biotin-PEG2-azide is PEG derivative containing a biotin group and an azide group. The azide group can react with either alkyne moiety in Cu(I)-catalyzed Click Chemistry reaction or DBCO moiety in copper-free Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.

Specifications

Specifiche e purezza

≥98%

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥98%

Nomi e identificatori

• Sorrisi canonici: C1C2C(C(S1)CCCCC(=O)NCCOCCOCCN=[N+]=[N-])NC(=O)N2
• IUPAC Name: N-[2-[2-(2-azidoethoxy)ethoxy]ethyl]-5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide
• InChIKey: OVEZMVONEJMGLZ-UHFFFAOYSA-N
• INCHI: 1S/C16H28N6O4S/c17-22-19-6-8-26-10-9-25-7-5-18-14(23)4-2-1-3-13-15-12(11-27-13)20-16(24)21-15/h12-13,15H,1-11H2,(H,18,23)(H2,20,21,24)
• Peso molecolare: 400.5
• Reaxy-Rn: 50740936
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=50740936&ln=

Proprietà chimiche e fisiche

• Solubilità: Solubility in Water, DMSO, DCM, DMF

Riferimenti

1. Jia Mutian, Wang Yuanyuan, Wang Jie, Qin Danhui, Wang Mengge, Chai Li, Fu Yue, Zhao Chunyuan, Gao Chengjiang, Jia Jihui, Zhao Wei.  (2023)  Myristic acid as a checkpoint to regulate STING-dependent autophagy and interferon responses by promoting N-myristoylation.  Nature Communications,  14  (1): (1-12).  [PMID:36750575] [10.1038/s41467-023-36332-3]