d-Bicucullina - Moligand™, ≥98% , Antagonist of GABA A receptor α1 subunit;Antagonist of GABA A receptor α2 subunit;Antagonist of GABA A receptor α3 subunit;Antagonist of GABA A receptor α4 subunit;Antagonist of GABA A receptor α5 subunit;Antagonist of GA, Antagonist of GABA A receptor α1 subunit;Antagonist of GABA A receptor α2 subunit;Antagonist of GABA A receptor α3 subunit;Antagonist of GABA A receptor α4 subunit;Antagonist of GABA A receptor α5 subunit;Antagonist of GABA A receptor α6 subunit;Channel b
d-Bicucullina - Moligand™, ≥98% , Antagonist of GABA A receptor α1 subunit;Antagonist of GABA A receptor α2 subunit;Antagonist of GABA A receptor α3 subunit;Antagonist of GABA A receptor α4 subunit;Antagonist of GABA A receptor α5 subunit;Antagonist of GA, Antagonist of GABA A receptor α1 subunit;Antagonist of GABA A receptor α2 subunit;Antagonist of GABA A receptor α3 subunit;Antagonist of GABA A receptor α4 subunit;Antagonist of GABA A receptor α5 subunit;Antagonist of GABA A receptor α6 subunit;Channel b
GRADE & PURITYMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.≥98%
Conservare a 2-8°C, al riparo dalla luce, con carica di argon
Spedito in
Ghiaccio umido
Grado
Moligand™
Tipo di azione
ANTAGONIST, CHANNEL BLOCKER
Meccanismo d'azione
Antagonist of GABA A receptor α1 subunit;Antagonist of GABA A receptor α2 subunit;Antagonist of GABA A receptor α3 subunit;Antagonist of GABA A receptor α4 subunit;Antagonist of GABA A receptor α5 subunit;Antagonist of GABA A receptor α6 subunit;Channel b
Nota
Per quanto possibile, si consiglia di preparare e utilizzare le soluzioni lo stesso giorno. Tuttavia, se è necessario preparare in anticipo le soluzioni di riserva, si consiglia di conservarle in aliquote in fiale ben chiuse a -20°C. In genere, queste possono essere utilizzate per un mese. In genere, queste soluzioni sono utilizzabili fino a un mese. Prima dell'uso e dell'apertura della fiala, si consiglia di lasciare che il prodotto si equilibri a temperatura ambiente per almeno 1 ora. Per ulteriori informazioni sulla tossicità, consultare la SDS. Avete bisogno di ulteriori consigli su solubilità, uso e manipolazione? Per ulteriori informazioni, visitare la pagina delle domande frequenti (FAQ).
This compound belongs to the class of organic compounds known as phthalide isoquinolines. These are organic compounds with a structure characterized by an isoquinoline moiety linked to phthalide.
External Descriptors
Isoquinoline alkaloids
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
1.Xu Yi, Zhang Shuai, Sun Qiang, Wang Xu-Qiao, Chai Ya-Ni, Mishra Chandan, Chandra Shah Ram, Ai Jing. (2020) Cholinergic Dysfunction Involvement in Chronic Cerebral Hypoperfusion-Induced Impairment of Medial Septum–dCA1 Neurocircuit in Rats. Frontiers in Cellular Neuroscience, [PMID:33132852][10.3389/fncel.2020.586591]
3.Yan Zhang, Zihao Cheng, Jie Dai, Chunlei Zhang, Xueqian Cheng, Ying Peng, Weiwei Li, Jiang Zheng. (2026) Mechanism-based inactivation of CYP2C19 by bicuculline and related alteration in pharmacokinetics of clopidogrel. DRUG METABOLISM AND DISPOSITION, [PMID:41689871][10.1016/j.dmd.2026.100238]
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Recensioni
Recensioni dei clienti
Domande frequenti
What is the purity of this product?
This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How is this product shipped?
This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.
What is Moligand??
Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.
How should this product be stored?
Store at 2–8 °C, protected from light, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 485-49-4, the molecular formula is C20H17NO6, and the molecular weight is 367.35 g/mol. InChIKey IYGYMKDQCDOMRE-ZWKOTPCHSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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