Dexamethasone Solution (10mM) - BioReagent, for Cell culture, Sterile, 10 mM in DMSO , CAS No.50-02-2

CAS: 50-02-2 Cat. No.: C1524668 Formula: C₂₂H₂₉FO₅ Peso molecolare: 392.46 Beilstein Registry Number: 2066651 Numero EC: 200-003-9

QUALITÀ & PUREZZA BioReagent, for Cell culture, Sterile, 10 mM in DMSO

Synonyms

Dexamethasone Solution | DEX | DXM

Storage

Store at 2-8°C,Do not freeze

Shipped In

Wet ice

Panoramica

Dexamethasone is an adrenocortical hormone substance with multiple pharmacological effects including anti‑inflammatory, anti‑allergic, immunosuppressive and anti‑shock activities. It exerts certain physiological effects on cell culture, cell signal transduction and gene expression. Dexamethasone can induce disorder of hepatic glucose and lipid metabolism; inhibit the activation of the PI3K/Akt pathway and trigger osteoblast apoptosis; elevate intracellular ROS levels and mitochondrial superoxide production. It also induces the differentiation of human mesenchymal stem cells (MSCs), triggers autophagy in B‑cell acute lymphoblastic leukemia (B‑ALL), down‑regulates activated NF‑κB levels in immature dendritic cells (DCs), and suppresses their differentiation into mature DCs.

Dexamethasone Solution is a cell‑culture‑grade 10 mM stock solution. Researchers may dilute it at an appropriate ratio according to experimental requirements prior to direct use.

Product Properties:

CAS NO.: 50‑02‑2

Formula: C₂₂H₂₉FO₅

Molecular weight: 392.461

Appearance: Colorless transparent solution

Solubility: Soluble in ethanol and DMSO, slightly soluble in water

Melting point: 255～264 °C

Structure:

Precautions:

1. For your safety and health, please wear a lab coat and disposable gloves during operation.

2. This reagent is for research use only.

Specifiche

Sinonimi

Dexamethasone Solution | DEX | DXM

Specifiche e purezza

BioReagent, for Cell culture, Sterile, 10 mM in DMSO

Stabilità e conservazione

Store at 2-8°C long term (24 months). Store in the dark.

Condizioni di conservazione di stoccaggio

Store at 2-8°C,Do not freeze

Spedito in

Wet ice

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

BioReagent, per la coltura cellulare, Sterili

Product Line

Prodotti biologici

Proprietà del prodotto

ALogP

1.9

Nomi e identificatori

Isomeri SMILES

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C

WGK Germania

2

RTECS

TU3980000

CAS alternativo

23495-06-9,50-02-2

Numero NSC

34521

Termini MeSH

Decaject;Decaject L.A.;Decaject-L.A.;Decameth;Decaspray;Dexamethasone;Dexasone;Dexpak;Hexadecadrol;Hexadrol;Maxidex;Methylfluorprednisolone;Millicorten;Oradexon

Peso molecolare

392.46

Beilstein

2066651

Reaxy-Rn

2341697

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2341697&ln=

Proprietà chimiche e fisiche

• Solubilità: Soluble in ethanol and DMSO, slightly soluble in water
• Punto di fusione (°C): 262-264°C