Dicofol - analytical standard, ≥98% , CAS No.115-32-2

CAS: 115-32-2 Cat. No.: D110020 Molecular Weight: 370.49 Beilstein Registry Number: 1886299 EC Number: 204-082-0
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GRADE & PURITY Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. ≥98%
Synonyms
2,2,2-Trichloro-1,1-bis(4-cloro-fenil)-etanolo | 4-Chloro-alpha-(4-chlorophenyl)-alpha-(trichloromethyl)benzenemethanol | Ethanol, 2,2,2-Trichloro-1,1-bis(4-chlorophenyl)- | Milbol | Tricofol | DTMC | UNII-W4WMM0WS91 | FT-0624733 | p,p-Dicofol | AI3-23648
Storage
Store at 2-8°C
Shipped In
Wet ice
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Size
Status
Price
Qty
25mg
D110020-25mg
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$129.90
100mg
D110020-100mg
1
$399.90
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Why this grade

analytical standard, ≥98% Analytical standard for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 11 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Dicofol is a non-systemic insecticide used for a variety of crops. It can be synthesized from dichlorodiphenyltrichloroethane(DDT) via chlorination followed by hydrolysis.

Specifications

Synonyms
2, 2, 2-Trichloro-1, 1-bis(4-cloro-fenil)-etanolo | 4-Chloro-alpha-(4-chlorophenyl)-alpha-(trichloromethyl)benzenemethanol | Ethanol, 2, 2, 2-Trichloro-1, 1-bis(4-chlorophenyl)- | Milbol | Tricofol | DTMC | UNII-W4WMM0WS91 | FT-0624733 | p, p-Dicofol | AI3-23648
Specifications & Purity
analytical standard, ≥98%
Storage
Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Analytical standard
Purity
≥98%
Names and Identifiers
Canonical SmilesC1=CC(=CC=C1C(C2=CC=C(C=C2)Cl)(C(Cl)(Cl)Cl)O)Cl
IUPAC Name2,2,2-trichloro-1,1-bis(4-chlorophenyl)ethanol
InChIKeyUOAMTSKGCBMZTC-UHFFFAOYSA-N
INCHI1S/C14H9Cl5O/c15-11-5-1-9(2-6-11)13(20,14(17,18)19)10-3-7-12(16)8-4-10/h1-8,20H
Isomeric SMILES C1=CC(=CC=C1C(C2=CC=C(C=C2)Cl)(C(Cl)(Cl)Cl)O)Cl
WGK Germany 3
RTECS DC8400000
UN Number 3082
Packing Group III
Molecular Weight 370.49
Beilstein 1886299
Reaxy-Rn 1886299
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1886299&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassDiphenylmethanes
Intermediate Tree Nodes Not available
Direct ParentDiphenylmethanes
Alternative Parents Chlorobenzenes  Aryl chlorides  Tertiary alcohols  Chlorohydrins  Organochlorides  Hydrocarbon derivatives  Aromatic alcohols  Alkyl chlorides  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Diphenylmethane - Chlorobenzene - Halobenzene - Aryl chloride - Aryl halide - Tertiary alcohol - Halohydrin - Chlorohydrin - Organochloride - Organohalogen compound - Aromatic alcohol - Hydrocarbon derivative - Organic oxygen compound - Alkyl chloride - Alcohol - Alkyl halide - Organooxygen compound - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups.
External Descriptors Acaricides
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARA Tclin Peroxisome proliferator-activated receptor alpha (9197 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXRA Tclin Retinoid X receptor alpha (3637 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NFKB1 Tclin Nuclear factor NF-kappa-B p105 subunit (1459 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TP53 Tchem Cellular tumor antigen p53 (48468 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Homo sapiens (32628 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HIF1A Tchem Hypoxia-inducible factor 1 alpha (6027 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Tetranychus urticae (2600 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
I2413499Certificate of AnalysisJun 15, 2026 D110020
I2413500Certificate of AnalysisJun 15, 2026 D110020
K1925060Certificate of AnalysisJun 06, 2023 D110020
C2024163Certificate of AnalysisJan 24, 2022 D110020
Chemical and Physical Properties
