D-Kynurenine - Moligand™, ≥98% , Agonist of HCA 3 receptor, CAS No.13441-51-5, Agonist of HCA 3 receptor

CAS: 13441-51-5 Cat. No.: S138168 Formula: C₁₀H₁₂N₂O₃ Peso molecolare: 208.21

QUALITÀ & PUREZZA Moligand™, ≥98%

Synonyms

KYNURENINE, (R)-|D-2-Amino-4-[2-aminophenyl]-4-oxobutanoic acid|D-Kynurenine, free base|K-8980|Kynurenine, D-|Benzenebutanoic acid, alpha,2-diamino-gamma-oxo-, (R)-|(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoicacid|D-Kynurenine free base (H-D-Asp(Ph(2-NH2))-OH)|(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid|BENZENEBUTANOIC ACID, .ALPHA.,2-DIAMINO-.GAMMA.-OXO-, (R)-|Benzenebutanoic acid, alpha,2-diamino-gamma-oxo-, (alphaR)-|(2R)-4-(2-aminophenyl)-2-azaniumyl-4-oxobutanoate|BENZENEBUTANOIC ACID, .ALPHA.,2-DIAMINO-.GAMMA.-OXO-, (.ALPHA.R)-|(2R)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid|KYNURENINE, (-)-|D-Kynurenine

Storage

Room temperature

Shipped In

Normal

Specifiche

Sinonimi

KYNURENINE, (R)- | D-2-Amino-4-[2-aminophenyl]-4-oxobutanoic acid | D-Kynurenine, free base | K-8980 | Kynurenine, D- | Benzenebutanoic acid, alpha,2-diamino-gamma-oxo-, (R)- | (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoicacid | D-Kynurenine free base (H-D-Asp(Ph(2-NH2))-OH) | (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid | BENZENEBUTANO Mostra altro

Specifiche e purezza

Moligand™, ≥98%

Meccanismi biochimici e fisiologici

D-Kynurenine may be used along with L-kynurenine to assess the specificity and kinetics of kynurenine metabolizing enzymes. D-Kynurenine is used to study the selectivity and activity of the G protein-coupled receptor, GPR109B. D-Kynurenine is used as a su

Condizioni di conservazione di stoccaggio

Room temperature

Spedito in

Normal

Grado

Moligand™

Tipo di azione

AGONIST

Meccanismo d'azione

Agonist of HCA 3 receptor

Purezza

≥98%

Nomi e identificatori

Pubchem Sid

488191727

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488191727

Sorrisi canonici

C1=CC=C(C(=C1)C(=O)CC(C(=O)O)N)N

IUPAC Name

(2R)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid

InChIKey

YGPSJZOEDVAXAB-MRVPVSSYSA-N

INCHI

1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)/t8-/m1/s1

Isomeri SMILES

C1=CC=C(C(=C1)C(=O)C[C@H](C(=O)O)N)N

Peso molecolare

208.21

Reaxy-Rn

2697333

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2697333&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Classe Organooxygen compounds
      • Subclass Carbonyl compounds
        • Level5 Ketones
          • Level6 Aryl ketones
            • Level7 Phenylketones
              • Level8 Alkyl-phenylketones

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Classe: Organooxygen compounds
• Subclass: Carbonyl compounds
• Intermediate Tree Nodes: Ketones - Aryl ketones - Phenylketones
• Direct Parent: Alkyl-phenylketones
• Alternative Parents: Butyrophenones D-alpha-amino acids Gamma-keto acids and derivatives Benzoyl derivatives Aryl alkyl ketones Aniline and substituted anilines Beta-amino ketones Vinylogous amides Amino acids Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Alkyl-phenylketone - Butyrophenone - Alpha-amino acid - Alpha-amino acid or derivatives - D-alpha-amino acid - Benzoyl - Gamma-keto acid - Aniline or substituted anilines - Aryl alkyl ketone - Monocyclic benzene moiety - Beta-aminoketone - Keto acid - Benzenoid - Vinylogous amide - Amino acid - Amino acid or derivatives - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Primary aliphatic amine - Amine - Hydrocarbon derivative - Organopnictogen compound - Organic oxide - Organic nitrogen compound - Organonitrogen compound - Primary amine - Aromatic homomonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as alkyl-phenylketones. These are aromatic compounds containing a ketone substituted by one alkyl group, and a phenyl group.
• External Descriptors: D-alpha-amino acid - kynurenine

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (umani)

HCAR3 Tchem Hydroxycarboxylic acid receptor 3 (1 Activities)

Discover Target: HCAR3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)

Discover Target: RGS4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Obiettivi associati (non umani)

GCN5 Histone acetyltransferase GCN5 (89 Activities)

Discover Target: GCN5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Meccanismi d'azione

Proprietà chimiche e fisiche

• Peso molecolare: 208.210 g/mol
• XLogP3: -2.200
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 208.085 Da
• Monoisotopic Mass: 208.085 Da
• Topological Polar Surface Area: 106.000 Ų
• Heavy Atom Count: 15
• Formal Charge: 0
• Complexity: 255.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Domande frequenti

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at room temperature.

How is this product shipped?

This product ships under standard ambient conditions. No temperature-controlled packaging is required.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 13441-51-5, the molecular formula is C10H12N2O3, and the molecular weight is 208.21 g/mol. InChIKey YGPSJZOEDVAXAB-MRVPVSSYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.