DC 260126 - ≥98%(HPLC) , CAS No.346692-04-4

CAS: 346692-04-4 Cat. No.: D287987 Formula: C₁₆H₁₈FNO₂S Peso molecolare: 307.38 Numero EC: 809-022-2

GRADE & PURITY ≥98%(HPLC)

Synonyms

WNA69204 | C74786 | MFCD00784423 | N-(4-Butylphenyl)-4-fluorobenzene-1-sulfonamide | BDBM50196405 | N-(4-butylphenyl)-4-fluorobenzenesulfonamide | AKOS003265834 | SCHEMBL18058899 | BCP32685 | NCGC00387268-04 | HY-101906 | Oprea1_825888 | STK076838 | A8996

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Sinonimi

WNA69204 | C74786 | MFCD00784423 | N-(4-Butylphenyl)-4-fluorobenzene-1-sulfonamide | BDBM50196405 | N-(4-butylphenyl)-4-fluorobenzenesulfonamide | AKOS003265834 | SCHEMBL18058899 | BCP32685 | NCGC00387268-04 | HY-101906 | Oprea1_825888 | STK076838 | A8996

Specifiche e purezza

≥98%(HPLC)

Meccanismi biochimici e fisiologici

DC260126 is a FFA1 (GPR40) selective antagonist. In FFA1-expressing CHO cells, DC260126 blocks linoleic acid-induced Ca2+ elevation and ERK phosphorylation (IC50 = 6028 μM), as well as palmitic acid potentiated glucose-stimulated insulin secretion. The co

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

INHIBITOR

Purezza

≥98%(HPLC)

Nomi e identificatori

• Pubchem Sid: 504762235
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504762235
• Sorrisi canonici: CCCCC1=CC=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)F
• IUPAC Name: N-(4-butylphenyl)-4-fluorobenzenesulfonamide
• InChIKey: CNGHPXKWPGIDSK-UHFFFAOYSA-N
• INCHI: 1S/C16H18FNO2S/c1-2-3-4-13-5-9-15(10-6-13)18-21(19,20)16-11-7-14(17)8-12-16/h5-12,18H,2-4H2,1H3
• Isomeri SMILES: CCCCC1=CC=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)F
• Peso molecolare: 307.38
• Reaxy-Rn: 24554546
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24554546&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Sulfanilides

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Sulfanilides
• Intermediate Tree Nodes: Not available
• Direct Parent: Sulfanilides
• Alternative Parents: Benzenesulfonamides Benzenesulfonyl compounds Fluorobenzenes Organosulfonamides Aryl fluorides Aminosulfonyl compounds Organopnictogen compounds Organonitrogen compounds Organofluorides Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Benzenesulfonamide - Sulfanilide - Benzenesulfonyl group - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Organosulfonic acid amide - Aminosulfonyl compound - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl - Organosulfur compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Hydrocarbon derivative - Organic oxide - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Aromatic homomonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as sulfanilides. These are organic aromatic compounds containing a sulfanilide moiety, with the general structure RS(=O)(=O)NC1=CC=CC=C1.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (umani)

FFAR1 Tchem Free fatty acid receptor 1 (4763 Activities)

Discover Target: FFAR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FFAR4 Tchem G-protein coupled receptor 120 (2999 Activities)

Discover Target: FFAR4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Obiettivi associati (non umani)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: Solvent:DMSO, Max Conc. mg/mL: 30.74, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 30.74, Max Conc. mM: 100
• Peso molecolare: 307.400 g/mol
• XLogP3: 4.400
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 307.104 Da
• Monoisotopic Mass: 307.104 Da
• Topological Polar Surface Area: 54.600 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 391.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1