CCR1 antagonist 9 - 10mM in DMSO , CAS No.1220026-26-5

CAS: 1220026-26-5 Cat. No.: C656226 Formula: C₂₀H₁₆FN₅O₃S Peso molecolare: 425.44 PubChem CID: 59278314

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

CCR1 antagonist 9 is a potent and selective CCR1 antagonist with an IC 50 of 6.8 nM in calcium flux assay

In Vitro

CCR1 antagonist 9 (Compound 19e) blocks the CCR1 chemotaxis of THP-1 cells with an IC 50 of 28 nM. CCR1 antagonist 9 also blocks hERG with an IC 50 of 30 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:CCR1 6.8 nM (IC 50 , in calcium flux assay)

Specifications

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

CCR1 antagonist 9 is a potent and selective CCR1 antagonist with an IC 50 ofu202f6.8 nM in calcium flux assay.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

ANTAGONIST

Nomi e identificatori

• Isomeri SMILES: CS(=O)(=O)C1=NC=CC(=C1)CNC(=O)C2=CN=CC3=C2C=NN3C4=CC=C(C=C4)F
• PubChem CID: 59278314
• Peso molecolare: 425.44

Obiettivi associati (umani)

CCR1 Tchem C-C chemokine receptor type 1 (3 Activities)

Discover Target: CCR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)