≥98% per flussi di lavoro cromatografici e analitici sensibili che richiedono un'interferenza minima della linea di base.
Store at -20°C Spedizione Ice chest + Ice pads. Consultare il COA specifico del lotto per le specifiche esatte.
SDS, COA, scheda tecnica e scheda delle specifiche disponibili per il download. COA specifico del lotto accessibile tramite ricerca per numero di lotto.
Citato in 0 pubblicazioni peer-reviewed su cromatografia, sintesi organica e reazioni di accoppiamento incrociato.
Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC 50 of 1.4 μM
In Vitro
Dapaconazole inhibits sterol 14α-demethylase cytochrome P450 activity with an IC 50 of 1.4 ± 0.3 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Dapaconazole (20 mg/kg; p.o.) shows that the bioavailability is 97.3 % . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male beagle dogs Dosage: 20 mg/kg (Pharmacokinetic Analysis) Administration: P.o. Result: Showed that the bioavailability was 97.3 %.
Form:Solid
IC50& Target:CYP26 1.4 μM (IC 50 )
Documento completo su pericoli, manipolazione, stoccaggio e conformità normativa.
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Visualizza scheda tecnica →Attributi di qualità completi e criteri di accettazione per questa qualità.
Visualizza scheda delle specifiche →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Classe | Benzene and substituted derivatives |
| Subclass | Trifluoromethylbenzenes |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Trifluoromethylbenzenes |
| Alternative Parents | Benzylethers Dichlorobenzenes N-substituted imidazoles Aryl chlorides Heteroaromatic compounds Dialkyl ethers Azacyclic compounds Organonitrogen compounds Organofluorides Organochlorides Hydrocarbon derivatives Alkyl fluorides |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Trifluoromethylbenzene - Benzylether - 1,3-dichlorobenzene - Chlorobenzene - Halobenzene - Aryl chloride - Aryl halide - N-substituted imidazole - Azole - Imidazole - Heteroaromatic compound - Azacycle - Organoheterocyclic compound - Dialkyl ether - Ether - Organonitrogen compound - Hydrocarbon derivative - Organohalogen compound - Organic oxygen compound - Organic nitrogen compound - Organochloride - Alkyl halide - Alkyl fluoride - Organooxygen compound - Organofluoride - Aromatic heteromonocyclic compound |
| Descrizione | This compound belongs to the class of organic compounds known as trifluoromethylbenzenes. These are organofluorine compounds that contain a benzene ring substituted with one or more trifluoromethyl groups. |
| External Descriptors | Not available |
| Solubilità | DMSO : 100 mg/mL (240.82 mM; Need ultrasonic) |
|---|---|
| Peso molecolare | 415.200 g/mol |
| XLogP3 | 5.600 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 6 |
| Exact Mass | 414.051 Da |
| Monoisotopic Mass | 414.051 Da |
| Topological Polar Surface Area | 27.100 Ų |
| Heavy Atom Count | 27 |
| Formal Charge | 0 |
| Complexity | 461.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
