CK 666 - 10mM in DMSO , CAS No.442633-00-3

CAS: 442633-00-3 Cat. No.: C424000 Formula: C₁₈H₁₇FN₂O Peso molecolare: 296.34 Numero EC: 687-170-5

QUALITÀ & PUREZZA 10mM in DMSO

Synonyms

CK-0944666 | UXRKUKRXVWJFER-UHFFFAOYSA-N | 2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide | 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)-ethyl]-benzamide | SCHEMBL3382638 | CK 666 | Z1038843750 | STK766770 | HY-16926 | 2-Fluoro-N-(2-(2-methyl-1H-indol-3-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifiche

Sinonimi

CK-0944666 | UXRKUKRXVWJFER-UHFFFAOYSA-N | 2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide | 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)-ethyl]-benzamide | SCHEMBL3382638 | CK 666 | Z1038843750 | STK766770 | HY-16926 | 2-Fluoro-N-(2-(2-methyl-1H-indol-3-

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

Potent inhibitor of actin polymerization. Inhibits the Arp2/3 (IC 50 = 17 μM), SpArp2/3 (IC 50 = 5 μM) and HsArp2/3 complexes (IC 50 = 4 μM) by preventing a shift into an active conformation.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

INHIBITOR

Nomi e identificatori

Pubchem Sid

528763747

Sorrisi canonici

CC1=C(C2=CC=CC=C2N1)CCNC(=O)C3=CC=CC=C3F

IUPAC Name

2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide

InChIKey

UXRKUKRXVWJFER-UHFFFAOYSA-N

INCHI

1S/C18H17FN2O/c1-12-13(14-6-3-5-9-17(14)21-12)10-11-20-18(22)15-7-2-4-8-16(15)19/h2-9,21H,10-11H2,1H3,(H,20,22)

Isomeri SMILES

CC1=C(C2=CC=CC=C2N1)CCNC(=O)C3=CC=CC=C3F

Peso molecolare

296.34

Reaxy-Rn

19720234

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=19720234&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Indoles and derivatives
      • Subclass Indoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Indoles and derivatives
• Subclass: Indoles
• Intermediate Tree Nodes: Not available
• Direct Parent: 3-alkylindoles
• Alternative Parents: 2-halobenzoic acids and derivatives Benzamides Benzoyl derivatives Fluorobenzenes Substituted pyrroles Aryl fluorides Vinylogous halides Heteroaromatic compounds Secondary carboxylic acid amides Azacyclic compounds Hydrocarbon derivatives Organic oxides Organofluorides Organonitrogen compounds Organooxygen compounds Organopnictogen compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 3-alkylindole - Halobenzoic acid or derivatives - 2-halobenzoic acid or derivatives - Benzamide - Benzoic acid or derivatives - Benzoyl - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Monocyclic benzene moiety - Benzenoid - Substituted pyrrole - Heteroaromatic compound - Vinylogous halide - Pyrrole - Carboxamide group - Secondary carboxylic acid amide - Azacycle - Carboxylic acid derivative - Organonitrogen compound - Organofluoride - Organohalogen compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organooxygen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as 3-alkylindoles. These are compounds containing an indole moiety that carries an alkyl chain at the 3-position.
• External Descriptors: organofluorine compound - indoles - benzamides

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Proprietà chimiche e fisiche

• Peso molecolare: 296.300 g/mol
• XLogP3: 3.800
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 296.132 Da
• Monoisotopic Mass: 296.132 Da
• Topological Polar Surface Area: 44.900 Ų
• Heavy Atom Count: 22
• Formal Charge: 0
• Complexity: 389.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1