Trova piccole molecole associate alla via di segnalazione TGF-beta/Smad per la ricerca sulla fibrosi, gli studi sulla differenziazione e l'analisi delle interazioni tra vie di segnalazione. Utilizza questa pagina per esplorare i composti rilevanti per il controllo della crescita, la segnalazione dello sviluppo e la biologia traslazionale.
TGF-beta/Smad
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- Bisindolylmaleimide X hydrochloride (Ro 31-8425)CAS: 145317-11-9 Formula: C26H25ClN4O2 Peso molecolare: 460.96◐ .Su ordinazione · 8–12 settimane Oggetto #: B275168Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 3-[8-(aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dione;hydrochloride
- SMILES
- CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C5CC(CCN5C6=CC=CC=C64)CN.Cl
- InChIKey
- IMBOYWXMTUUYGZ-UHFFFAOYSA-N
- InChI
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- Sinonimi
- 3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dionehydrochloride
- GSK 269962, Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of Rho associated coiled-coil containing protein kinase 2CAS: 850664-21-0 Formula: C29H30N8O5 Peso molecolare: 570.6Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: G287476Visualizza prodottoPrezzi e dimensioni del pacchetto
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- Nome IUPAC
- N-[3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-6-yl]oxyphenyl]-4-(2-morpholin-4-ylethoxy)benzamide
- SMILES
- CCN1C2=CC(=NC=C2N=C1C3=NON=C3N)OC4=CC=CC(=C4)NC(=O)C5=CC=C(C=C5)OCCN6CCOCC6
- InChIKey
- YOVNFNXUCOWYSG-UHFFFAOYSA-N
- InChI
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- GTPL8037 | NSC-767348 | SCHEMBL1838346 | UNII-F89KMM7TE2 | N-(3-((2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo...
- Bisindolylmaleimide IIICAS: 137592-43-9 Formula: C23H20N4O2 Peso molecolare: 384.43● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: B276080Visualizza prodottoPrezzi e dimensioni del pacchetto
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- Nome IUPAC
- 3-[1-(3-aminopropyl)indol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione
- SMILES
- C1=CC=C2C(=C1)C(=CN2)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)CCCN
- InChIKey
- APYXQTXFRIDSGE-UHFFFAOYSA-N
- InChI
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- 3-[1-(3-Aminopropyl)indol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione
- N-octanoyl-D-erythro-sphingosineCAS: 74713-59-0 Formula: C26H51NO3 Peso molecolare: 425.688● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: N130616Visualizza prodottoPrezzi e dimensioni del pacchetto
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- Nome IUPAC
- N-[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]octanamide
- SMILES
- CCCCCCCCCCCCCC=CC(C(CO)NC(=O)CCCCCCC)O
- InChIKey
- APDLCSPGWPLYEQ-WRBRXSDHSA-N
- InChI
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- BSPBio_001569 | HMS1361O11 | N-octanoylsphing-4-enine | SCHEMBL14020687 | DTXSID701318293 | SR-01000946565 | N-Octano...
- N-octanoyl-D-erythro-sphinganineCAS: 145774-33-0 Formula: C26H53NO3 Peso molecolare: 427.7◐ .Su ordinazione · 8–12 settimane Oggetto #: N130688Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]octanamide
- SMILES
- CCCCCCCCCCCCCCCC(C(CO)NC(=O)CCCCCCC)O
- InChIKey
- LGOFBZUQIUVJFS-LOSJGSFVSA-N
- InChI
- 1S/C26H53NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h24-25,28-29H,3-23H2,1-2H3,(H,27,30)/t24-,25+/m0/s1
- Sinonimi
- EC 214-269-9 | N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]octanamide | C8 Dihydroceramide [N-Octanoylsphinganine] | KBioS...
- Bisindolylmaleimide IICAS: 137592-45-1 Formula: C27H26N4O2 Peso molecolare: 438.52◐ .Su ordinazione · 8–12 settimane Oggetto #: B276515Visualizza prodottoPrezzi e dimensioni del pacchetto
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- Nome IUPAC
- 3-(1H-indol-3-yl)-4-[1-[2-(1-methylpyrrolidin-2-yl)ethyl]indol-3-yl]pyrrole-2,5-dione
- SMILES
- CN1CCCC1CCN2C=C(C3=CC=CC=C32)C4=C(C(=O)NC4=O)C5=CNC6=CC=CC=C65
- InChIKey
- LBFDERUQORUFIN-UHFFFAOYSA-N
- InChI
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- Bisindolyl deriv. 22 | 2-[1-[2-(1-Methylpyrrolidino)ethyl]-1H-indol-3-yl]-3-(1H-indol-3-yl)maleimide | SCHEMBL7978085...
- Bisindolylmaleimide IV, Inhibitor of protein kinase C betaCAS: 119139-23-0 Formula: C20H13N3O2 Peso molecolare: 327.34Solido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(TLC)● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: B166335Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 3,4-bis(1H-indol-3-yl)pyrrole-2,5-dione
- SMILES
- C1=CC=C2C(=C1)C(=CN2)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54
- InChIKey
- DQYBRTASHMYDJG-UHFFFAOYSA-N
- InChI
- 1S/C20H13N3O2/c24-19-17(13-9-21-15-7-3-1-5-11(13)15)18(20(25)23-19)14-10-22-16-8-4-2-6-12(14)16/h1-10,21-22H,(H,23,24,25)
- Sinonimi
- CCG-206739 | HMS3229C03 | RO-316233 | Ro-31-6233 | DTXSID30152324 | FT-0694431 | GTPL5937 | HMS3401J13 | MBK3OO5K8T |...
