Crotonic acid - Standard for GC, ≥99.9%(GC) , CAS No.107-93-7

CAS: 107-93-7 Cat. No.: C104150 Molecular Weight: 86.09 Beilstein Registry Number: 1719943 EC Number: 203-533-9
AVAILABLE TO ORDER
GRADE & PURITY Standard for GC ? GC reference standard — characterized compound for calibrating GC methods. Use to build calibration curves and verify GC quantitation. ≥99.9%(GC)
Synonyms
DTXSID30880973 | alpha-Crotonic acid | (E)-but-2-enoate | 2-Butenoic acid, (E)- | EINECS 223-077-4 | NCGC00259279-01 | Crotonic acid, liquid | NSC 206946 | UN2823 | DB02074 | (2E)-but-2-enoate | 2-butenoic acid, (2E)- | 2-Butenoicacid | alpha-Butenoic aci
Storage
Room temperature,Argon charged,Desiccated
Shipped In
FedEx DG Service
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Size
Status
Price
Qty
5g
C104150-5g
2
$27.90
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Why this grade

Standard for GC, ≥99.9%(GC) Standard for GC for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature,Argon charged,Desiccated Ships FedEx DG Service Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 14 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Crotonic acid undergoes esterification with butan-2-ol by following second order reaction kinetics.

