Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 12 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Cuprizone is a copper chelating agent that forms a deep blue copper ketone complex with copper (II). The copper ketone reaction can be used in colorimetric tests for the presence of trace copper. Cuprizone can be used to induce some schizophrenia-like behavior in mice. Cuprizone acts on copper enzymes , including SOD1, cytochrome oxidase, and DβH, thereby causing oxidative stress and increasing DA levels in certain brain regions such as the medial prefrontal cortex (PFC).
| Isomeric SMILES | C1CCC(=NNC(=O)C(=O)NN=C2CCCCC2)CC1 |
|---|---|
| WGK Germany | 3 |
| RTECS | RO2520000 |
| Molecular Weight | 278.35 |
| Beilstein | 2388004 |
| Reaxy-Rn | 2388004 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2388004&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Melt Point(°C) | 213°C |
|---|
| 1. Ziyang He, Qiang Huang, Liucheng Mao, Hongye Huang, Meiying Liu, Junyu Chen, Fengjie Deng, Naigen Zhou, Xiaoyong Zhang, Yen Wei. (2020) Direct surface modification of nanodiamonds with ionic copolymers for fast adsorptive removal of copper ions with high efficiency. Colloid and Interface Science Communications, [PMID:] [10.1016/j.colcom.2020.100278] |
| 2. Yan Liu, Hongye Huang, Defu Gan, Linru Guo, Meiying Liu, Junyu Chen, Fengjie Deng, Naigen Zhou, Xiaoyong Zhang, Yen Wei. (2018) A facile strategy for preparation of magnetic graphene oxide composites and their potential for environmental adsorption. CERAMICS INTERNATIONAL, [PMID:] [10.1016/j.ceramint.2018.07.081] |
| 3. Zhanying Li, Lin Shao, Zehai Ruan, Wenbin Hu, Lingbin Lu, Yongjun Chen. (2018) Converting untreated waste office paper and chitosan into aerogel adsorbent for the removal of heavy metal ions. CARBOHYDRATE POLYMERS, [PMID:29773376] [10.1016/j.carbpol.2018.04.003] |
| 4. Qiang Huang, Jiao Zhao, Meiying Liu, Junyu Chen, Xiaoli Zhu, Ting Wu, Jianwen Tian, Yuanqing Wen, Xiaoyong Zhang, Yen Wei. (2017) Preparation of polyethylene polyamine@tannic acid encapsulated MgAl-layered double hydroxide for the efficient removal of copper (II) ions from aqueous solution. Journal of the Taiwan Institute of Chemical Engineers, [PMID:] [10.1016/j.jtice.2017.10.019] |
| 5. Qiang Huang, Meiying Liu, Jiao Zhao, Junyu Chen, Guangjian Zeng, Hongye Huang, Jianwen Tian, Yuanqing Wen, Xiaoyong Zhang, Yen Wei. (2017) Facile preparation of polyethylenimine-tannins coated SiO2 hybrid materials for Cu2+ removal. APPLIED SURFACE SCIENCE, [PMID:] [10.1016/j.apsusc.2017.08.233] |
| 6. Huang Qiang, Liu Meiying, Guo Ren, Mao Liucheng, Wan Qing, Zeng Guangjian, Huang Hongye, Deng Fengjie, Zhang Xiaoyong, Wei Yen. (2016) Facile synthesis and characterization of poly(levodopa)-modified silica nanocomposites via self-polymerization of levodopa and their adsorption behavior toward Cu2+. JOURNAL OF MATERIALS SCIENCE, 51 (21): (9625-9637). [PMID:] [10.1007/s10853-016-0178-z] |
| 7. Ang Li, Runjun Lin, Chong Lin, Bianyang He, Tingting Zheng, Lingbin Lu, Yang Cao. (2016) An environment-friendly and multi-functional absorbent from chitosan for organic pollutants and heavy metal ion. CARBOHYDRATE POLYMERS, [PMID:27185140] [10.1016/j.carbpol.2016.04.070] |
| 8. Xiaoliang Zhang, Xiaohong Chen, Xiaofang Shi, Xiaochun Li, Hua-Zhong Yu. (2024) Microscale quantitation of heavy metals by back-scattering interferometry in conjunction with photothermal effect using a single laser beam. TALANTA, [PMID:39721133] [10.1016/j.talanta.2024.127390] |
| 9. Meiting Li, Zhuoyin Liu, Dan Peng, Yadong Liu, Lili Cheng, Baizhu Chen, Jie Liu. (2025) Multifunctional porous organic polymer-based hybrid nanoparticles for sonodynamically enhanced cuproptosis and synergistic tumor therapy. Acta Biomaterialia, [PMID:39993518] [10.1016/j.actbio.2025.02.045] |
| 10. Fang Li, Nuotong Shen, Qingcheng Li, Chen Yang, Limin Zhang, Mingjin Wang. (2024) Multiplexed microfluidic chip based flow injection analysis system for simultaneous determination of Fe(III), Mn(II) and Cu(II). MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2024.112346] |
| 11. Yaojun Ju, Yichen Yan, Xinhui Wang, Shan Li, Jialei Wang, Zixiao Wang, Yuling Dong, Junping Wang. (2025) Acer truncatum Bunge seeds oil ameliorated cuprizone induced cognitive decline and brain white matter impairment by improving sphingomyelin metabolism and neuroinflammation via activation of TREM2 signaling pathway. Food & Function, [PMID:41284332] [10.1039/D5FO03220B] |
| 12. Fei Chen, Sisi Wu, Jian Kuang, Sijia Xiang, Shenghu Wang, Siming Yuan, Kaiming Cao, Lu Yu, Wenming Yang, Liqin Tang, Yangzhong Liu. (2026) Rosmarinic Acid Is an hCtr1 Inhibitor that Interferes with Copper Transport Activity. INORGANIC CHEMISTRY, [PMID:41494012] [10.1021/acs.inorgchem.5c04906] |
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