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· · COA & SDS available for every product · Same-day shipping on in-stock items BLZ945 - Moligand™, ≥98% , Inhibitor of colony stimulating factor 1 receptor;Inhibitor of KIT proto-oncogene; receptor tyrosine kinase;Inhibitor of platelet derived growth factor receptor beta, CAS No.953769-46-5, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of KIT proto-oncogene; receptor tyrosine kinase;Inhibitor of platelet derived growth factor receptor beta
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Synonyms
AC-32994 | BLZ 945 [WHO-DD] | EX-A817 | HB4634 | NCGC00386432-03 | BB178452 | AB00534 | CCG-268639 | GTPL8250 | ADZBMFGQQWPHMJ-RHSMWYFYSA-N | STL564798 | Pyridoxamine dihydrochloride, Cell Culture Reagent | 4-((2-(((1R,2R)-2-Hydroxycyclohexyl)amino)benzo-
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview BLZ945 is a tumor-associated macrophage targeting the treatment of glioblastoma multiforme, a most common type of aggresive brain cancer.
Specifications Synonyms
AC-32994 | BLZ 945 [WHO-DD] | EX-A817 | HB4634 | NCGC00386432-03 | BB178452 | AB00534 | CCG-268639 | GTPL8250 | ADZBMFGQQWPHMJ-RHSMWYFYSA-N | STL564798 | Pyridoxamine dihydrochloride, Cell Culture Reagent | 4-((2-(((1R, 2R)-2-Hydroxycyclohexyl)amino)benzo-
Specifications & Purity
Moligand™, ≥98%
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Inhibitor of colony stimulating factor 1 receptor;Inhibitor of KIT proto-oncogene; receptor tyrosine kinase;Inhibitor of platelet derived growth factor receptor beta
Names and Identifiers Pubchem Sid 504770670 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504770670 Canonical Smiles CNC(=O)C1=NC=CC(=C1)OC2=CC3=C(C=C2)N=C(S3)NC4CCCCC4O IUPAC Name 4-[[2-[[(1R,2R)-2-hydroxycyclohexyl]amino]-1,3-benzothiazol-6-yl]oxy]-N-methylpyridine-2-carboxamide InChIKey ADZBMFGQQWPHMJ-RHSMWYFYSA-N INCHI 1S/C20H22N4O3S/c1-21-19(26)16-10-13(8-9-22-16)27-12-6-7-15-18(11-12)28-20(24-15)23-14-4-2-3-5-17(14)25/h6-11,14,17,25H,2-5H2,1H3,(H,21,26)(H,23,24)/t14-,17-/m1/s1 Isomeric SMILES CNC(=O)C1=NC=CC(=C1)OC2=CC3=C(C=C2)N=C(S3)N[C@@H]4CCCC[C@H]4O Molecular Weight 398.48 Reaxy-Rn 26002377 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=26002377&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organic oxygen compounds Class Organooxygen compounds Subclass Ethers Intermediate Tree Nodes Not available Direct Parent Diarylethers Alternative Parents Pyridinecarboxamides Benzothiazoles 2-heteroaryl carboxamides Secondary alkylarylamines Cyclohexanols Benzenoids 2-amino-1,3-thiazoles Heteroaromatic compounds Secondary carboxylic acid amides Cyclic alcohols and derivatives Amino acids and derivatives Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents Diaryl ether - Pyridine carboxylic acid or derivatives - Pyridinecarboxamide - 1,3-benzothiazole - 2-heteroaryl carboxamide - Secondary aliphatic/aromatic amine - Cyclohexanol - 1,3-thiazol-2-amine - Benzenoid - Pyridine - Heteroaromatic compound - Thiazole - Cyclic alcohol - Azole - Secondary carboxylic acid amide - Secondary alcohol - Carboxamide group - Amino acid or derivatives - Azacycle - Organoheterocyclic compound - Secondary amine - Carboxylic acid derivative - Organic nitrogen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organonitrogen compound - Amine - Alcohol - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as diarylethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are aryl groups. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Molecular Weight 398.500 g/mol XLogP3 3.400 Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 7 Rotatable Bond Count 5 Exact Mass 398.141 Da Monoisotopic Mass 398.141 Da Topological Polar Surface Area 125.000 Ų Heavy Atom Count 28 Formal Charge 0 Complexity 540.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 2 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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