Caracemide - 10mM in DMSO , CAS No.81424-67-1

CAS: 81424-67-1 Cat. No.: C654538 Formula: C₆H₁₁N₃O₄ Peso molecolare: 189.17 PubChem CID: 54747

QUALITÀ & PUREZZA 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide is a novel anticancer agent derived from a hydroxamic acid and has demonstrated to produce severe central nervous system (CNS) toxicity.

In Vitro

Caracemide inactivates R1 by covalent modification at the substrate-binding site and has a toxic metabolite, methylisocyanate (MIC), in vivo . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

The mercapturic acid derivative AMCC was identified in urine rats following administration to rats of a single i.p. dose (6.6 mg/kg) of caracemide (NSC-253272) . . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Specifiche

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide is a novel anticancer agent derived from a hydroxamic acid and has demonstrated to produce severe central nervous system (CNS) toxicity.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

INHIBITOR

Nomi e identificatori

Isomeri SMILES

CC(=O)N(C(=O)NC)OC(=O)NC

PubChem CID

54747

Peso molecolare

189.17