Cervonic Acid（DHA） - Moligand™, ≥98% , Agonist of FFA1 receptor;Activator of K 2P10.1;Agonist of Retinoid X receptor-α;Activator of TRPA1, CAS No.6217-54-5, Agonist of FFA1 receptor;Activator of K 2P10.1;Agonist of Retinoid X receptor-α;Activator of TRPA1

Name: Cervonic Acid（DHA） - Moligand™, ≥98% , Agonist of FFA1 receptor;Activator of K 2P10.1;Agonist of Retinoid X receptor-α;Activator of TRPA1, CAS No.6217-54-5, Agonist of FFA1 receptor;Activator of K 2P10.1;Agonist of Retinoid X receptor-α;Activator of TRPA1
SKU: D100925
Availability: InStock

CAS: 6217-54-5 Cat. No.: D100925 Formula: C₂₂H₃₂O₂ Peso molecolare: 328.49 Numero EC: 612-950-9

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Cervonic Acid（DHA） - Moligand™, ≥98% CAS No(6217-54-5) D100925 by Aladdin Scientific

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Disponibile su ordine

GRADE & PURITY Moligand™ ? ≥98%

Synonyms

DHA | AB01563379_01 | 4,7,10,13,16,19-Docosahexaenoate | 4-cis,7-cis,10-cis,13-cis,16-cis,19-cis-Docosahexaenoic acid | LMFA01030185 | MLS004773950 | N-(2-(1H-Imidazol-5-yl)ethyl)-3-aminopropanamidedihydrochloride | NCGC00161345-05 | BP-29833 | HY-B2167 |

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Application

Drug Delivery, Surface Modification, PEGylation of Protein, Peptide & Oligo

Panoramica Specifications Nomi e identificatori Documentazione Advanced Data Taxonomic Classification Struttura 3D Obiettivi associati (umani) Obiettivi associati (non umani) Meccanismi d'azione Certificati (CoA, COO, BSE/TSE e tabella di analisi) Proprietà chimiche e fisiche Domande frequenti e articoli Citations of This Product Calcolatori di soluzioni Recensioni

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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Panoramica

DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total PUFA pool in retinal and neuronal membranes. Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa. Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.
Docosahexaenoic acid, DHA, is an omega-3 polyunsaturated fatty acid with 22 carbons and six double bonds, the first double bond occuring at position three from the methyl terminus (22:6 n-3). DHA is a component of lipid membranes and the myelin sheath. DHA also serves as a precursor for signaling molecules such as prostaglandins and eicosanoids.

Specifications

Sinonimi

Specifiche e purezza

Moligand™, ≥98%

Meccanismi biochimici e fisiologici

Endogenous omega-3 fatty acid. Acts as a selective retinoid X receptor (RXR) agonist that displays no activity at RAR, thyroid hormone receptor or the vitamin D receptor (VDR). Activates all three RXR isoforms. Also shown to inhibit Aβ1-42 fibrillation an

Condizioni di conservazione di stoccaggio

Store at -20°C,Argon charged

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Tipo di azione

ACTIVATOR, AGONIST

Meccanismo d'azione

Agonist of FFA1 receptor;Activator of K 2P10.1;Agonist of Retinoid X receptor-α;Activator of TRPA1

Purezza

≥98%

Nomi e identificatori

Pubchem Sid

508817103

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/508817103

Sorrisi canonici

CCC=CCC=CCC=CCC=CCC=CCC=CCCC(=O)O

IUPAC Name

(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid

InChIKey

MBMBGCFOFBJSGT-KUBAVDMBSA-N

INCHI

1S/C22H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h3-4,6-7,9-10,12-13,15-16,18-19H,2,5,8,11,14,17,20-21H2,1H3,(H,23,24)/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18-

Isomeri SMILES

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)O

WGK Germania

Peso molecolare

328.49

Reaxy-Rn

8214614

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8214614&ln=

Documentazione

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
  - Classe Fatty Acyls
    - Subclass Fatty acids and conjugates

Kingdom	Organic compounds
Superclass	Lipids and lipid-like molecules
Classe	Fatty Acyls
Subclass	Fatty acids and conjugates
Intermediate Tree Nodes	Not available
Direct Parent	Very long-chain fatty acids
Alternative Parents	Unsaturated fatty acids Straight chain fatty acids Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic acyclic compounds
Substituents	Very long-chain fatty acid - Unsaturated fatty acid - Straight chain fatty acid - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic acyclic compound
Descrizione	This compound belongs to the class of organic compounds known as very long-chain fatty acids. These are fatty acids with an aliphatic tail that contains at least 22 carbon atoms.
External Descriptors	Unsaturated fatty acids
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Struttura 3D

