Determine the necessary mass, volume, or concentration for preparing a solution.
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Description
This is a crosslinker with a bromo group on one end and a carboxyl group on the other end. The compound contains three PEG units to help improve solubility.Bromo-PEG3-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG3-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC®molecules) fortargeted protein degradation.
| Pubchem Sid | 508814517 |
|---|---|
| Sorrisi canonici | C(COCCOCCOCCBr)C(=O)O |
| IUPAC Name | 3-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]propanoic acid |
| InChIKey | OKWHCSUISPMYIJ-UHFFFAOYSA-N |
| INCHI | 1S/C9H17BrO5/c10-2-4-14-6-8-15-7-5-13-3-1-9(11)12/h1-8H2,(H,11,12) |
| Isomeri SMILES | C(COCCOCCOCCBr)C(=O)O |
| Peso molecolare | 285.13 |
| Reaxy-Rn | 32168850 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=32168850&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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| Lot Number | Certificate Type | Data | Oggetto |
|---|---|---|---|
| Certificate of Analysis | Aug 24, 2023 | B487282 | |
| Certificate of Analysis | Aug 24, 2023 | B487282 | |
| Certificate of Analysis | Aug 24, 2023 | B487282 | |
| Certificate of Analysis | Aug 24, 2023 | B487282 |
| Sensibilità | Moisture sensitive |
|---|---|
| Peso molecolare | 285.130 g/mol |
| XLogP3 | 0.000 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 11 |
| Exact Mass | 284.026 Da |
| Monoisotopic Mass | 284.026 Da |
| Topological Polar Surface Area | 65.000 Ų |
| Heavy Atom Count | 15 |
| Formal Charge | 0 |
| Complexity | 153.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |