Compound 48/80 , Agonist of MRGPRX2, CAS No.94724-12-6, Agonist of MRGPRX2

CAS: 94724-12-6 Cat. No.: C275407 PubChem CID: 76522018

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Panoramica

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifications

Meccanismi biochimici e fisiologici

G protein activator; mast cell degranulator. Promotes histamine release, inhibits CaM (calmodulin), inhibits PLC (phospholipase C) and activates G proteins. Mechanism analogous to mastoparan . Active in vivo and in vitro .

Condizioni di conservazione di stoccaggio

Store at -20°C,Desiccated

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

AGONIST

Meccanismo d'azione

Agonist of MRGPRX2

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Nomi e identificatori

• Sorrisi canonici: [HH].[HH].[HH].CNCCC1=CC(=C(C=C1)OC)CC2=CC(=CC(=C2OC)CC3=C(C=CC(=C3)CCNC)OC)CCNC.Cl.Cl
• IUPAC Name: 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]phenyl]-N-methylethanamine;molecular hydrogen;dihydrochloride
• InChIKey: JBUOZOMGMXJHSP-UHFFFAOYSA-N
• INCHI: 1S/C32H45N3O3.2ClH.3H2/c1-33-14-11-23-7-9-30(36-4)26(17-23)21-28-19-25(13-16-35-3)20-29(32(28)38-6)22-27-18-24(12-15-34-2)8-10-31(27)37-5;;;;;/h7-10,17-20,33-35H,11-16,21-22H2,1-6H3;5*1H
• Isomeri SMILES: [HH].[HH].[HH].CNCCC1=CC(=C(C=C1)OC)CC2=CC(=CC(=C2OC)CC3=C(C=CC(=C3)CCNC)OC)CCNC.Cl.Cl
• CAS alternativo: 848035-21-2
• PubChem CID: 76522018

Obiettivi associati (umani)

MRGPRX2 Tchem Mas-related G-protein coupled receptor member X2 (1 Activities)

Discover Target: MRGPRX2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Proprietà chimiche e fisiche

• Solubilità: Soluble in water to 100 mM