D-Gluconic acid solution - 49-53 wt. % in H2O , CAS No.526-95-4

CAS: 526-95-4 Cat. No.: G111173 Molecular Weight: 196.16 Beilstein Registry Number: 1726055 EC Number: 208-401-4
AVAILABLE TO ORDER
GRADE & PURITY 49-53 wt. % in H2O
Synonyms
GCO | GLUCONIC ACID [INCI] | D-gluconic acid | GLUCONIC ACID (MART.) | sodium-gluconate | E574 | E-574 | Pesticide Code: 000104 | DB13180 | D-Glukonsaeure | Pentahydroxycaproate | CHEBI:33198 | GLUCONIC ACID [VANDF] | NCGC00260293-01 | 2,3,4,5,6-pentahydr
Storage
Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
25ml
G111173-25ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$9.90
100ml
G111173-100ml
5
$15.90
500ml
G111173-500ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$22.90
Enter a quantity for the sizes you want to add.
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Why this grade

49-53 wt. % in H2O for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 11 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

A chemical used in glycolytic pathway studies.

Specifications

Synonyms
GCO | GLUCONIC ACID [INCI] | D-gluconic acid | GLUCONIC ACID (MART.) | sodium-gluconate | E574 | E-574 | Pesticide Code: 000104 | DB13180 | D-Glukonsaeure | Pentahydroxycaproate | CHEBI:33198 | GLUCONIC ACID [VANDF] | NCGC00260293-01 | 2, 3, 4, 5, 6-pentahydr
Specifications & Purity
49-53 wt. % in H2O
Storage
Room temperature
Shipped In
Normal
Names and Identifiers
Pubchem Sid504751986
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504751986
Canonical SmilesC(C(C(C(C(C(=O)O)O)O)O)O)O
IUPAC Name(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid
InChIKeyRGHNJXZEOKUKBD-SQOUGZDYSA-N
INCHI1S/C6H12O7/c7-1-2(8)3(9)4(10)5(11)6(12)13/h2-5,7-11H,1H2,(H,12,13)/t2-,3-,4+,5-/m1/s1
Isomeric SMILES C([C@H]([C@H]([C@@H]([C@H](C(=O)O)O)O)O)O)O
RTECS LZ5057100
UN Number 3265
Molecular Weight 196.16
Beilstein 1726055
Reaxy-Rn 1910648
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1910648&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic oxygen compounds
ClassOrganooxygen compounds
SubclassCarbohydrates and carbohydrate conjugates
Intermediate Tree Nodes Not available
Direct ParentSugar acids and derivatives
Alternative Parents Medium-chain hydroxy acids and derivatives  Medium-chain fatty acids  Hydroxy fatty acids  Beta hydroxy acids and derivatives  Monosaccharides  Alpha hydroxy acids and derivatives  Secondary alcohols  Polyols  Monocarboxylic acids and derivatives  Carboxylic acids  Primary alcohols  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Gluconic_acid - Medium-chain hydroxy acid - Medium-chain fatty acid - Beta-hydroxy acid - Hydroxy fatty acid - Alpha-hydroxy acid - Fatty acyl - Fatty acid - Hydroxy acid - Monosaccharide - Secondary alcohol - Carboxylic acid derivative - Carboxylic acid - Polyol - Monocarboxylic acid or derivatives - Alcohol - Carbonyl group - Primary alcohol - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as sugar acids and derivatives. These are compounds containing a saccharide unit which bears a carboxylic acid group.
External Descriptors Uronic acids
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
F2 Tclin Thrombin (11687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE3A Tclin Phosphodiesterase 3A (3309 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE4A Tclin Phosphodiesterase 4A (1943 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA3 Tchem Adenosine A3 receptor (15931 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

27 results found

Lot NumberCertificate TypeDateItem
E2608404Certificate of AnalysisApr 23, 2026 G111173
E2608405Certificate of AnalysisApr 23, 2026 G111173
E2608406Certificate of AnalysisApr 23, 2026 G111173
E2608441Certificate of AnalysisApr 23, 2026 G111173
E2608442Certificate of AnalysisApr 23, 2026 G111173
H2525369Certificate of AnalysisAug 27, 2025 G111173
H2525472Certificate of AnalysisAug 27, 2025 G111173
H2525473Certificate of AnalysisAug 27, 2025 G111173
H2525474Certificate of AnalysisAug 27, 2025 G111173
H2525475Certificate of AnalysisAug 27, 2025 G111173
D2602116Certificate of AnalysisAug 23, 2025 G111173
I2519381Certificate of AnalysisAug 23, 2025 G111173
I2519380Certificate of AnalysisAug 23, 2025 G111173
I2519379Certificate of AnalysisAug 23, 2025 G111173
I2519378Certificate of AnalysisAug 23, 2025 G111173
I2519377Certificate of AnalysisAug 23, 2025 G111173
I2425218Certificate of AnalysisNov 24, 2022 G111173
G2311065Certificate of AnalysisNov 24, 2022 G111173
E2508058Certificate of AnalysisNov 24, 2022 G111173
B2401015Certificate of AnalysisNov 24, 2022 G111173
J2409026Certificate of AnalysisNov 24, 2022 G111173
K2401146Certificate of AnalysisNov 24, 2022 G111173
L2208112Certificate of AnalysisNov 24, 2022 G111173
L2208113Certificate of AnalysisNov 24, 2022 G111173
L2208116Certificate of AnalysisNov 24, 2022 G111173
L2208306Certificate of AnalysisNov 24, 2022 G111173
F2214260Certificate of AnalysisJun 15, 2022 G111173

