Coelenterazine 400 a - ≥95% , CAS No.70217-82-2

CAS: 70217-82-2 Cat. No.: C332017 Formula: C₂₆H₂₁N₃O Peso molecolare: 391.46

GRADE & PURITY ≥95%

Synonyms

Coelenterazine 400 a is known as a bisdeoxy derivative of coelenterazine. | BlueSyn C | 2,8-dibenzyl-6-phenylimidazo[1,2-a]pyrazin-3-ol | coelenterazine-400a | 2,8-dibenzyl-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-one | AKOS030213259 | C-7010 | DTXSID10628592

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Panoramica

product description：

Coelenterazine 400 a is a chromophore that produces the chemiluminescence displayed by the Aequorin protein in the presence of Ca|2+|. Aequorin is employed as a chemiluminescent probe for intracellular Ca|2+|, and derivatives of this protein generated with various Coelenterazine derivatives produced a range of Ca|2+|probes with varying spectral properties. Coelenterazine 400 a is a bisdeoxy derivative of coelenterazine. Coelenterazine 400 a displays an emission maximum of 395nm following conversion by Renilla luciferase (Rluc). Coelenterazine 400 a is commonly paired with class 1 and 3 GFP acceptors.

Applications：

Coelenterazine 400 a is a blue emitting Rluc substrate for bioluminescence resonance energy transfer 2 (BRET2) studies.

Specifications

Sinonimi

Coelenterazine 400 a is known as a bisdeoxy derivative of coelenterazine. | BlueSyn C | 2,8-dibenzyl-6-phenylimidazo[1,2-a]pyrazin-3-ol | coelenterazine-400a | 2,8-dibenzyl-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-one | AKOS030213259 | C-7010 | DTXSID10628592

Specifiche e purezza

≥95%

Condizioni di conservazione di stoccaggio

Protected from light,Store at -20°C,Argon charged

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Nota

Stock Solution1. Let the vial warm to room temperature before opening to prevent condensation from entering the product.2. Dissolve the product in ethanol at a concentration of 0.4 mg/ml. Mix gently.3. Avoid solvents such as DMSO as they may cause oxidati

Purezza

≥95%

Nomi e identificatori

Pubchem Sid

504773439

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504773439

Sorrisi canonici

C1=CC=C(C=C1)CC2=C(N3C=C(N=C(C3=N2)CC4=CC=CC=C4)C5=CC=CC=C5)O

IUPAC Name

2,8-dibenzyl-6-phenylimidazo[1,2-a]pyrazin-3-ol

InChIKey

XNNYOKUWNAAJQW-UHFFFAOYSA-N

INCHI

1S/C26H21N3O/c30-26-23(17-20-12-6-2-7-13-20)28-25-22(16-19-10-4-1-5-11-19)27-24(18-29(25)26)21-14-8-3-9-15-21/h1-15,18,30H,16-17H2

Isomeri SMILES

C1=CC=C(C=C1)CC2=C(N3C=C(N=C(C3=N2)CC4=CC=CC=C4)C5=CC=CC=C5)O

Peso molecolare

391.46

Reaxy-Rn

36019358

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=36019358&ln=

Proprietà chimiche e fisiche

• Solubilità: Soluble in 0.1% warm acetone. Hardly soluble in water.
• Indice di rifrazione: n20D1.66 (Predicted)
• Punto di ebollizione (°C): 551.39° C at 760 mmHg (Predicted)
• Punto di fusione (°C): 94-98° C
• Peso molecolare: 391.500 g/mol
• XLogP3: 6.200
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 391.168 Da
• Monoisotopic Mass: 391.168 Da
• Topological Polar Surface Area: 50.400 Ų
• Heavy Atom Count: 30
• Formal Charge: 0
• Complexity: 524.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1