Demeclocycline - Moligand™, 10 mM in DMSO , CAS No.127-33-3

CAS: 127-33-3 Cat. No.: D1495347 Molecular Weight: 464.85
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1ml
D1495347-1ml
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$118.90
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Demeclocycline is an orally active tetracycline antibiotic . Demeclocycline impairs protein synthesis by binding to the 30S ribosomal subunit to inhibit binding of aminoacyl tRNA. Demeclocycline shows anti-bacterial activitise to a wide variety of bacterial infections .

Specifications

Specifications & Purity
Moligand™, 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Names and Identifiers
Isomeric SMILES CN(C)[C@H]1[C@@H]2C[C@@H]3[C@@H](C4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)Cl)O
Molecular Weight 464.85
Reaxy-Rn 25172468
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25172468&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Documents & Articles
Citations of This Product
References
1. Lingling Rong, Baoyin Zhang, Hongmu Qiu, Hailin Zhang, Jiayin Yu, Qing Yuan, Ligui Wu, Hong Chen, Yuanmin Mo, Xiaoming Zou, Xubiao Luo.  (2025)  Significant generational effects of tetracyclines upon the promoting plasmid-mediated conjugative transfer between typical wastewater bacteria and its mechanisms.  WATER RESEARCH,      [PMID:40749598] [10.1016/j.watres.2025.124290]
2. Lingling Rong, Ligui Wu, Tiao Zhang, Cui Hu, Haihui Tang, Hongcheng Pan, Xiaoming Zou.  (2023)  Significant Differences in the Effects of Nitrogen Doping on Pristine Biochar and Graphene-like Biochar for the Adsorption of Tetracycline.  MOLECULES,  29  (1): (173).  [PMID:38202756] [10.3390/molecules29010173]
3. Peng Wang, Huijie Xie, Fuqiao Guo, Baoluo He, Xianzong Wang, Shujuan Liu, Qian Ye, Weimin Liu.  (2023)  Thiadiazole Dimer-Functionalized Liquid Metal Nanoparticles for Anti-Corrosion and Friction Reduction.  ACS Applied Nano Materials,      [PMID:] [10.1021/acsanm.3c00217]
4. Xinyi Liao, Chen Chen, Zhijie Liang, Zhiwei Zhao, Fuyi Cui.  (2022)  Selective adsorption of antibiotics on manganese oxide-loaded biochar and mechanism based on quantitative structure–property relationship model.  BIORESOURCE TECHNOLOGY,      [PMID:36343776] [10.1016/j.biortech.2022.128262]
5. Jing Chen, Fanghong Xu, Qian Zhang, Shuying Li, Xiaoquan Lu.  (2021)  Tetracycline antibiotics and NH4+ detection by Zn–organic framework fluorescent probe.  ANALYST,  146  (22): (6883-6892).  [PMID:34632986] [10.1039/D1AN00894C]
6. Yang Yi, Yin Shuo, Wu Ling, Li Yongxin, Sun Chengjun.  (2021)  Determination of Six Tetracyclines in Eggs and Chicken by Dispersive Liquid-Liquid Microextraction Combined with High-Performance Liquid Chromatography.  JOURNAL OF AOAC INTERNATIONAL,  104  (6): (1549-1558).  [PMID:34190989] [10.1093/jaoacint/qsab082]
7. Jin Xu, Taiping Qing, Zixin Jiang, Peng Zhang, Bo Feng.  (2021)  Graphene oxide-regulated low-background aptasensor for the “turn on” detection of tetracycline.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:33993024] [10.1016/j.saa.2021.119898]
8. Zhou Li, Jia Zeng, Min Wang, Die Gao, Deng Li, Yingxi Zhu, Jiahao Lin, Zhiyu Chen, Famin Ke, Lixian Li, Dandan Wang.  (2025)  Enhanced specificity in molecular imprinting: A dual-role chitosan-bentonite substrate coupled with hierarchical monomers for ultrasensitive diclofenac potassium and metabolite enrichment.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41067339] [10.1016/j.ijbiomac.2025.148144]
Solution Calculators
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