Bis-PEG5-NHS ester - ≥98% , CAS No.756526-03-1
Disponibile
SKU
B595340
Bis-PEG-NHS
Bis-PEG5-NHS ester is a PEG derivative containing two NHS ester groups. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Features and Benefits
· Reactive groups: NHS ester (both ends)
· Reactive towards: amino groups (primary amines)
· NHS esters react with—NH2 groups at pH 7-9, forming stable amide bonds
· Water-soluble; compare to non-pegylated BS3 (also soluble) and DSS (water-insoluble)
· Membrane-impermeable, allowing for cell surface labeling
· Irreversibly crosslink proteins or peptides by flexible PEG spacer arms
· Polyethylene glycol spacer arms help maintain conjugate solubility
· Pure compound with defined structure and molecular weight, ensuring reproducible protein-modification effects
· PEG spacer provides unique advantages, including increased stability, reduced tendency toward aggregation and reduced immunogenicity
· Ideal for small molecule or peptide conjugations
Maggiori Informazioni
| CAS | 756526-03-1 |
|---|---|
| Sinonimi | Bis-dPEG(R)5-NHS ester | PEG5 BIS-NHS ESTER | AKOS027250858 | GS-6157 | BP-20429 | (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate | bis(2,5-dioxopyrrolidin-1-yl) 4,7,10,13,16-p |
| Specifiche e purezza | ≥98% |
| Condizioni di conservazione di stoccaggio | Store at -20°C,Argon charged |
| Spedito in | Ice chest + Ice pads |
| Product Description | Bis-PEG5-NHS ester is a PEG derivative containing two NHS ester groups. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Features and Benefits |
| Pubchem Sid | 528770475 |
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/528770475 |
| Solubilità | Solubility in DMSO, DCM, DMF |
| Sensibilità | Heat and moisture sensitive |
| Numero CE | 887-362-0 |
| PubChem CID | 51340935 |
| Formula molecolare | C22H32N2O13 |
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