Specifications

Synonyms
DTXSID30880973 | alpha-Crotonic acid | (E)-but-2-enoate | 2-Butenoic acid, (E)- | EINECS 223-077-4 | NCGC00259279-01 | Crotonic acid, liquid | NSC 206946 | UN2823 | DB02074 | (2E)-but-2-enoate | 2-butenoic acid, (2E)- | 2-Butenoicacid | alpha-Butenoic aci
Specifications & Purity
Standard for GC, ≥99.9%(GC)
Storage
Room temperature, Argon charged, Desiccated
Shipped In
FedEx DG Service
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Standard for GC
Purity
≥99.9%(GC)
Names and Identifiers
Canonical SmilesCC=CC(=O)O
IUPAC Name(E)-but-2-enoic acid
InChIKeyLDHQCZJRKDOVOX-NSCUHMNNSA-N
INCHI1S/C4H6O2/c1-2-3-4(5)6/h2-3H,1H3,(H,5,6)/b3-2+
Isomeric SMILES C/C=C/C(=O)O
WGK Germany 3
RTECS GQ2900000
UN Number 2823
Packing Group III
Molecular Weight 86.09
Beilstein 1719943
Reaxy-Rn 1098434
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1098434&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassLipids and lipid-like molecules
ClassFatty Acyls
SubclassFatty acids and conjugates
Intermediate Tree Nodes Not available
Direct ParentStraight chain fatty acids
Alternative Parents Unsaturated fatty acids  Monocarboxylic acids and derivatives  Carboxylic acids  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Unsaturated fatty acid - Straight chain fatty acid - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as straight chain fatty acids. These are fatty acids with a straight aliphatic chain.
External Descriptors Unsaturated fatty acids
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
SRR Tbio Serine racemase (249 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DAO Tchem D-amino-acid oxidase (802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hcar2 Hydroxycarboxylic acid receptor 2 (55 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus epidermidis (22802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterococcus hirae (484 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot NumberCertificate TypeDateItem
G2429332Certificate of AnalysisMay 19, 2026 C104150
E2529296Certificate of AnalysisMay 08, 2025 C104150
E2529297Certificate of AnalysisApr 11, 2025 C104150
G2429331Certificate of AnalysisJul 22, 2024 C104150
I2126145Certificate of AnalysisJul 11, 2023 C104150
K1920091Certificate of AnalysisJun 08, 2023 C104150
A2306622Certificate of AnalysisDec 06, 2022 C104150
Chemical and Physical Properties
SolubilitySoluble in water, soluble in ethanol, toluene, acetone, etc.
SensitivityAir sensitive
Refractive Index1.4228
Flash Point(°F)190.4 °F
Flash Point(°C)88℃
Boil Point(°C)185°C
Melt Point(°C)71.6°C
Molecular Weight86.090 g/mol
XLogP30.700
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass86.0368 Da
Monoisotopic Mass86.0368 Da
Topological Polar Surface Area37.300 Ų
Heavy Atom Count6
Formal Charge0
Complexity73.600
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds1
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
1. Fangfei Qin, Boyuan Li, Hui Wang, Sihui Ma, Jiaofeng Li, Shanglin Liu, Linghao Kong, Huangtao Zheng, Rongfeng Zhu, Yu Han, Mingdong Yang, Kai Li, Xiong Ji, Peng R. Chen.  (2023)  Linking chromatin acylation mark-defined proteome and genome in living cells.  CELL,      [PMID:36868209] [10.1016/j.cell.2023.02.007]
2. Lijun Gao, Liuyang Li, Yunqiu Li, Congcong He, Liming Zhou, Xiongwei Qu, Shaoming Fang.  (2023)  Effects of Europium Complex on Thermal and Photoluminescence Properties of Polyurethane-Europium Materials.  Polymers,  15  (5): (1064).  [PMID:36904305] [10.3390/polym15051064]
3. Hang Zhang, Shimin Kang, Jietai Li, Zhilin Li, Jie Chang, Yongjun Xu, Gaoqing Max Lu, Chenghua Sun.  (2020)  Near zero-waste biofuel production from bioderived polyhydroxybutyrate.  FUEL,      [PMID:] [10.1016/j.fuel.2020.119405]
4. Yuan Wang, Cailv Zheng, Yilin Wang, Hanxiang Chen, Yun Xu.  (2018)  Thermodynamic validation of double bond comprised ionic liquids for CO2 capture.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2018.11.019]
5. Zheng Cao, Yonghong Hu, Yumei Kai, Jiaojiao Li, Wenbiao Zhi, Wenge Yang.  (2013)  Solubilities of crotonic acid in different organic solvents at several temperatures from (278.15 to 333.15) K.  FLUID PHASE EQUILIBRIA,      [PMID:] [10.1016/j.fluid.2013.06.038]
6. Baoming Tian, Xue Zhou, Yan Geng, Jiangning Hu, Bangwei Ye, Peilong Sun, Kai Yang.  (2024)  Characterization and in vitro digestion of alkali-extracted polysaccharides from Grifola frondosa and its impacts on human gut microbiota.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2024.104499]
7. Zhentao Yao, Ge Zhang, Xin Wang, Jinjun Li, Yuting Qi, Yuanrong Jiang, Jie Gu, Liying Zhu, Xianrong Xu, Xiaoqiong Li.  (2024)  Microbiota responses to different brans are conserved within individuals and associated with processing parameters.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2024.104197]
8. Hong Cheng-Bin, Hua Wangde, Liu Lieke, Liu Haichao.  (2025)  Sustainable synthesis of α-ketoglutaric and methanetriacetic acids from biomass feedstocks.  Nature Communications,  16  (1): (1-8).  [PMID:39893175] [10.1038/s41467-025-56536-z]
9. Weijie Yang, Runping Wang, Lingqi Wang, Zhijian Tan.  (2024)  Switchable deep eutectic solvents for the extraction of phlorizin and trilobatin from sweet tea (Lithocarpus litseifolius (Hance) Chun).  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2024.129898]
10. Qingyan Yin, Xingwei Jiang, Huifeng Liu, Peiyue Wang, Xiaodong Su, Jun Zhang, Xinjian Lei, Junhu Yao.  (2025)  Enhancing milk quality and modulating plasma lipid metabolism of lactating dairy goats: The impact of bile acid supplementation.  Animal Nutrition,      [PMID:40896488] [10.1016/j.aninu.2024.12.008]
11. Baoming Tian, Xue Zhou, Shuo Pan, Wei Liu.  (2025)  Extraction, Characterization, and Impact of Polysaccharides From Zhonghuang No. 1 Etiolated-Green Tea on Human Fecal Microbiota.  Food Bioengineering,  (2): (166-181).  [PMID:] [10.1002/fbe2.70016]
12. Yanqin Zhu, Le Wang, Jinwen Zhao, Jiazhong Zhang, Qinhong Yin.  (2025)  A molecular imprinted fluorescence sensor based on EDTA-Cu quantum dots for methamphetamine recognition.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:41061422] [10.1016/j.saa.2025.127001]
13. Pinjiao Huang, Jiangning Hu, Kai Yang, Baoming Tian.  (2025)  Digestion characteristics of Changyanning formula and its regulatory effect on fecal microbiota and metabolites during in vitro fermentation.  FITOTERAPIA,      [PMID:41135752] [10.1016/j.fitote.2025.106949]
14. Zhaozhao Gao, Xingjia Xiang, Meng Yan, Yongqi Liu, Yucheng Wu, Xin Song, Xiangui Lin, Frank E. Löffler, Jun Zeng.  (2025)  Cometabolic defluorination of two poly-fluoroalkyl substances by a new Sphingopyxis isolate.  WATER RESEARCH,      [PMID:41389424] [10.1016/j.watres.2025.125149]
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