Ω-conotoxin MVIIA, Voltage-gated N-type calcium channel alpha-1B subunit blocker, CAS No.1283221-32-8, Voltage-gated N-type calcium channel alpha-1B subunit blocker

CAS: 1283221-32-8 Cat. No.: rp174690 PubChem CID: 16135415
Disponibile su ordine
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
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Size
Germania (EU)
USA*
Price
Qty
500μg
rp174690-500μg
Su ordinazione · 8–12 settimane
2.082,49€
1mg
rp174690-1mg
Su ordinazione · 8–12 settimane
3.470,87€
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™ Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Product Name
Ω-conotoxin MVIIA, Voltage-gated N-type calcium channel alpha-1B subunit blocker, CAS No.1283221-32-8
Sinonimi
CYS-LYS-GLY-LYS-GLY-ALA-LYS-CYS-SER-ARG-LEU-MET-TYR-ASP-CYS-CYS-THR-GLY-SER-CYS-ARG-SER-GLY-LYS-CYS-NH2 | omega-Conopeptide MVIIA (Conus) | Ziconotide [USAN:INN] | HQPCSDADVLFHHO-LTKCOYKYSA-N | omega-Conotoxin mviia, conus magus | N-Desmethyl ofloxacin, a
Grado
Moligand™
Specifiche e purezza
Moligand™
Tipo di azione
BLOCKER, CHANNEL BLOCKER
Meccanismo d'azione
Voltage-gated N-type calcium channel alpha-1B subunit blocker
CAS
1283221-32-8
Tipo di molecola
Proteine
Stoccaggio e spedizione
Condizioni di conservazione di stoccaggio
Room temperature

Documentazione

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassePeptidomimetics
SubclassHybrid peptides
Intermediate Tree Nodes Not available
Direct ParentHybrid peptides
Alternative Parents 1-hydroxy-2-unsubstituted benzenoids  Benzene and substituted derivatives  Cyclic carboximidic acids  Secondary alcohols  Amino acids  Organic disulfides  Guanidines  Sulfenyl compounds  Propargyl-type 1,3-dipolar organic compounds  Polyols  Azacyclic compounds  Monocarboxylic acids and derivatives  Carboximidamides  Carboxylic acids  Dialkylthioethers  Hydrocarbon derivatives  Imines  Carbonyl compounds  Monoalkylamines  Organic oxides  Organopnictogen compounds  Primary alcohols  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Cyclic hybrid peptide - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Monocyclic benzene moiety - Benzenoid - Cyclic carboximidic acid - Amino acid or derivatives - Guanidine - Amino acid - Organic disulfide - Secondary alcohol - Carboximidic acid - Carboximidic acid derivative - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Azacycle - Polyol - Organoheterocyclic compound - Thioether - Carboximidamide - Sulfenyl compound - Dialkylthioether - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Hydrocarbon derivative - Organic oxygen compound - Organonitrogen compound - Organooxygen compound - Organosulfur compound - Carbonyl group - Alcohol - Primary alcohol - Primary amine - Amine - Organic nitrogen compound - Organopnictogen compound - Organic oxide - Imine - Primary aliphatic amine - Aromatic heteropolycyclic compound
DescrizioneThis compound belongs to the class of organic compounds known as hybrid peptides. These are compounds containing at least two different types of amino acids (alpha, beta, gamma, delta) linked to each other through a peptide bond.
External Descriptors Not available
Struttura 3D
Modello di struttura chimica interattiva





Obiettivi associati (umani)
CACNA1A Tchem Voltage-dependent P/Q-type calcium channel subunit alpha-1A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CACNA1B Tclin Voltage-dependent N-type calcium channel subunit alpha-1B (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CACNA1B Tclin Voltage-gated N-type calcium channel alpha-1B subunit (743 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Meccanismi d'azione
Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Informazioni genetiche
Alternate NamesCYS-LYS-GLY-LYS-GLY-ALA-LYS-CYS-SER-ARG-LEU-MET-TYR-ASP-CYS-CYS-THR-GLY-SER-CYS-ARG-SER-GLY-LYS-CYS-NH2 | omega-Conopeptide MVIIA (Conus) | Ziconotide [USAN:INN] | HQPCSDADVLFHHO-LTKCOYKYSA-N | omega-Conotoxin mviia, conus magus | N-Desmethyl ofloxacin, a
Reference
  • 1. Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration., The Journal of biological chemistry, Steegborn, C C and 7 more authors.
  • 2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., Proceedings of the National Academy of Sciences of the United States of America, Strausberg, Robert L RL and 83 more authors.
  • 3. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)., Human genetics, Wang, Jian J and Hegele, Robert A RA.
  • 4. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase., Biochemical and biophysical research communications, Lu, Y Y, O'Dowd, B F BF, Orrego, H H and Israel, Y Y.
  • 5. Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration., Clinical genetics, Wang, J J, Huff, A M AM, Spence, J D JD and Hegele, R A RA.
  • 6. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1., The Journal of biological chemistry, Yang, Guangdong G, Cao, Kun K, Wu, Lingyun L and Wang, Rui R.
  • 7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., Genome research, Gerhard, Daniela S DS and 115 more authors.
  • 8. Towards a proteome-scale map of the human protein-protein interaction network., Nature, Rual, Jean-François JF and 37 more authors.
  • 9. The DNA sequence and biological annotation of human chromosome 1., Nature, Gregory, S G SG and 178 more authors.
  • 10. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer., International journal of cancer, Moore, Lee E LE and 14 more authors. more
Calcolatori di soluzioni
Recensioni

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Domande frequenti

What is Moligand??
Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.
How should this product be stored?
Store at room temperature.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 1283221-32-8. InChIKey BPKIMPVREBSLAJ-QTBYCLKRSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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