SolubilitySlightly soluble in water, soluble in most organic solvents.
SensitivityLight sensitive.
Flash Point(°F)120.2℉
Flash Point(°C)49°C
Boil Point(°C)180°C
Melt Point(°C)78.5°C
Molecular Weight370.500 g/mol
XLogP34.300
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count2
Exact Mass369.907 Da
Monoisotopic Mass367.91 Da
Topological Polar Surface Area20.200 Ų
Heavy Atom Count20
Formal Charge0
Complexity292.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Li Wang, Yi Pan, Zhengwu Wang, Yuanfeng Wang, Xinlin Wei.  (2023)  Ultrasensitive Fluorescence Platform Based on AgNPs In Situ-Incorporated Zr-MOFs for the Detection of Organophosphorus Pesticides.  ACS Applied Materials & Interfaces,      [PMID:37676637] [10.1021/acsami.3c09354]
2. Yongfa Cheng, Lingzhi Cheong, Yongyong Li, Yongjiang Lou, Shiqian Fu.  (2023)  Sensitive and rapid electrochemical detection of nitroaromatic pesticides by the ordered macro-microporous ZIF-8 immobilized lipase-based sensor.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2023.109007]
3. Xiaohuan Zang, Qingyun Chang, Hongda Li, Xiaoxian Zhao, Shuaihua Zhang, Chun Wang, Zhi Wang.  (2022)  Construction of a ringent multi-shelled hollow MIL-88B as the solid-phase microextraction fiber coating for the extraction of organochlorine pesticides.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2022.122350]
4. Fengya Wang, Xiaobo Zhang, Changxin Huangfu, Mingzhen Zhu, Chunsheng Li, Liang Feng.  (2021)  The BODIPY-based chemosensor for the fluorometric determination of organochlorine pesticide dicofol.  FOOD CHEMISTRY,      [PMID:34509146] [10.1016/j.foodchem.2021.131033]
5. Na Li, Xi Yang, Fengping Chen, Guofang Zeng, Like Zhou, Xiaoke Li, Xun Tuo.  (2021)  Spectroscopic and in silico insight into the interaction between dicofol and human serum albumin.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:34455384] [10.1016/j.saa.2021.120277]
6. Jie Tang, Qiong Zhang, Jie Zhou, Huichao Fang, Haifeng Yang, Feng Wang.  (2021)  Investigation of pesticide residue removal effect of gelatinized starch using surface-enhanced Raman scattering mapping.  FOOD CHEMISTRY,      [PMID:34218109] [10.1016/j.foodchem.2021.130448]
7. Jinpei Huang, Yuhao Geng, Yundong Wang, Jianhong Xu.  (2019)  Efficient Production of Cyclopropylamine by a Continuous-Flow Microreaction System.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,      [PMID:] [10.1021/acs.iecr.9b02438]
8. Pang Yachao, Zang Xiaohuan, Wang Mengting, Chang Qingyun, Zhang Shuaihua, Wang Chun, Wang Zhi.  (2018)  Fibrous boron nitride nanocomposite for magnetic solid phase extraction of ten pesticides prior to the quantitation by gas chromatography.  MICROCHIMICA ACTA,  185  (12): (1-7).  [PMID:30488359] [10.1007/s00604-018-3103-0]
9. Shu Zhu, Shangying Qin, Chonghui Wei, Li Cen, Luyun Xiong, Xingyu Luo, Yilin Wang.  (2024)  Acetylcholine triggered enzymatic cascade reaction based on Fe7S8 nanoflakes catalysis for organophosphorus pesticides visual detection.  ANALYTICA CHIMICA ACTA,      [PMID:38553122] [10.1016/j.aca.2024.342464]
10. Wenfeng He, Si Dong, Fasheng Liu, Yunyun Du, Shanshan Zhu, Yulian Li, Yongliang Zheng, Ting Ding, Jinmei Shao, Weifang Gao, Qian Ouyang, Huiling Liu, Xiaoping Wang, Junquan Zeng.  (2025)  Dicofol induces developmental cardiotoxicity in zebrafish embryos through oxidative stress mechanisms.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,      [PMID:41046703] [10.1016/j.ecoenv.2025.119166]
11. Xiang Shen, Zheshan Duan, Xike Tian, Hongtao Zheng, Dongsheng Wang, Xubo Gao.  (2025)  The vertical distribution, sources and ecological risks of residual organochlorine pesticides in sediments of the North China's largest freshwater lake.  SCIENCE OF THE TOTAL ENVIRONMENT,      [PMID:41240894] [10.1016/j.scitotenv.2025.180881]
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