BMS-1001 hydrochloride - 10mM in DMSO , CAS No.2113650-04-5

CAS: 2113650-04-5 Cat. No.: B656675 Formula: C₃₅H₃₅ClN₂O₇ Peso molecolare: 631.12

GRADE & PURITY 10mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

BMS-1001 hydrochloride is an orally active human PD-L1/PD-1 immune checkpoint inhibitor. BMS-1001 hydrochloride exhibits low-toxicity in cells

In Vitro

BMS-1001 binds to human PD-L1 and blocks its interaction with PD-1. BMS-1001 presents low toxicity towards tested cell lines and block the interaction of soluble PD-L1 with the cell surface-expressed PD-1. BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:PD-L1/PD-1

Specifications

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

BMS-1001 hydrochloride is an orally active human PD-L1/PD-1 immune checkpoint inhibitor. BMS-1001 hydrochloride exhibits low-toxicity in cells.

Condizioni di conservazione di stoccaggio

Desiccated,Store at -80°C

Spedito in

Dry ice packs + Cold packs

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Tipo di azione

INHIBITOR

Nomi e identificatori

CAS alternativo

2113650-03-4

Peso molecolare

631.12