Crotonoside - ≥95%(HPLC) , CAS No.1818-71-9

CAS: 1818-71-9 Cat. No.: C168062 Formula: C₁₀H₁₃N₅O₅ Peso molecolare: 283.24 PubChem CID: 65085

GRADE & PURITY ≥95%(HPLC)

Synonyms

9H-Purin-2-ol, 6-amino-9-beta-D-ribofuranosyl- | Adenosine, 1,2-dihydro-2-oxo- | C08432 | 2-Oxo-3-hydroadenosine | 6-amino-9-((2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-3H-purin-2(9H)-one;9-?-D-Ribofuranosylisoguanine | MFCD049719

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Crotonoside, or isoguanosine, is a naturally occurring active isomer of guanosine that is found in the seeds of Croton tiglium.

Specifications

Sinonimi

9H-Purin-2-ol, 6-amino-9-beta-D-ribofuranosyl- | Adenosine, 1,2-dihydro-2-oxo- | C08432 | 2-Oxo-3-hydroadenosine | 6-amino-9-((2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-3H-purin-2(9H)-one;9-?-D-Ribofuranosylisoguanine | MFCD049719

Specifiche e purezza

≥95%(HPLC)

Meccanismi biochimici e fisiologici

Crotonoside, or isoguanosine, is a naturally occurring active isomer of guanosine that is found in the seeds of Croton tiglium, which is used in Traditional Chinese Medicine. It has shown more activity than adenosine in reducing the blood pressure of rabb

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

INHIBITOR

Purezza

≥95%(HPLC)

Nomi e identificatori

Pubchem Sid

504753956

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504753956

Sorrisi canonici

C1=NC2=C(NC(=O)N=C2N1C3C(C(C(O3)CO)O)O)N

IUPAC Name

6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-2-one

InChIKey

MIKUYHXYGGJMLM-UUOKFMHZSA-N

INCHI

1S/C10H13N5O5/c11-7-4-8(14-10(19)13-7)15(2-12-4)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1

Isomeri SMILES

C1=NC2=C(NC(=O)N=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N

PubChem CID

65085

Peso molecolare

283.24

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Classe Purine nucleosides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Classe: Purine nucleosides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Purine nucleosides
• Alternative Parents: Glycosylamines 6-aminopurines Pentoses Aminopyrimidines and derivatives Hydroxypyrimidines Imidolactams N-substituted imidazoles Tetrahydrofurans Heteroaromatic compounds Secondary alcohols Azacyclic compounds Oxacyclic compounds Primary alcohols Hydrocarbon derivatives Primary amines Organopnictogen compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Purine nucleoside - N-glycosyl compound - Glycosyl compound - 6-aminopurine - Pentose monosaccharide - Purine - Imidazopyrimidine - Aminopyrimidine - Hydroxypyrimidine - N-substituted imidazole - Imidolactam - Pyrimidine - Monosaccharide - Imidazole - Tetrahydrofuran - Azole - Heteroaromatic compound - Secondary alcohol - Oxacycle - Azacycle - Organoheterocyclic compound - Primary amine - Amine - Alcohol - Organic nitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Primary alcohol - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as purine nucleosides. These are compounds comprising a purine base attached to a ribosyl or deoxyribosyl moiety.
• External Descriptors: purine nucleoside

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (umani)

ADORA1 Tclin Adenosine A1 receptor (17603 Activities)

Discover Target: ADORA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADAL Tbio Adenosine deaminase-like protein (61 Activities)

Discover Target: ADAL

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Obiettivi associati (non umani)

Mus musculus (284745 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

J774.A1 (2436 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Bacillus anthracis (2936 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Adora2b Adenosine A2 receptor (1828 Activities)

Discover Target: Adora2b

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Meccanismi d'azione

Proprietà chimiche e fisiche

• Peso molecolare: 283.240 g/mol
• XLogP3: -3.000
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 2
• Exact Mass: 283.092 Da
• Monoisotopic Mass: 283.092 Da
• Topological Polar Surface Area: 153.000 Ų
• Heavy Atom Count: 20
• Formal Charge: 0
• Complexity: 544.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1