cis-Glimepiride - Moligand™, ≥98% , CAS No.684286-46-2

CAS: 684286-46-2 Cat. No.: C342547 Formula: C₂₄H₃₄N₄O₅S Peso molecolare: 490.62 Numero EC: 642-221-0

GRADE & PURITY Moligand™, ≥98%

Synonyms

CCRIS 7083 | GLIMEPIRIDE [USP-RS] | HMS2097C03 | HMS3677K06 | 24T6XIR2MZ | BPBio1_000751 | Glimepiride (JP17/USP/INN) | Glista OD | HOE 490 | SMR000466368 | GLIMEPIRIDE [USP MONOGRAPH] | Glimepiride Impurity A | HMS3714C03 | Glimepiride- Bio-X | Glymepiri

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Panoramica

cis-Glimepiride is the cis-isomer of Glimepiride found in a bulk drug substance.

Specifications

Sinonimi

CCRIS 7083 | GLIMEPIRIDE [USP-RS] | HMS2097C03 | HMS3677K06 | 24T6XIR2MZ | BPBio1_000751 | Glimepiride (JP17/USP/INN) | Glista OD | HOE 490 | SMR000466368 | GLIMEPIRIDE [USP MONOGRAPH] | Glimepiride Impurity A | HMS3714C03 | Glimepiride- Bio-X | Glymepiri

Specifiche e purezza

Moligand™, ≥98%

Condizioni di conservazione di stoccaggio

Store at -20°C,Desiccated

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Purezza

≥98%

Nomi e identificatori

• Sorrisi canonici: CCC1=C(CN(C1=O)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCC(CC3)C)C
• IUPAC Name: 4-ethyl-3-methyl-N-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide
• InChIKey: WIGIZIANZCJQQY-UHFFFAOYSA-N
• INCHI: 1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)
• Isomeri SMILES: CCC1=C(CN(C1=O)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCC(CC3)C)C
• Peso molecolare: 490.62
• Reaxy-Rn: 5365754
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5365754&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Benzenesulfonamides

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Benzenesulfonamides
• Intermediate Tree Nodes: Not available
• Direct Parent: Benzenesulfonamides
• Alternative Parents: Benzenesulfonyl compounds Sulfonylureas N-acyl ureas Pyrrolines Organosulfonic acids and derivatives Aminosulfonyl compounds Isoureas Propargyl-type 1,3-dipolar organic compounds Carboxylic acids and derivatives Carboximidamides Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Benzenesulfonamide - Benzenesulfonyl group - N-acyl urea - Sulfonylurea - Ureide - Pyrroline - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl - Aminosulfonyl compound - Isourea - Carboximidic acid derivative - Carboxylic acid derivative - Azacycle - Organoheterocyclic compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic oxide - Hydrocarbon derivative - Carbonyl group - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Aromatic heteromonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as benzenesulfonamides. These are organic compounds containing a sulfonamide group that is S-linked to a benzene ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (umani)

CYP2C9 Tchem Cytochrome P450 2C9 (1 Activities)

Discover Target: CYP2C9

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Proprietà chimiche e fisiche

• Solubilità: Soluble in chloroform.
• Punto di fusione (°C): 197-201°C (lit.)
• Peso molecolare: 490.600 g/mol
• XLogP3: 3.900
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 7
• Exact Mass: 490.225 Da
• Monoisotopic Mass: 490.225 Da
• Topological Polar Surface Area: 133.000 Ų
• Heavy Atom Count: 34
• Formal Charge: 0
• Complexity: 895.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1