- N⁶,2′-O-Dibutyryladenosine 3′,5′ -cyclic monophosphate sodium saltSolido ≥97%(HPLC)● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: D124575Visualizza prodottoPrezzi e dimensioni del pacchetto
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- Nome IUPAC
- sodium;[(4aR,6R,7R,7aR)-6-[6-(butanoylamino)purin-9-yl]-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl] butanoate
- SMILES
- CCCC(=O)NC1=C2C(=NC=N1)N(C=N2)C3C(C4C(O3)COP(=O)(O4)[O-])OC(=O)CCC.[Na+]
- InChIKey
- KRBZRVBLIUDQNG-JBVYASIDSA-M
- InChI
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- Dibutyryl cAMP (sodium salt);DBcAMP (sodium salt) | InChI=1/C6H10O2/c7-6-4-2-1-3-5-8-6/h1-5H | Actosin | Adenosine, N...
- LY2157299, TGF-beta receptor type I inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: L126937Visualizza prodottoPrezzi e dimensioni del pacchetto
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- Nome IUPAC
- 4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide
- SMILES
- CC1=NC(=CC=C1)C2=NN3CCCC3=C2C4=C5C=C(C=CC5=NC=C4)C(=O)N
- InChIKey
- IVRXNBXKWIJUQB-UHFFFAOYSA-N
- InChI
- 1S/C22H19N5O/c1-13-4-2-5-18(25-13)21-20(19-6-3-11-27(19)26-21)15-9-10-24-17-8-7-14(22(23)28)12-16(15)17/h2,4-5,7-10,12H,3,6,11H2,1H3,(H2,23,28)
- Sinonimi
- BDBM50015640 | 4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl]quinoline-6-carboxamide | MFCD00...
- Bisindolylmaleimide VIII acetateCAS: 138516-31-1 Formula: C24H22N4O2.CH3CO2H Peso molecolare: 458.51● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: B274850Visualizza prodottoPrezzi e dimensioni del pacchetto
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- Nome IUPAC
- acetic acid;3-[1-(3-aminopropyl)indol-3-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dione
- SMILES
- CC(=O)O.CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)CCCN
- InChIKey
- VEOXVBTXROWDAH-UHFFFAOYSA-N
- InChI
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- Sinonimi
- HMS3648M22 | Z2037279705 | Bis VIII acetate | Bis VIII acetateRo 31-7549 acetate | DTXSID50432099 | 1-(p-Fluorophenyl...
- LY2109761, Inhibitor of transforming growth factor beta receptor 1;Inhibitor of transforming growth factor beta receptor 2CAS: 700874-71-1 Formula: C26H27N5O2 Peso molecolare: 441.52Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: L126135Visualizza prodottoPrezzi e dimensioni del pacchetto
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- Nome IUPAC
- 4-[2-[4-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl]oxyethyl]morpholine
- SMILES
- C1CC2=C(C(=NN2C1)C3=CC=CC=N3)C4=C5C=CC(=CC5=NC=C4)OCCN6CCOCC6
- InChIKey
- IHLVSLOZUHKNMQ-UHFFFAOYSA-N
- InChI
- 1S/C26H27N5O2/c1-2-9-27-22(4-1)26-25(24-5-3-11-31(24)29-26)21-8-10-28-23-18-19(6-7-20(21)23)33-17-14-30-12-15-32-16-13-30/h1-2,4,6-10,18H,3,5,11-17H2
- Sinonimi
- HMS3674E17 | SB19481 | AKOS022183732 | GTPL8075 | BCP9000868 | LY 2109761 | Q27082613 | .ALPHA.-KETOGLUCONIC ACID | Q...
- LY-333531 hydrochlorideCAS: 169939-93-9 Formula: C28H28N4O3 · HCl Peso molecolare: 505.01● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: L274839Visualizza prodottoPrezzi e dimensioni del pacchetto
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- Nome IUPAC
- show more
- SMILES
- CN(C)CC1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O.Cl
- InChIKey
- NYQIEYDJYFVLPO-FERBBOLQSA-N
- InChI
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- Sinonimi
- LY333531 HCl | (9S)-9-[(DiMethylaMino)Methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-DiMethenodibenzo[e,k]pyrrolo[3,4...
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Domande frequenti
What should I consider when selecting a TGF-beta/Smad product?
Define the transformation first, then narrow the TGF-beta/Smad listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which TGF-beta/Smad subcategory should I start with?
TGF-beta/Smad is organised into PKA, PKC, ROCK, TGF-beta/Smad and TGF-β Receptor. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering TGF-beta/Smad?
Review the lot-specific Certificate of Analysis for the TGF-beta/Smad product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search TGF-beta/Smad by structure or CAS number?
Yes. Within TGF-beta/Smad you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].