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BioReagent BioReagent for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Calcium (calcium) is typically the most abundant mineral in the bodies of mammals and is involved in regulating numerous cellular life processes. It is also one of the most important intracellular regulatory factors. Calcium can exist in two forms: as free ions or as complexes with bound calcium ions, such as calcium phosphate and calcium carbonate, which are components of bone tissue. A wide range of physiological processes, including muscle contraction, cell adhesion, hormone/neurotransmitter release, glycogen metabolism, cell proliferation/differentiation, blood coagulation, neural or synaptic transmission, and bone structure support, are regulated by calcium signaling. Defects in the integrity of cell-specific calcium signaling systems can lead to the development of various diseases. Although 99% of the calcium in the human body is found in bones and teeth, clinical attention is often focuse on blood calcium levels, known as serum calcium. Blood calcium levels are primarily regulated by parathyroid hormone, which controls the storage or release of calcium from bones to prevent hypercalcemia or hypocalcemia. Calcium in serum exists primarily in three forms: approximately 50% as free calcium ions, about 45% as protein-bound calcium, and about 5% as calcium complexes (mainly calcium citrate). Calcium levels are typically inversely related to phosphorus levels. Calcium Content Assay Kit (o-Cresolphthalein Complexone, Micro Method) provides a simple, convenient, and rapid method for detecting calcium ion content, suitable for animal and plant tissues, cells, serum (plasma) or other Liquid samples. The principle is based on the reaction of calcium ions with o-cresolphthalein complexone under alkaline conditions to form a purple complex. The calcium ion content can be quantitatively determined by measuring the absorbance at 575 nm.
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