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CC-99677 - ≥98% , CAS No.1887069-10-4
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
CC-99677 is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 ( MK2 ) pathway in both biochemical ( IC 50 =156.3 nM) and cell based assays ( EC 50 =89 nM). CC-99677 is extracted from patent WO2020236636, compound 1
In Vitro
CC-99677 is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 ( MK2 ) pathway in both biochemical ( IC 50 =156.3 nM) and cell based assays ( EC 50 =89 nM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:MK2
Specifications
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
CC-99677 is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 ( MK2 ) pathway in both biochemical ( IC 50 =156.3 nM) and cell based assays ( EC 50 =89 nM). CC-99677 is extracted from pa
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Purity
≥98%
Names and Identifiers
| Isomeric SMILES | CCOCC1=CN=C(N=C1OC2=NC3=C(C=C2)C4=C(C=C3)SC5=C4NC[C@H](NC5=O)C)Cl |
|---|---|
| PubChem CID | 118936948 |
| Molecular Weight | 469.94 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Solubility | DMSO : 37.5 mg/mL (79.80 mM; ultrasonic and warming and heat to 60°C) |
|---|---|
| Molecular Weight | 469.900 g/mol |
| XLogP3 | 4.500 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 5 |
| Exact Mass | 469.098 Da |
| Monoisotopic Mass | 469.098 Da |
| Topological Polar Surface Area | 127.000 Ų |
| Heavy Atom Count | 32 |
| Formal Charge | 0 |
| Complexity | 677.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
Solution Calculators
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