Obiettivi associati (umani)

FFAR1 Tchem Free fatty acid receptor 1 (0 Activities)

Discover Target: FFAR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RXRA Tclin Retinoic acid receptor RXR-alpha (0 Activities)

Discover Target: RXRA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TRPA1 Tclin Transient receptor potential cation channel subfamily A member 1 (1 Activities)

Discover Target: TRPA1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNK10 Tclin Potassium channel subfamily K member 10 (0 Activities)

Discover Target: KCNK10

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

VDR Tclin Vitamin D receptor (26531 Activities)

Discover Target: VDR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP19A1 Tclin Cytochrome P450 19A1 (6099 Activities)

Discover Target: CYP19A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)

Discover Target: PTGS1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)

Discover Target: PTGS2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)

Discover Target: PPARG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RXRA Tclin Retinoid X receptor alpha (3637 Activities)

Discover Target: RXRA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CFTR Tclin Cystic fibrosis transmembrane conductance regulator (2075 Activities)

Discover Target: CFTR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RBP4 Tchem Plasma retinol-binding protein (718 Activities)

Discover Target: RBP4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

143B (353 Activities)

Lot Number	Certificate Type	Data	Oggetto
J2610377	Certificate of Analysis	Sep 22, 2026	D100925
J2610358	Certificate of Analysis	Sep 22, 2026	D100925
J2610260	Certificate of Analysis	Sep 22, 2026	D100925
J2610259	Certificate of Analysis	Sep 22, 2026	D100925
I2602088	Certificate of Analysis	Sep 10, 2026	D100925
G2629343	Certificate of Analysis	Sep 09, 2026	D100925
G2629342	Certificate of Analysis	Sep 09, 2026	D100925
G2629333	Certificate of Analysis	Sep 09, 2026	D100925
G2629332	Certificate of Analysis	Sep 09, 2026	D100925
L2517310	Certificate of Analysis	Sep 09, 2026	D100925
D2507431	Certificate of Analysis	Sep 09, 2026	D100925
D2507430	Certificate of Analysis	Sep 09, 2026	D100925
G2322280	Certificate of Analysis	Sep 09, 2026	D100925
L2517306	Certificate of Analysis	Jul 09, 2026	D100925
L2517307	Certificate of Analysis	Mar 24, 2026	D100925
L2517305	Certificate of Analysis	Dec 06, 2025	D100925
D2507427	Certificate of Analysis	Mar 26, 2025	D100925
D2507478	Certificate of Analysis	Mar 26, 2025	D100925
D2507429	Certificate of Analysis	Mar 26, 2025	D100925
D2507428	Certificate of Analysis	Mar 26, 2025	D100925
H2415059	Certificate of Analysis	Mar 10, 2025	D100925
L2419044	Certificate of Analysis	Feb 17, 2025	D100925
G2322275	Certificate of Analysis	Nov 05, 2024	D100925
G2322277	Certificate of Analysis	Nov 05, 2024	D100925
C2408002	Certificate of Analysis	May 17, 2024	D100925
G2322269	Certificate of Analysis	Jan 17, 2024	D100925
C2330385	Certificate of Analysis	Apr 10, 2023	D100925
D2313853	Certificate of Analysis	Apr 10, 2023	D100925
D2313859	Certificate of Analysis	Apr 10, 2023	D100925
J2226356	Certificate of Analysis	Apr 10, 2023	D100925
J2226353	Certificate of Analysis	Apr 10, 2023	D100925
J2226355	Certificate of Analysis	Mar 07, 2023	D100925
J2226354	Certificate of Analysis	Nov 15, 2022	D100925

Solubilità	Solvent:DMSO, Max Conc. mg/mL: 32.85, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 32.85, Max Conc. mM: 100
Sensibilità	Air & Light & Heat sensitive
Indice di rifrazione	1.5049
Punto di infiammabilità (°C)	62℃
Punto di fusione (°C)	-44.5--44.1°C
Peso molecolare	328.500 g/mol
XLogP3	6.200
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	14
Exact Mass	328.24 Da
Monoisotopic Mass	328.24 Da
Topological Polar Surface Area	37.300 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	462.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	6
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	6
Covalently-Bonded Unit Count	1

Cervonic Acid（DHA） - Moligand™, ≥98% , Agonist of FFA1 receptor;Activator of K 2P10.1;Agonist of Retinoid X receptor-α;Activator of TRPA1, CAS No.6217-54-5, Agonist of FFA1 receptor;Activator of K 2P10.1;Agonist of Retinoid X receptor-α;Activator of TRPA1

Storage & shipping

Quality documents

Literature proof

Panoramica

Specifications

Documentazione

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

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