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· · COA & SDS Disponibile per ogni prodotto · Spedizione lo stesso giorno su articoli in magazzino CB-839 - Moligand™, ≥98% , Glutaminase kidney isoform, mitochondrial inhibitor, CAS No.1439399-58-2, Glutaminase kidney isoform, mitochondrial inhibitor
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Synonyms
A14396 | U6CL98GLP4 | A857288 | EX-A1310 | MFCD28167826 | AS-75090 | HMS3873G13 | NCGC00356145-11 | WHO 10815 | CB839; CB 839 pound>>Telaglenastat,
Storage
Protected from light,Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Protected from light,Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 4 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Panoramica Biochemical mechanism:
Cell permeable: yes
Primary Target
GLS1
Reversible: yes
Target IC50: 23 nM & 28 nM, respectively, using murine kidney and brain homogenates
Specifications Sinonimi
A14396 | U6CL98GLP4 | A857288 | EX-A1310 | MFCD28167826 | AS-75090 | HMS3873G13 | NCGC00356145-11 | WHO 10815 | CB839; CB 839 pound>>Telaglenastat,
Specifiche e purezza
Moligand™, ≥98%
Condizioni di conservazione di stoccaggio
Protected from light,Store at -20°C,Argon charged
Spedito in
Ice chest + Ice pads
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Meccanismo d'azione
Glutaminase kidney isoform, mitochondrial inhibitor
Proprietà del prodotto Nomi e identificatori Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/488202265
Sorrisi canonici
C1=CC=NC(=C1)CC(=O)NC2=NN=C(S2)CCCCC3=NN=C(C=C3)NC(=O)CC4=CC(=CC=C4)OC(F)(F)F
IUPAC Name
N-[6-[4-[5-[(2-pyridin-2-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]-2-[3-(trifluoromethoxy)phenyl]acetamide
InChIKey
PRAAPINBUWJLGA-UHFFFAOYSA-N
INCHI
1S/C26H24F3N7O3S/c27-26(28,29)39-20-9-5-6-17(14-20)15-22(37)31-21-12-11-18(33-34-21)7-1-2-10-24-35-36-25(40-24)32-23(38)16-19-8-3-4-13-30-19/h3-6,8-9,11-14H,1-2,7,10,15-16H2,(H,31,34,37)(H,32,36,38)
Isomeri SMILES
C1=CC=NC(=C1)CC(=O)NC2=NN=C(S2)CCCCC3=NN=C(C=C3)NC(=O)CC4=CC(=CC=C4)OC(F)(F)F
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=23710292&ln=
Documentazione 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Classe Benzene and substituted derivatives Subclass Phenylacetamides Intermediate Tree Nodes Not available Direct Parent Phenylacetamides Alternative Parents Phenoxy compounds Phenol ethers N-arylamides Pyridines and derivatives Pyridazines and derivatives Imidolactams Thiadiazoles Heteroaromatic compounds Trihalomethanes Secondary carboxylic acid amides Azacyclic compounds Hydrocarbon derivatives Organic oxides Carbonyl compounds Organofluorides Alkyl fluorides Molecular Framework Aromatic heteromonocyclic compounds Substituents Phenylacetamide - Phenoxy compound - Phenol ether - N-arylamide - Pyridazine - Pyridine - Imidolactam - Azole - Thiadiazole - Heteroaromatic compound - Carboxamide group - Trihalomethane - Secondary carboxylic acid amide - Carboxylic acid derivative - Azacycle - Organoheterocyclic compound - Halomethane - Alkyl halide - Organic oxide - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Alkyl fluoride - Carbonyl group - Organic nitrogen compound - Hydrocarbon derivative - Aromatic heteromonocyclic compound Descrizione This compound belongs to the class of organic compounds known as phenylacetamides. These are amide derivatives of phenylacetic acids. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Struttura 3D Obiettivi associati (umani) Obiettivi associati (non umani) Meccanismi d'azione Certificati (CoA, COO, BSE/TSE e tabella di analisi) Proprietà chimiche e fisiche Solubilità Chloroform (Slightly, Sonicated), DMSO (Slightly, Sonicated), Methanol (Slightly Sensibilità light sensitive Punto di fusione (°C) 186- 189° C Peso molecolare 571.600 g/mol XLogP3 3.600 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 12 Rotatable Bond Count 12 Exact Mass 571.161 Da Monoisotopic Mass 571.161 Da Topological Polar Surface Area 160.000 Ų Heavy Atom Count 40 Formal Charge 0 Complexity 812.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
Domande frequenti e articoli Citations of This Product Calcolatori di soluzioni Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator Recensioni Need help choosing the grade? Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →
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