DiAzKs - ≥95% , CAS No.1253643-88-7

CAS: 1253643-88-7 Cat. No.: A288380 Formula: C₁₁H₂₀N₄O₄ Peso molecolare: 272.3 Numero EC: 111-903-5

QUALITÀ & PUREZZA ≥95%

Synonyms

H-L-Photo-lysine | AbK | (2S)-2-amino-6-[2-(3-methyldiazirin-3-yl)ethoxycarbonylamino]hexanoic acid | (2S)-2-amino-6-({[2-(3-methyl-3H-diazirin-3-yl)ethoxy]carbonyl}amino)hexanoic acid

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Product Describtion:

DiAzKs (H-L-Photo-lysine) is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs acts as a UV light-activated photo-crosslinking probe.

Specifiche

Sinonimi

H-L-Photo-lysine | AbK | (2S)-2-amino-6-[2-(3-methyldiazirin-3-yl)ethoxycarbonylamino]hexanoic acid | (2S)-2-amino-6-({[2-(3-methyl-3H-diazirin-3-yl)ethoxy]carbonyl}amino)hexanoic acid

Specifiche e purezza

≥95%

Meccanismi biochimici e fisiologici

Unnatural amino acid. Acts as a UV light-activated photo-crosslinking probe when incorporated into proteins by pyrrolysyl tRNA synthetase/tRNACUApairs.

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥95%

Nomi e identificatori

Pubchem Sid

504771859

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504771859

Sorrisi canonici

CC1(N=N1)CCOC(=O)NCCCCC(C(=O)O)N

IUPAC Name

(2S)-2-amino-6-[2-(3-methyldiazirin-3-yl)ethoxycarbonylamino]hexanoic acid

InChIKey

LUCMNTLJAFTFDU-QMMMGPOBSA-N

INCHI

1S/C11H20N4O4/c1-11(14-15-11)5-7-19-10(18)13-6-3-2-4-8(12)9(16)17/h8H,2-7,12H2,1H3,(H,13,18)(H,16,17)/t8-/m0/s1

Isomeri SMILES

CC1(N=N1)CCOC(=O)NCCCC[C@@H](C(=O)O)N

Peso molecolare

272.3

Reaxy-Rn

54891734

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=54891734&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acids
              • Level8 L-alpha-amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
• Direct Parent: L-alpha-amino acids
• Alternative Parents: Medium-chain fatty acids Heterocyclic fatty acids Amino fatty acids Carbamate esters Amino acids Propargyl-type 1,3-dipolar organic compounds Monocarboxylic acids and derivatives Diazirines Carboxylic acids Azacyclic compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: L-alpha-amino acid - Medium-chain fatty acid - Amino fatty acid - Heterocyclic fatty acid - Fatty acid - Fatty acyl - Carbamic acid ester - Amino acid - Carboxylic acid - Diazirine - Monocarboxylic acid or derivatives - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Organoheterocyclic compound - Azacycle - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Primary amine - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Organic oxide - Hydrocarbon derivative - Amine - Aliphatic heteromonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Proprietà chimiche e fisiche

• Solubilità: Solvent:water, Max Conc. mg/mL: 2.72, Max Conc. mM: 10 with gentle warming; Solvent:1eq. HCl, Max Conc. mg/mL: 27.23, Max Conc. mM: 100
• Sensibilità: light ＆ heat ＆ moisture sensitive
• Peso molecolare: 272.300 g/mol
• XLogP3: -1.900
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 10
• Exact Mass: 272.148 Da
• Monoisotopic Mass: 272.148 Da
• Topological Polar Surface Area: 126.000 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 353.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1