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Chemical and Physical Properties
SolubilitySoluble in water.
Refractive Index1.4161
Boil Point(°C)102°C
Melt Point(°C)15°C
Molecular Weight196.160 g/mol
XLogP3-3.400
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass196.058 Da
Monoisotopic Mass196.058 Da
Topological Polar Surface Area138.000 Ų
Heavy Atom Count13
Formal Charge0
Complexity170.000
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
An Introduction to Research-Grade Carbohydrates: Decoding the “Glycan Language” and a Product-Selection Guide (with Tables 1–3)
Calcium Gluconate: Physicochemical Properties, Pharmacopoeial Quality Control, and Application Guidelines
How Organic Acids “Stabilize a System”: Selection Logic via the pH Window, Salt Forms, and Metal-Ion Management (with a navigation guide to Tables A–E)
The Role, Selection, and Validation of Chelating Agents in Daily Chemical Formulations
How Can Sodium Tripolyphosphate (STPP) Be Replaced? From Detergency Mechanisms to Formulation Choices for Low-Phosphorus/Phosphorus-Free Builder Systems
More Than a pH Adjuster: Mechanisms, Selection Logic, and Alternative Acid Source Analysis of Citric Acid in Home-Care Cleaning
Performance Sources and Formulation Applications of Enzyme-Based Ingredients in Daily Chemical Products: Fermentation Transformation, Enzymatic Reactions, and Application Principles
Citations of This Product
References
1. Shuqi Wang, Yingshuang Hui, Yulu Zhan, Lou Gao, Yahong Zhang, Yi Tang.  (2023)  Sugars as Emerging Hydrogen Donors in the Synthesis of Alditol via Catalytic Transfer Hydrogenation.  ChemCatChem,  15  (18): (e202300213).  [PMID:] [10.1002/cctc.202300213]
2. Rongxiu Qin, Haiyan Chen, Rusi Wen, Guiqing Li, Zhonglei Meng.  (2023)  Effect of Boric Acid on the Ionization Equilibrium of α-Hydroxy Carboxylic Acids and the Study of Its Applications.  MOLECULES,  28  (12): (4723).  [PMID:37375278] [10.3390/molecules28124723]
3. Pengmei Guo, Yu Liu, Xiaojia Xu, Guijin Ma, Xiaomin Hou, Yanying Fan, Mingsheng Zhang.  (2021)  Coronary hypercontractility to acidosis owes to the greater activity of TMEM16A/ANO1 in the arterial smooth muscle cells.  BIOMEDICINE & PHARMACOTHERAPY,      [PMID:34243598] [10.1016/j.biopha.2021.111615]
4. Zehua Zhang, Shuhua Li, Dandan Sun, Ying Yang, Zhanhai Wei, Changlu Wang, Laifeng Lu.  (2020)  Cultivation of Rhodosporidium paludigenum in gluconic acid enhances effectiveness against Penicillium digitatum in citrus fruit.  POSTHARVEST BIOLOGY AND TECHNOLOGY,      [PMID:] [10.1016/j.postharvbio.2020.111374]
5. Xuan Zhang, Jiawei Lin, Fang Pi, Tao Zhang, Chao Ai, Shujuan Yu.  (2020)  Rheological characterization of RG-I chicory root pectin extracted by hot alkali and chelators.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:32650011] [10.1016/j.ijbiomac.2020.07.020]
6. Yang He, Liankui Wen, Hansong Yu, Fei Zheng, Zhitong Wang, Xuanwei Xu, Hao Zhang, Yong Cao, Bixiang Wang, Baiji Chu, Jianyu Hao.  (2018)  Effects of high hydrostatic pressure-assisted organic acids on the copigmentation of Vitis amurensis Rupr anthocyanins.  FOOD CHEMISTRY,      [PMID:30064742] [10.1016/j.foodchem.2018.06.052]
7. Hui Chen, Zhongyin Chen, Ying Kuang, Shuang Li, Min Zhang, Jia Liu, Zhengguang Sun, Bingbing Jiang, Xueqin Chen, Cao Li.  (2018)  Stepwise-acid-active organic/inorganic hybrid drug delivery system for cancer therapy.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:29704741] [10.1016/j.colsurfb.2018.04.038]
8. Yujuan Chen, Qian Yang, Jing Chen, Guangyue Bai, Kelei Zhuo.  (2016)  Interaction of gluconate-based ionic liquids with common solvents: A study of volumetric, viscosity and conductivity properties.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2016.09.022]
9. Ao Xie, Jiaying Zhang, Hao-Zhe Xu, Xin-Gang Wang, Qiangliang Yu, Wenquan Lv, Meirong Cai, Feng Zhou.  (2024)  Enabling ultra-low wear and long-lived lubrication by DLC–supramolecular gel composite lubrication system under extreme contact stress.  TRIBOLOGY INTERNATIONAL,      [PMID:] [10.1016/j.triboint.2024.109364]
10. Pan Ma, Meili Ding, Wei Rong, Xi Liu, Jianfeng Yao.  (2022)  Acetic acid-assisted polyhydroxy acid modification of a zirconium-based MOF for synergistic CO2 fixation.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2022.108739]
11. Li Wang, Yi Zeng, Ruiqi yin, Yi Zheng, Zhen Li, Lihua Zhou, Guilong Yan, Zhenyu Li, Jingyu Chen, Jingjuan Lai, Dong Li, Dong Xiang, Chunxia Zhao, Hui Li, Bo Yu, Xuezhong Zhang, Han Li, Xungai Wang, Yuanpeng Wu.  (2025)  Phase-Selective Organogelators with pH-Triggered Recovery for Efficient Oil Spill Treatment.  LANGMUIR,      [PMID:40386986] [10.1021/acs.langmuir.5c01318]
Solution Calculators
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