dATP (100mM) - BioReagent, DNase, RNase free, PCR Reagent, Suitable for molecular biology, sterile, for DNA and RNA applications, ≥99%, 100mM , CAS No.1927-31-7

CAS: 1927-31-7 Cat. No.: D745241 Molecular Weight: 557.13(anhydrous) EC Number: 217-662-3

GRADE & PURITY Suitable for molecular biology, BioReagent, DNase, RNase free, PCR Reagent, Sterile, for DNA and RNA applications, ≥99%, 100mM

Synonyms

dATP | Deoxyadenosine triphosphate | 2'-deoxyadenosine 5'-triphosphate | 2'-deoxyadenosine triphosphate | deoxy-ATP | Deoxyadenosine 5'-triphosphate | 2'-Datp | 2'-deoxyadenosine-5'-triphosphate | 2'-Deoxyadenosine 5'-(tetrahydrogen triphosphate)

Storage

Store at -20°C,Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

Overview

dATP, 2'-deoxyadenosine 5'-triphosphate, is commonly used in PCR, real-time PCR, RT-PCR, cDNA or DNA synthesis, primer extension, DNA sequencing, and other conventional molecular biology applications. The molecular formula of dATP is C10H13N5O12P3Na3 with a molecular weight of 557.2 (491.2 in acid form). Its maximum absorption wavelength is 259nm.This dATP product is prepared with ultrapure water to a concentration of 100mM. The pH is titrated to 7.5 with high-purity NaOH solution.This product is free of DNase and RNase. This product can be directly used for various molecular biology applications such as PCR.
Precautions:
This product can be thawed at room temperature. Keep it on ice for use and store at -20ºC immediately after use.This product is for R&D only. Not for drug, household, or other uses.For your safety and health, please wear a lab coat and disposable gloves during the operation.
Instructions for Use:
None

Specifications

Synonyms

dATP | Deoxyadenosine triphosphate | 2'-deoxyadenosine 5'-triphosphate | 2'-deoxyadenosine triphosphate | deoxy-ATP | Deoxyadenosine 5'-triphosphate | 2'-Datp | 2'-deoxyadenosine-5'-triphosphate | 2'-Deoxyadenosine 5'-(tetrahydrogen triphosphate)

Specifications & Purity

BioReagent, DNase, RNase free, PCR Reagent, Suitable for molecular biology, sterile, for DNA and RNA applications, ≥99%, 100mM

Stability And Storage

Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Storage

Store at -20°C, Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

BioReagent, DNase, RNase free, for DNA and RNA applications, PCR Reagent, Sterile, Suitable for molecular biology

Purity

≥99%

Names and Identifiers

• PH: 7.0-7.5
• Canonical Smiles: C1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)N)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O.[Na+].[Na+].[Na+]
• IUPAC Name: [[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
• InChIKey: SUYVUBYJARFZHO-RRKCRQDMSA-N
• INCHI: 1S/C10H16N5O12P3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(25-7)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h3-7,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19)/t5-,6+,7+/m0/s1
• Isomeric SMILES: C1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)N)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O
• Alternate CAS: 54680-12-5
• Molecular Weight: 557.13(anhydrous)
• Reaxy-Rn: 24735345
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24735345&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Class Purine nucleotides
      • Subclass Purine deoxyribonucleotides
        • Level5 Purine deoxyribonucleoside triphosphates
          • Level6 Purine 2'-deoxyribonucleoside triphosphates

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Class: Purine nucleotides
• Subclass: Purine deoxyribonucleotides
• Intermediate Tree Nodes: Purine deoxyribonucleoside triphosphates
• Direct Parent: Purine 2'-deoxyribonucleoside triphosphates
• Alternative Parents: 6-aminopurines Monoalkyl phosphates Aminopyrimidines and derivatives N-substituted imidazoles Imidolactams Tetrahydrofurans Heteroaromatic compounds Secondary alcohols Oxacyclic compounds Azacyclic compounds Primary amines Organopnictogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Purine 2'-deoxyribonucleoside triphosphate - 6-aminopurine - Imidazopyrimidine - Purine - Aminopyrimidine - Monoalkyl phosphate - N-substituted imidazole - Organic phosphoric acid derivative - Phosphoric acid ester - Pyrimidine - Imidolactam - Alkyl phosphate - Azole - Imidazole - Heteroaromatic compound - Tetrahydrofuran - Secondary alcohol - Azacycle - Oxacycle - Organoheterocyclic compound - Organic oxygen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Amine - Organic nitrogen compound - Organic oxide - Organopnictogen compound - Alcohol - Hydrocarbon derivative - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as purine 2'-deoxyribonucleoside triphosphates. These are purine nucleotides with triphosphate group linked to the ribose moiety lacking a hydroxyl group at position 2.
• External Descriptors: Deoxyribonucleotides

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

References

1. Liangliang Wang, Xiufeng Wu, Guanyu Chen, Yawen Chen, Lilan Xu, Jianmin Wang, Jinghua Chen.  (2023)  Dual amplified electrochemical sensing coupling of ternary hybridization-based exosomal microRNA recognition and perchlorate-assisted electrocatalytic cycle.  BIOSENSORS & BIOELECTRONICS,      [PMID:] [10.1016/j.bios.2023.115783]

2. Liu Xufei, Qiu Shengqiang, Mei Peng, Zhang Qing, Yang Yingkui.  (2020)  Chain structure-dependent electrochemical performance of polyimide cathode materials for lithium-ion batteries.  JOURNAL OF MATERIALS SCIENCE,  56  (5): (3900-3910).  [PMID:] [10.1007/s10853-020-05510-9]

3. Liang-Liang Wang, Wen-Qian Chen, Yu-Ru Wang, Lu-Peng Zeng, Ting-Ting Chen, Guan-Yu Chen, Jing-Hua Chen.  (2020)  Numerous long single-stranded DNAs produced by dual amplification reactions for electrochemical detection of exosomal microRNAs.  BIOSENSORS & BIOELECTRONICS,      [PMID:32927348] [10.1016/j.bios.2020.112555]

4. Zheng Dan, Guo Peng, Xiong Juan, Wang Shengfu.  (2016)  Streptavidin Modified ZnO Film Bulk Acoustic Resonator for Detection of Tumor Marker Mucin 1.  Nanoscale Research Letters,  11  (1): (1-8).  [PMID:27624339] [10.1186/s11671-016-1612-5]

5. Wei Wen, Jing-Yi Huang, Ting Bao, Jun Zhou, Hong-Xing Xia, Xiu-Hua Zhang, Sheng-Fu Wang, Yuan-Di Zhao.  (2016)  Increased electrocatalyzed performance through hairpin oligonucleotide aptamer-functionalized gold nanorods labels and graphene-streptavidin nanomatrix: Highly selective and sensitive electrochemical biosensor of carcinoembryonic antigen.  BIOSENSORS & BIOELECTRONICS,      [PMID:27111123] [10.1016/j.bios.2016.04.039]

6. Chunyan Qin, Wei Wen, Xiuhua Zhang, Haoshuang Gu, Shengfu Wang.  (2015)  Visual detection of thrombin using a strip biosensor through aptamer-cleavage reaction with enzyme catalytic amplification.  ANALYST,  140  (22): (7710-7717).  [PMID:26451394] [10.1039/C5AN01712B]

7. Yunyu Zhao, Kaiyong Feng, Yingjian Yu.  (2024)  In situ preparation of zincophilic covalent–organic frameworks with low surface work function and high rigidity to stabilize zinc metal anodes.  Journal of Energy Chemistry,      [PMID:] [10.1016/j.jechem.2024.11.019]