Chromotrope 2R - AR , CAS No.4197-07-3

CAS: 4197-07-3 Cat. No.: C100452 Molecular Weight: 468.37 Beilstein Registry Number: 16301 EC Number: 224-085-0

GRADE & PURITY AR

Synonyms

FT-0623802 | AKOS024285050 | UNII-LLE7AS9RKD | Q18620079 | AKOS015903361 | Chromotrope 2R | Disodium 4,5-dihydroxy-3-phenylazonaphthalene-2,7-disulphonate | 2-(Phenylazo)chromotropic acid disodium salt | sodium (E)-4,5-dihydroxy-3-(phenyldiazenyl)naphthal

Storage

Protected from light,Desiccated,Room temperature

Shipped In

Normal

Overview

Chromotrope 2R has been used in the Gomori trichrome staining in osteochondral tissues. It has also been used for the staining of eosinophils in lung sections.

Specifications

Synonyms

FT-0623802 | AKOS024285050 | UNII-LLE7AS9RKD | Q18620079 | AKOS015903361 | Chromotrope 2R | Disodium 4, 5-dihydroxy-3-phenylazonaphthalene-2, 7-disulphonate | 2-(Phenylazo)chromotropic acid disodium salt | sodium (E)-4, 5-dihydroxy-3-(phenyldiazenyl)naphthal

Specifications & Purity

AR

Biochemical and Physiological Mechanisms

Chromotrope 2R被用于体液和粪便样品中微孢子虫的染色。 它被用于改良型Gomori三色染色。 Chromotrope 2R对磷脂具有高亲和力，可用于组织学样品中线粒体和内质网膜的染色。

Storage

Protected from light, Desiccated, Room temperature

Shipped In

Normal

Grade

AR

Names and Identifiers

• Pubchem Sid: 488182595
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488182595
• Canonical Smiles: C1=CC=C(C=C1)N=NC2=C(C3=C(C=C(C=C3C=C2S(=O)(=O)[O-])S(=O)(=O)[O-])O)O.[Na+].[Na+]
• IUPAC Name: disodium;4,5-dihydroxy-3-phenyldiazenylnaphthalene-2,7-disulfonate
• InChIKey: GXEAXHYQKZAJGB-UHFFFAOYSA-L
• INCHI: 1S/C16H12N2O8S2.2Na/c19-12-8-11(27(21,22)23)6-9-7-13(28(24,25)26)15(16(20)14(9)12)18-17-10-4-2-1-3-5-10;;/h1-8,19-20H,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2
• Isomeric SMILES: C1=CC=C(C=C1)N=NC2=C(C3=C(C=C(C=C3C=C2S(=O)(=O)[O-])S(=O)(=O)[O-])O)O.[Na+].[Na+]
• WGK Germany: 3
• RTECS: QJ6418000
• Molecular Weight: 468.37
• Beilstein: 16301
• Reaxy-Rn: 7616654
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7616654&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Naphthalenes
      • Subclass Naphthalene sulfonic acids and derivatives
        • Level5 Naphthalene sulfonates
          • Level6 2-naphthalene sulfonates

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Naphthalenes
• Subclass: Naphthalene sulfonic acids and derivatives
• Intermediate Tree Nodes: Naphthalene sulfonates
• Direct Parent: 2-naphthalene sulfonates
• Alternative Parents: 2-naphthalene sulfonic acids and derivatives 1-sulfo,2-unsubstituted aromatic compounds Phenoxides Sulfonyls Organosulfonic acids Azo compounds Propargyl-type 1,3-dipolar organic compounds Organopnictogen compounds Organooxygen compounds Organic sodium salts Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homopolycyclic compounds
• Substituents: 2-naphthalene sulfonate - 2-naphthalene sulfonic acid or derivatives - Arylsulfonic acid or derivatives - 1-sulfo,2-unsubstituted aromatic compound - Phenoxide - Monocyclic benzene moiety - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Organosulfonic acid - Sulfonyl - Azo compound - Organic alkali metal salt - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Organic nitrogen compound - Organic salt - Organic sodium salt - Hydrocarbon derivative - Organic oxide - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic oxygen compound - Aromatic homopolycyclic compound
• Description: This compound belongs to the class of organic compounds known as 2-naphthalene sulfonates. These are organic aromatic compounds that contain a naphthalene moiety that carries a sulfonic acid group at the 2-position. Naphthalene is a bicyclic compound that is made up of two fused benzene ring.
• External Descriptors: organic sodium salt

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water (1 mg/ml).
• Sensitivity: Light sensitive.
• Molecular Weight: 468.400 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 2
• Exact Mass: 467.967 Da
• Monoisotopic Mass: 467.967 Da
• Topological Polar Surface Area: 196.000 Ų
• Heavy Atom Count: 30
• Formal Charge: 0
• Complexity: 756.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3

References

1. Zhenchao Lei, Ziyuan Huang, Yimin Lin, Yuwei Liu, Zhang Yan, Wenxiao Zheng, Huanxin Ma, Zhi Dang, Chunhua Feng.  (2022)  Boosting the oxidative capacity of the Fe(0)/O2 system via an air-breathing cathode.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:35999726] [10.1016/j.jhazmat.2022.129552]

2. Yusen Meng, Yuqing Qiao, Haifeng Zhou, Jingye Li, Bowu Zhang.  (2022)  A promising scalable route to construct GO-based laminate membranes for antifouling ultrafiltration.  Materials Advances,  3  (10): (4369-4380).  [PMID:] [10.1039/D1MA01111A]

3. Youchi Chen, Shuzhou Xing, Jie Jiang, Ruopeng Li, Yaqiang Li, Xin Li, Mingjie Li, Maozhong An, Jinqiu Zhang, Jiang Qin, Peixia Yang.  (2025)  Deciphering the Role of Chromotrope 2R in Conformal Copper Electrodeposition and Microstructural Control for PCB Through-Hole Metallization.  ELECTROCHIMICA ACTA,      [PMID:] [10.1016/j.electacta.2025.148106]